Commerce Holidays

Name: Drury Inn & Suites Sikeston, MO
Price range: AU$183
Rating: 9.4

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to AU$703 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Commerce Holiday

Commerce Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Cape Girardeau Municipal Airport (CGI)
Max Temp Winter	7ºC
Max Temp Summer	29ºC
Top Sights	Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site

Our pick of the best Commerce Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO

Fully refundableReserve now, pay when you stay

AU$168

8 Apr - 9 Apr

includes taxes & fees

9.6/10 Exceptional! (1,000 reviews)

Parking was available for my handicap son ,breakfast was great,very clean room and friendly staff

Reviewed on 31 Mar 2026

The Riverview

777 Main St Cape Girardeau MO

Fully refundableReserve now, pay when you stay

AU$186

8 Apr - 9 Apr

includes taxes & fees

9.4/10 Exceptional! (538 reviews)

Really nice rooms

Reviewed on 31 Mar 2026

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

Fully refundableReserve now, pay when you stay

AU$183

5 Apr - 6 Apr

includes taxes & fees

9.4/10 Exceptional! (1,000 reviews)

Our first visit to a Drury Inn — what an amazing place. Not only was there an excellent breakfast with many choices, but there was also a light dinner served. This was all included for a very reasonable price. Our room was very clean and comfortable. We will definitely be looking for more Drury Inns ...

Reviewed on 30 Mar 2026

See all 82 properties in Commerce

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.