
South Carolina Midlands Fishing Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to AU$2,500 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Fishing South Carolina Midlands Hotels

Hampton Inn & Suites Fort Mill
1520 Carolina Place Drive Fort Mill SC
Stay at this business-friendly hotel in Fort Mill. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

Lake Murray Resort & Marina
101 Sandalwood Drive Leesville SC
Stay at this beach hotel in Leesville. Enjoy free Wi-Fi, free parking and 3 restaurants. Popular attractions Dreher Island State Park and Dreher Island are located ...

Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,001 reviews)
"We have always stayed at the BW Santee on our road trips to Florida. It is getting very worn out and not maintained too well. The toilet in the room was clogged and handle broken when we checked in which it took about an hour to fix. We booked through Expedia for this stay because it was a good bit ..."
Reviewed on 7 Nov 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.











