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Our top choices for South Carolina Midlands hotels

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (579 reviews)
"Great visit to this site...convenient to food, gas, and the staff was so pleasant. Breakfast was very good and I would not hesitate to stay there again"
United States
Cheryl
The price is AU$168
includes taxes & fees
17 May - 18 May
Holiday Inn Express & Suites Latta by IHG

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,637 reviews)
"Very comfortable room and the hotel was close to the Interstate and many good trestaurants."
United States
Charles
The price is AU$102
includes taxes & fees
26 Apr - 27 Apr
Howard Johnson by Wyndham Florence

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
3.0 star property
Hartsville
8.6 out of 10, Excellent, (722 reviews)
"Clean facility with friendly and helpful staff."
United States
Kermit
The price is AU$125
includes taxes & fees
8 May - 9 May
Fairfield Inn by Marriott Hartsville

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (800 reviews)
"Great stay!"
United States
Preston
The price is AU$189
includes taxes & fees
5 May - 6 May
Tru By Hilton Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,441 reviews)
"Location was great for a one night stay over "
Canada
Silvana
The price is AU$116
includes taxes & fees
26 Apr - 27 Apr
Baymont by Wyndham Santee

Hampton Inn Newberry-Opera House

Hampton Inn Newberry-Opera House
2.5 star property
Newberry
8.8 out of 10, Excellent, (828 reviews)
"Great location."
United States
Thomas
The price is AU$187
includes taxes & fees
11 May - 12 May
Hampton Inn Newberry-Opera House

Best Western Rock Hill

Best Western Rock Hill
2.5 star property
Rock Hill
8.6 out of 10, Excellent, (1,000 reviews)
"Breakfast was very good. Parking was convenient and secure. Room was clean and comfortable."
United States
Don
The price is AU$113
includes taxes & fees
4 May - 5 May
Best Western Rock Hill

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.6 out of 10, Excellent, (102 reviews)
"Employees were very helpful and friendly. Great stay!"
United States
Jerry
The price is AU$161
includes taxes & fees
18 May - 19 May
Quality Inn & Suites Florence Civic Center

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
3.0 star property
Columbia
8.0 out of 10, Very good, (1,011 reviews)
"Free parking and breakfast was exceptional!! "
United States
abla
The price is AU$135
includes taxes & fees
24 May - 25 May
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel
3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (734 reviews)
"Near to historic district. "
United States
Sandra
The price is AU$183
includes taxes & fees
17 May - 18 May
Inn on the Square, an Ascend Collection Hotel

Holiday Inn Express Richburg by IHG

Holiday Inn Express Richburg by IHG
2.5 star property
Richburg
9.2 out of 10, Wonderful, (675 reviews)
"It was clean and beds comfortable. Breakfast nice"
United States
Paul
The price is AU$163
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express Richburg by IHG

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,000 reviews)
"Great stay! "
Canada
Julie
The price is AU$177
includes taxes & fees
21 May - 22 May
Tru by Hilton Orangeburg

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,000 reviews)
"Excellent hotel, clean rooms, great breakfast "
United States
Roberta
The price is AU$215
includes taxes & fees
4 May - 5 May
Fairfield Inn & Suites by Marriott Santee

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison
3.0 star property
Columbia
8.8 out of 10, Excellent, (2,024 reviews)
"Everything was nice,clean and staff was great"
United States
Dan
The price is AU$159
includes taxes & fees
11 May - 12 May
Hilton Garden Inn Columbia/Harbison

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
The price is AU$198
includes taxes & fees
6 May - 7 May
Best Western Plus Santee Inn

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
"Very clean & the breakfast staff was very courteous."
United States
Helen
The price is AU$210
includes taxes & fees
19 May - 20 May
Hampton Inn Santee-I-95

Hotel Everett

Hotel Everett
4.0 star property
Winnsboro
The price is AU$270
includes taxes & fees
6 May - 7 May
Hotel Everett

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very good, (72 reviews)
"Wonderful staff and very clean room and facilities , "
United States
catherine
The price is AU$145
includes taxes & fees
20 May - 21 May
Spark by Hilton Florence North I-95, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,263 reviews)
"This is a pretty good hotel, clean and quiet. The breakfast was fine. I have stayed here before and will return."
United States
Avrum
The price is AU$140
includes taxes & fees
24 May - 25 May
Park Inn by Radisson Florence, SC

Deluxe Inn York

Deluxe Inn York
2.0 star property
York
The price is AU$119
includes taxes & fees
27 Apr - 28 Apr
Deluxe Inn York
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in South Carolina Midlands

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With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

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