Downtown Holidays
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Our guide on where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Our pick of the best Downtown Hotel Deals
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
The price is AU$133 per night from 3 Feb to 4 Feb
AU$133
3 Feb - 4 Feb
includes taxes & fees
7.8/10 Good! (672 reviews)
Our stay was very nice. Clean room. The outside was clean.
Reviewed on 20 Jan 2026
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
The price is AU$303 per night from 1 Feb to 2 Feb
AU$303
1 Feb - 2 Feb
includes taxes & fees
9.8/10 Exceptional! (752 reviews)
Would definitely stay here again. Was an amazing hotel.
Reviewed on 21 Jan 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is AU$153 per night from 3 Feb to 4 Feb
AU$153
3 Feb - 4 Feb
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
Rooms are clean. Staff was very pleasant.
Reviewed on 20 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.