Top Hotels Near Casa Santo Domingo Museum in Antigua Guatemala from AU$135

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Accommodation near Casa Santo Domingo Museum

Villa Las Mil Flores

4.0 star property
Historic Center, 0.6 km from Casa Santo Domingo Museum
10.0 out of 10, Exceptional, (83)
"the room is magical. the staff in flawlessly wonderful"
United States
VICTOR
The price is AU$518
includes taxes & fees
8 Dec - 9 Dec
Villa Las Mil Flores

Hotel Aurora

3.5 star property
Historic Center, 0.2 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (386)
"Quiet and beautiful. "
United States
Richard
The price is AU$157
includes taxes & fees
11 Dec - 12 Dec
Hotel Aurora

San Rafael Hotel

4.0 star property
Historic Center, 0.7 km from Casa Santo Domingo Museum
9.8 out of 10, Exceptional, (438)
"Helpful and courteous staff, clean room, excellent location and beautiful common areas. Super quiet and peaceful. "
United States
Ricardo
The price is AU$345
includes taxes & fees
21 Dec - 22 Dec
San Rafael Hotel

Barbaras Boutique Hostel

2.0 star property
0.7 km from Casa Santo Domingo Museum
10.0 out of 10, Exceptional, (23)
"Clean room, super friendly staff"
United States
Doylesa
The price is AU$208
includes taxes & fees
17 Dec - 18 Dec
Barbaras Boutique Hostel

Luna Maya Boutique Hotel

3.0 star property
0.4 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (20)
"Very helpful staff the breakfast was delicious and the room was super clean and comfortable."
Canada
Adam
The price is AU$135
includes taxes & fees
14 Dec - 15 Dec
Luna Maya Boutique Hotel

Casa Noble Hotel

3.0 star property
0.7 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (164)
"Staff very friendly, breakfeast was good"
United States
HUBER
The price is AU$225
includes taxes & fees
9 Dec - 10 Dec
Casa Noble Hotel

Hotel Museo Spa Casa Santo Domingo

4.5 star property
Barrio de La Concepción, < 0.1 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (1009)
"Great overall stay"
United States
Jose
The price is AU$456
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Museo Spa Casa Santo Domingo

El Convento Boutique Hotel

4.0 star property
Historic Center, 0.4 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (798)
"Great hotel to explore Antigua "
United States
vered
The price is AU$386
includes taxes & fees
21 Dec - 22 Dec
El Convento Boutique Hotel

Hotel Casa Bella

3.0 star property
Historic Center, 0.5 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (258)
"Newly refurbished. Spotless."
United States
Michael
Hotel Casa Bella

Hotel Posada de Don Rodrigo Antigua

3.5 star property
Historic Center, 0.7 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (641)
"Always the best nicest friendliest staff and the location is historic a place to fall in love again and again "
United States
Romilio
The price is AU$328
includes taxes & fees
26 Dec - 27 Dec
Hotel Posada de Don Rodrigo Antigua

All Suite El Marques de Antigua

3.5 star property
0.9 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (294)
"Great location and very clean"
United States
Saul
All Suite El Marques de Antigua

Los Pasos Boutique Hotel & Spa

4.5 star property
0.7 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (1000)
"Great place to stay. "
United States
tania
The price is AU$274
includes taxes & fees
11 Dec - 12 Dec
Los Pasos Boutique Hotel & Spa

Hotel Camino Real Antigua

4.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (1001)
"Beautiful Hotel really centric"
United States
German
The price is AU$552
includes taxes & fees
8 Dec - 9 Dec
Hotel Camino Real Antigua

Hostal Antigueño - Hostel

2.0 star property
0.3 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (30)
"Great place, great people! Highly recommend!"
Canada
Cody
Hostal Antigueño - Hostel

Hotel Casa Bansley

2.5 star property
1.3 km from Casa Santo Domingo Museum
9.8 out of 10, Exceptional, (46)
"Very nice boutique hotel"
United States
Aldo
The price is AU$181
includes taxes & fees
12 Dec - 13 Dec
Hotel Casa Bansley

Mestizo Antigua

4.0 star property
Historic Center, 0.8 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (153)
"The hotel is well situated. The receptionist, Kelyn was amazing, she went out of her way to make my stay comfortable and enjoyable. "
United States
Mercedes
The price is AU$265
includes taxes & fees
5 Jan - 6 Jan 2026
Mestizo Antigua

Good Hotel Antigua

4.0 star property
0.4 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (524)
"Very friendly staff and the room was as expected, clean and cozy. "
United States
Sayda
The price is AU$337
includes taxes & fees
6 Jan - 7 Jan 2026
Good Hotel Antigua

Hotel Posada del Angel

4.0 star property
1 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (279)
"The breakfast on the rooftop where we could watch the volcano erupt was spectacular. Breakfast was delicious and service was top notch. We stayed in the Rose Suite and loved it."
United States
Amelia
Hotel Posada del Angel

Porta Hotel Antigua

4.5 star property
0.8 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (1001)
"Everything about this hotel was fantastic. The bed was so comfortable. "
United States
Raymond
The price is AU$340
includes taxes & fees
9 Dec - 10 Dec
Porta Hotel Antigua

Hotel La Galeria

3.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (259)
"Room was beautiful and staff were all helpful"
Canada
Becky
Hotel La Galeria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Casa Santo Domingo Museum Hotel Reviews

Hotels near other Casa Santo Domingo Museum attractions

Frequently asked questions

What's the area like around Casa Santo Domingo Museum?
Casa Santo Domingo Museum is located in a historic area of Antigua Guatemala known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 499 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Casa Santo Domingo Museum?
Adjacent to Casa Santo Domingo Museum, Hotel Museo Spa Casa Santo Domingo is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 2 restaurants. Other good choices close by include Porta Hotel Antigua and Hotel Camino Real Antigua.
How many hotels are there near Casa Santo Domingo Museum?
Expedia has 499 hotels and other accommodation options within a mile from Casa Santo Domingo Museum.
If I need to cancel the hotel reservation for my stay near Casa Santo Domingo Museum, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best deals available near Casa Santo Domingo Museum.
What can I see and do near Casa Santo Domingo Museum?
You might want to spend some time browsing the exhibits at Antigua Guatemala Colonial Art Museum, Jade Maya Factory and Museum or La Azotea Cultural Center. Explore notable local landmarks like Las Capuchinas Convent, Santa Clara Convent and Santa Catalina Arch. Spend some time exploring the the natural beauty of Central Park, Tanque La Unión and El Reposo Spa.