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Family Hotels & Resorts in Cape Girardeau from AU$119

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Best Cape Girardeau Family Hotels

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is AU$153
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel Cape Girardeau Conference Center

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is AU$150
includes taxes & fees
18 Dec - 19 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1005)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is AU$119
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center

Candlewood Suites Cape Girardeau by IHG

2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (878)
"Clean room, low noise and very comfortable!"
United States
Richard
The price is AU$127
includes taxes & fees
14 Dec - 15 Dec
Candlewood Suites Cape Girardeau by IHG

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau
10.0 out of 10, Exceptional, (148)
"Such a great place and location"
United States
Tracy H.
The price is AU$373
includes taxes & fees
10 Dec - 11 Dec
Serenity South -- Gardens, River-Views, and Refreshing Space

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"Great stay"
United States
Heather
The price is AU$119
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Cape Girardeau West

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (661)
"Great place "
United States
GUY
The price is AU$127
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hotel 7 Inn Anna

2.5 star property
Anna
6.6 out of 10, (217)
"The staff was wonderful"
United States
Donna
The price is AU$153
includes taxes & fees
18 Dec - 19 Dec
Hotel 7 Inn Anna

Beautiful location in the secluded woods

Pomona
10.0 out of 10, Exceptional, (60)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
The price is AU$257
includes taxes & fees
12 Dec - 13 Dec
Beautiful location in the secluded woods

Contemporary Glamping with Native American Appeal

Anna
9.8 out of 10, Exceptional, (155)
"Our 2nd time staying here and it was perfect"
United States
machelle p.
Contemporary Glamping with Native American Appeal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cape Girardeau Hotel Reviews

Frequently asked questions

What's Cape Girardeau like for family-friendly holidays?
You may want to consider the historic destination of Cape Girardeau if you've been thinking about a trip for the whole family. The restaurants here makes this an attractive holiday spot for families. Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is the closest airport, or Cairo, IL (CIR-Cairo Regional), which is located 23.4 mi (37.6 km) from the city centre.
What's the best family accommodation in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other good options for your child-friendly holiday include Pear Tree Inn Cape Girardeau West and Pear Tree Inn Cape Girardeau Near the Medical Center.
When's the best time to book a family-friendly holiday in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.
What's there to see and do with your family in Cape Girardeau?
While you and your family are visiting Cape Girardeau, you may want to explore some child-friendly attractions such as Show Me Center, Cape Splash Family Aquatic Center and The Glenn House. Make sure that you have lots of time for activities such as Cape Girardeau Conservation Nature Center and Lazy L Safari Park.