Downtown Hotels, Seneca

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
25 Oct - 26 Oct
Tomorrow
26 Oct - 27 Oct
Next weekend
31 Oct - 2 Nov
In two weeks
7 Nov - 9 Nov

Filter by

Guest rating
Guest rating
Star rating

1331 Cheap Hotels in Downtown - Specials, Reviews, & Last Minute Deals

Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123
2.5 star property
8.0 out of 10, Very good, (651)
"Friendly check in, clean room."
United States
connie
The price is AU$153
includes taxes & fees
5 Nov - 6 Nov
Quality Inn Seneca Clemson Area US-123
Aerial view
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 star property
9.0 out of 10, Wonderful, (1002)
"Very beautiful place to stay"
United States
Steven
The price is AU$208
includes taxes & fees
5 Nov - 6 Nov
Lakeside Lodge Clemson
Room, 1 King Bed, Non Smoking
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
6.8 out of 10, (708)
"The rooms have been renovated it was nice and clean especially for the price. "
United States
Sherri
The price is AU$122
includes taxes & fees
29 Oct - 30 Oct
Days Inn by Wyndham Seneca / Clemson Area
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
9.4 out of 10, Exceptional, (199)
"Nice hotel by the lake"
United States
Mike
The price is AU$203
includes taxes & fees
23 Nov - 24 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
Property amenity
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 star property
8.2 out of 10, Very good, (1003)
"Great value and great hotel. We would stay there again. "
United States
Matthew
The price is AU$143
includes taxes & fees
28 Oct - 29 Oct
Best Western Plus Clemson Hotel & Conference Center
Lobby
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 star property
9.2 out of 10, Wonderful, (777)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
United States
Gretchen
The price is AU$179
includes taxes & fees
5 Nov - 6 Nov
Tru by Hilton Seneca Clemson
Exterior
Woodspring Suites Anderson North I-85
Woodspring Suites Anderson North I-85
2.5 star property
7.6 out of 10, Good, (43)
"Great service and very helpful employees"
United States
Braden
The price is AU$126
includes taxes & fees
26 Oct - 27 Oct
Woodspring Suites Anderson North I-85
Lobby
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 star property
8.2 out of 10, Very good, (1006)
"I loved the quietness and the staff was great. "
United States
Chantel
The price is AU$172
includes taxes & fees
5 Nov - 6 Nov
Comfort Inn & Suites Clemson - University Area
Lobby lounge
Inn @ Clemson
Inn @ Clemson
2.5 star property
8.0 out of 10, Very good, (1010)
"Very nice staff and great place to stay"
United States
Kimberley
The price is AU$597
includes taxes & fees
1 Nov - 2 Nov
Inn @ Clemson
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
9.8 out of 10, Exceptional, (43)
"The place was absolutely magnificent."
United States
David
The price is AU$285
includes taxes & fees
5 Nov - 6 Nov
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Exterior
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
9.4 out of 10, Exceptional, (648)
"Great place to stay"
United States
Jose
The price is AU$233
includes taxes & fees
24 Nov - 25 Nov
Hampton Inn & Suites Seneca-Clemson Area
Superior Room, 2 Queen Beds
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (714)
"Very nice hotel, great staff"
United States
Erin
The price is AU$322
includes taxes & fees
27 Oct - 28 Oct
The Shepherd Hotel Downtown Clemson
View from property
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3.0 star property
9.6 out of 10, Exceptional, (945)
"Amazing place to stay. "
United States
Debra
The price is AU$254
includes taxes & fees
29 Oct - 30 Oct
Clemson University's James F. Martin Inn
Outdoor pool
Baymont by Wyndham Anderson Clemson
Baymont by Wyndham Anderson Clemson
2.5 star property
7.0 out of 10, Good, (824)
"Clean room | Staff | Parking | Family-friendly"
United States
Vladimir
The price is AU$101
includes taxes & fees
3 Nov - 4 Nov
Baymont by Wyndham Anderson Clemson
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
9.0 out of 10, Wonderful, (572)
"Good breakfast, clean "
United States
Carol
The price is AU$176
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Gazebo
Days Inn by Wyndham Clemson
Days Inn by Wyndham Clemson
3.5 star property
7.0 out of 10, Good, (193)
"Rooms were clean. Check in was easy. TV and AC both worked great. Conveniently located to dining and shopping options. No issues or complaints. Would stay again. "
United States
Sean
The price is AU$136
includes taxes & fees
29 Oct - 30 Oct
Days Inn by Wyndham Clemson
Exterior
Hilton Garden Inn Anderson
Hilton Garden Inn Anderson
3.0 star property
9.0 out of 10, Wonderful, (656)
"Ez check in"
United States
Samuel
The price is AU$187
includes taxes & fees
2 Nov - 3 Nov
Hilton Garden Inn Anderson
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
8.2 out of 10, Very good, (1000)
"Great stay"
United States
lee
The price is AU$133
includes taxes & fees
26 Oct - 27 Oct
Microtel Inn & Suites by Wyndham Anderson/Clemson
Fireplace
Courtyard Marriott Clemson
Courtyard Marriott Clemson
3.0 star property
9.0 out of 10, Wonderful, (518)
"Excellent!!! We loved everything about it!!! "
United States
Sarah
The price is AU$201
includes taxes & fees
9 Nov - 10 Nov
Courtyard Marriott Clemson
Lobby
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 star property
8.4 out of 10, Very good, (623)
"Convenient for Clemson visits."
United States
Kathleen
The price is AU$165
includes taxes & fees
5 Nov - 6 Nov
Best Western Seneca-Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Our guide on where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Keowee Reservoir and Oconee County Library Seneca Branch.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Keowee Reservoir and Oconee County Library Seneca Branch are some notable places to visit nearby.

Top Downtown Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"World-class Everything! Friendly well-trained staff, great food, super hangout on the roof. We’re coming back!"
Stephen 2-night trip
Posted 4 days ago
The Shepherd Hotel Downtown Clemson

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels will I be able to find in Downtown?
Expedia has 9 Downtown hotels and other accommodation options, and one might make a good home base for venturing out into the greater Seneca area.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Seneca Historic District, Oconee County Library Seneca Branch and Bertha Lee Strickland Cultural Museum are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, The Gauntlet and Seneca City Hall are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Wyndham Plaza or Cross Creek Plantation Golf.