Cairo Ohio River Bridge traversing over the Ohio River at sunset

Luxury Hotels & Resorts in Cairo from AU$89

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Cairo Luxury Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Cairo

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (288 reviews)
The price is AU$107
includes taxes & fees
10 July - 11 July
Quality Inn Cairo I-57

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
The price is AU$89
includes taxes & fees
18 June - 19 June
La Center Motel

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (416 reviews)
The price is AU$118
includes taxes & fees
17 June - 18 June
The Riverstone Hotel Charleston-Sikeston

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is AU$410
includes taxes & fees
21 June - 22 June
Quiet Country Stay: Modern Home Near Paducah

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (104 reviews)
The price is AU$401
includes taxes & fees
21 June - 22 June
Charming cottage overlooking Lake Acre

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (27 reviews)
The price is AU$282
includes taxes & fees
23 June - 24 June
Peaceful secluded cabin located near Horseshoe Lake

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (641 reviews)
The price is AU$93
includes taxes & fees
12 July - 13 July
Super 8 by Wyndham Charleston/Sikeston East MO

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
The price is AU$336
includes taxes & fees
17 June - 18 June
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
10.0 out of 10, Exceptional, (41 reviews)
The price is AU$201
includes taxes & fees
17 June - 18 June
Cozy cabins on beautiful Horseshoe Lake

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
The price is AU$112
includes taxes & fees
17 June - 18 June
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cairo Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Cairo?
Let Expedia help you arrange your flight to Cairo, IL (CIR-Cairo Regional) airport or Paducah, KY (PAH-Barkley Regional) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay special. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Cairo offers. Cairo has some interesting things to see and do including Mississippi River and Ohio River Valley, so you might want to take in the local sights during your visit.
When can I expect good weather in Cairo?
Planning for the weather is an important factor for making your trip to Cairo a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cairo is 1540 mm.
What's there to see and do in Cairo?
Enjoy all that Cairo has to offer when you visit Mississippi River, Ohio River Valley and Fort Defiance State Park. If you have spare time during your trip, you might want to make a stop at Ballard Wildlife Management Area and Columbus-Belmont State Park.

Explore a world of travel with Expedia