Book Orangeburg County Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top Cities in Orangeburg County

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Orangeburg County hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,429 reviews)
"Room were very clean and staff was very helpful. I would stay there again."
United States
Charolette
The price is AU$125
includes taxes & fees
23 Feb - 24 Feb
Baymont by Wyndham Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (728 reviews)
"Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. "
United States
Susan
The price is AU$168
includes taxes & fees
25 Feb - 26 Feb
Tru By Hilton Santee

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,006 reviews)
"Great stay"
United States
Thomas
The price is AU$179
includes taxes & fees
8 Mar - 9 Mar
Tru by Hilton Orangeburg

Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,002 reviews)
"Clean rooms, good location, nice and polite staff"
United States
Kenya
The price is AU$150
includes taxes & fees
22 Feb - 23 Feb
Spark by Hilton Orangeburg

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,003 reviews)
"Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed."
United States
Marcia
The price is AU$218
includes taxes & fees
23 Feb - 24 Feb
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,001 reviews)
"Liked the size of the room, the staff and the breakfast."
United States
Virginia
The price is AU$187
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn Santee-I-95

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (726 reviews)
"Overall a great place to stay!"
United States
Troy
The price is AU$132
includes taxes & fees
4 Mar - 5 Mar
Fairfield Inn by Marriott Orangeburg

Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very good, (574 reviews)
"Nice room and great breakfast."
United States
Michelle
The price is AU$166
includes taxes & fees
25 Feb - 26 Feb
Comfort Inn & Suites Orangeburg

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,001 reviews)
"Everything was great!"
United States
Julie
The price is AU$181
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Santee by IHG

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (783 reviews)
"We travel regularly and this was the best breakfast of any of the places we had stayed. Facility was clean and service was friendly."
United States
Janet
The price is AU$204
includes taxes & fees
8 Mar - 9 Mar
Hampton Inn & Suites Orangeburg

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,001 reviews)
"Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!"
Canada
Roger
The price is AU$176
includes taxes & fees
22 Feb - 23 Feb
Best Western Plus Santee Inn

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,004 reviews)
"Clean rooms, nice staff, decent breakfast "
United States
Dale
The price is AU$166
includes taxes & fees
25 Feb - 26 Feb
Comfort Inn & Suites Santee

Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (806 reviews)
"Room was clean and comfortable. The employees were helpful and efficient. Overall good stay"
United States
margaret
The price is AU$165
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Express & Suites Orangeburg by IHG

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,000 reviews)
"The evening clerk is a joy, so friendly and helpful! Room clean and comfortable. Nice stay for passing through. "
United States
Debra
The price is AU$124
includes taxes & fees
23 Feb - 24 Feb
Travelodge by Wyndham Orangeburg

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (703 reviews)
"3rd stay at this location would highly recommend "
United States
Athanassios
The price is AU$165
includes taxes & fees
26 Feb - 27 Feb
SpringHill Suites by Marriott Orangeburg

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (476 reviews)
"Clean room but needs an exhaust fan in the bathroom "
United States
Leesa
The price is AU$93
includes taxes & fees
26 Feb - 27 Feb
Quality Inn & Suites Santee I-95

Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
6.0 out of 10, (1,000 reviews)
"The rooms were clean and staff was courteous. "
United States
Yojuana
The price is AU$87
includes taxes & fees
25 Feb - 26 Feb
Baymont by Wyndham Orangeburg North

Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg
2.0 star property
Orangeburg
6.8 out of 10, (916 reviews)
"Always a pleasure to stay, staff is very welcoming and the breakfast is a great plus!!"
United States
Debra
The price is AU$90
includes taxes & fees
1 Mar - 2 Mar
Super 8 by Wyndham, Orangeburg

Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (636 reviews)
"Clean and staff very pleasant"
United States
Larry
The price is AU$92
includes taxes & fees
25 Feb - 26 Feb
Quality Inn & Suites Orangeburg

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (699 reviews)
"Nice quiet room and a delicious breakfast at a reasonable rate."
United States
Joseph B
The price is AU$97
includes taxes & fees
22 Feb - 23 Feb
Travelodge by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

Great weekend hotel deals in Orangeburg County, SC

Showing deals for:27 Feb - 1 Mar

Save an average of 15% on thousands of hotels when you're signed in

Top Orangeburg County Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from AU$87 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at AU$87 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed holiday at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveller experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Sign up to One Key™ for free and unlock Member Prices, rewards for future trips and exclusive perks each and every time you book. Plenty of Orangeburg County hotels on Expedia also have flexible policies, so you can change or cancel without the stress. No matter your budget or plans, you're sure to find a stay that's just right with Expedia.