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Top flight + Adventure hotel deals in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Amérian Portal del Iguazú Hotel

AU$681

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

8.6/10 Excellent! (388 reviews)

Instalaciones buenas y atención del personal muy amable

Reviewed on 20 Feb 2026

Gran Melia Iguazú

Save 100% on your flight

AU$1,018

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9.2/10 Wonderful! (1,002 reviews)

Wonderful stay in the park Hike to Iguazu falls from hotel Amazing breakfast and bbq Pool was much needed with poolside service

Reviewed on 15 Mar 2026

Loi Suites Iguazú Hotel

AU$889

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9.2/10 Wonderful! (1,003 reviews)

This hotel was perfection, from the moment we entered we were in paradise

Reviewed on 12 Mar 2026

Falls Iguazú Hotel & Spa

AU$769

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9.2/10 Wonderful! (473 reviews)

Really enjoyed the pool. Perfect swimming temperature with lots of shady places to sit. Did NOT enjoy the techno synthesized music on the loud speakers. Staff were outstanding. Food was good, not great.

Reviewed on 15 Mar 2026

Iguazu Grand Resort Spa & Casino

AU$850

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9/10 Wonderful! (626 reviews)

The staff and amenities were amazing. The rooms large and spacious.

Reviewed on 15 Mar 2026

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See all available trips from Columbus to Mesopotamia

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5* Adventure holidays in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Falls Iguazú Hotel & Spa

AU$769

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9.2/10 Wonderful! (473 reviews)

Really enjoyed the pool. Perfect swimming temperature with lots of shady places to sit. Did NOT enjoy the techno synthesized music on the loud speakers. Staff were outstanding. Food was good, not great.

Reviewed on 15 Mar 2026

Gran Melia Iguazú

Save 100% on your flight

AU$1,018

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9.2/10 Wonderful! (1,002 reviews)

Wonderful stay in the park Hike to Iguazu falls from hotel Amazing breakfast and bbq Pool was much needed with poolside service

Reviewed on 15 Mar 2026

Loi Suites Iguazú Hotel

AU$889

per person

18 May - 20 May

found 22 hours ago

Return direct flight included

Curitiba (CWB) to Iguazu (IGR)

9.2/10 Wonderful! (1,003 reviews)

This hotel was perfection, from the moment we entered we were in paradise

Reviewed on 12 Mar 2026

Don't see what you're looking for?

See all available trips from Columbus to Mesopotamia

View all trips

Top Adventure Mesopotamia Hotels

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

9/10 Wonderful! (633 reviews)

The staff and amenities were amazing. The rooms large and spacious.

Reviewed on 15 Mar 2026

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property condition ...

9.8/10 Exceptional! (1,003 reviews)

You go here for the views of course. The common areas are beautiful. The rooms are 3 star - not 5. They are worse than a premier inn or a Hampton room - small, shabby and dated. The amenities are not as you’d expect of a 5 star. Not even a plug socket on one side of the bed. The pictures are fixed ...

Reviewed on 13 Mar 2026

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

9.2/10 Wonderful! (1,002 reviews)

Wonderful stay in the park Hike to Iguazu falls from hotel Amazing breakfast and bbq Pool was much needed with poolside service

Reviewed on 15 Mar 2026

See all 513 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.