A calm body of water, a sandy beach, and a forested area in the distance.

Holiday Homes in Cape Girardeau

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Check prices for these dates

In two weeks
16 Oct - 18 Oct
In two months
27 Nov - 29 Nov
In three months
25 Dec - 27 Dec
In four months
22 Jan - 24 Jan

Our top choices for Cape Girardeau holiday homes

A living room with a TV, a fireplace, a sofa, and wall art.

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (58 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AU$158
includes taxes & fees
10 Oct - 11 Oct
Little Blue Cottage on Spanish
A dining area with a table and chairs, a window with blinds, a kitchen with appliances, and a ceiling light fixture.

2. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is AU$259
includes taxes & fees
20 Oct - 21 Oct
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Ground floor of the Euro

3. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is AU$323
includes taxes & fees
5 Oct - 6 Oct
The Little Château | Woodland Escape
Exterior

4. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is AU$330
includes taxes & fees
6 Oct - 7 Oct
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Exterior

5. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is AU$332
includes taxes & fees
2 Oct - 3 Oct
The Little Cape Lofted Cottage | Creek & Nature
A two-story house with a front porch, a small garden, and a white picket fence.

6. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (44 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AU$445
includes taxes & fees
4 Oct - 5 Oct
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
A modern kitchen with a large island, white cabinetry, and a brick accent wall.

7. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is AU$448
includes taxes & fees
5 Oct - 6 Oct
Beautifully Renovated Farmhouse in Jackson, MO
A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

8. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is AU$833
includes taxes & fees
5 Oct - 6 Oct
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
A wooden cabinet with a microwave, coffee maker, and plates.

9. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (26 reviews)
"Comfortable bed which is what we needed. We weren’t there long but is was everything we needed."
United States
Kathy H.
The price is AU$230
includes taxes & fees
4 Oct - 5 Oct
Cozy and Updated Farmhouse with King Suite
A kitchen with wooden cabinets, a countertop, and a window with blinds.

10. Crossview Cottage - Direct view of Bald Knob Cross

Crossview Cottage - Direct view of Bald Knob Cross
Alto Pass
The price is AU$180
includes taxes & fees
5 Oct - 6 Oct
Crossview Cottage - Direct view of Bald Knob Cross
A red barn with a sloped roof, surrounded by a grassy field and trees.

11. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is AU$239
includes taxes & fees
6 Oct - 7 Oct
The Weber Farm - Enjoy a beautiful 100 acre farm!
A brick building with a sign reading "1898 Guesthouse".

12. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (14 reviews)
"Cool renovated property that keeps that old fashioned charm. Spacious living with all the amenities you need for a vacation stay."
United States
Dylan
The price is AU$409
includes taxes & fees
7 Oct - 8 Oct
Stunning 2 bedroom in town, close to Shawnee National Forest
A wooden deck with two white Adirondack chairs and a small round table.

13. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Alto Pass
10.0 out of 10, Exceptional, (5 reviews)
"The house was very welcoming and clean. Very inviting for our short stay. "
United States
brian O.
The price is AU$379
includes taxes & fees
5 Oct - 6 Oct
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
A covered porch with a wooden railing, a table with chairs, and a sofa.

14. Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
10.0 out of 10, Exceptional, (82 reviews)
"This rental was very clean, pet friendly, and definitely secluded. We enjoyed our stay here."
United States
Candi M.
The price is AU$259
includes taxes & fees
6 Oct - 7 Oct
Beautiful location in the secluded woods
A large, two-story house with a wrap-around porch, surrounded by a well-maintained garden with various flowering plants.

15. Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
9.8 out of 10, Exceptional, (19 reviews)
"Everything was beautiful, and although we weren’t there for a long time, enjoyed an Incredible sleep in the most comfortable beds!"
United States
Rachel H.
The price is AU$495
includes taxes & fees
6 Oct - 7 Oct
Magical Victorian near hiking / wine trail
A spacious living room with a brown leather sofa, a dining area with a wooden table and chairs, a kitchen with white cabinets and a central island, and large windows with blinds.

16. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Anna
10.0 out of 10, Exceptional, (12 reviews)
"Clean, attentive host, shops near by, family friendly "
United States
Molly J.
The price is AU$392
includes taxes & fees
13 Oct - 14 Oct
Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Living area

17. Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda

Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda
Makanda
The price is AU$225
includes taxes & fees
5 Oct - 6 Oct
Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda
A spacious living area with a kitchen, a dining table, and comfortable seating.

18. Whole Inn Rental! 5 King Beds, 2 Hot Tubs

Whole Inn Rental! 5 King Beds, 2 Hot Tubs
Cobden
The price is AU$1,181
includes taxes & fees
4 Oct - 5 Oct
Whole Inn Rental! 5 King Beds, 2 Hot Tubs
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

10/10 Excellent
"We’ve been staying at Chip’s house the past two years during the fair! It’s always comfy and cozy! Chip’s fabulous!"
Jeff O. 9-night trip
Posted 11 hours ago
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Find out more about Cape Girardeau

Cape Girardeau Holiday Homes information

Number of reviews
231
Accommodation
65 Holiday Homes
Lowest Price
AU$158
Highest Price
AU$1,181