Commerce Travel Guide
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is AU$155 per night from 3 Dec to 4 Dec
AU$155
3 Dec - 4 Dec
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
The room was clean and comfy. The staf was friendly, courteous and efficient. Many thanks!
Reviewed on 5 Nov 2025

The Riverview
777 Main St, Cape Girardeau, MO
The price is AU$157 per night from 16 Nov to 17 Nov
AU$157
16 Nov - 17 Nov
includes taxes & fees
Stay at this 4-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (447 reviews)
I didn't realize there was free breakfast...? But, there is a great Starbucks just off the lobby and I rate that a 5! This is a really nice hotel, pretty much brand new, at this price point. We didn't use the casino, but it looked clean and nice, too. We will stay here anytime we're in Cape. ...
Reviewed on 9 Nov 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
The price is AU$135 per night from 16 Nov to 17 Nov
AU$135
16 Nov - 17 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jackson. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (649 reviews)
Very quiet and comfortable. The juice selection seemed a but spoiled and disappointing.
Reviewed on 13 Nov 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a garden, and in-room jetted tubs. Popular attractions eDen Spa & Salon and Riverfront Park are located ...
9.6/10 Exceptional! (42 reviews)
Great space, very unique. Comfortable beds, slept very well there
Reviewed on 24 Oct 2025

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
Stay at this cabin in Alexander County. Enjoy patios, an in-room coffeemaker, and air conditioning.
9.8/10 Exceptional! (34 reviews)
Beautiful place, host was kind and and quick to respond to messages
Reviewed on 7 Aug 2025

Quaint, Beautiful Home next to SEMO and Hospital
Cape Girardeau
Stay at this vacation home in Cape Girardeau. Enjoy laundry facilities, an in-room coffeemaker, and in-room fireplaces. Popular attractions Show Me Center and ...
9.8/10 Exceptional! (40 reviews)
Beautiful location
Reviewed on 19 Oct 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
