Mesopotamia Adventure Holidays 2026

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Top Adventure Mesopotamia Hotels

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property condition ...

10/10 Exceptional! (1,013 reviews)

"Excellent location inside the national park. Beautiful old school hotel"

Reviewed on 8 Aug 2026

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

9.4/10 Exceptional! (1,009 reviews)

"Exceptional property inside the park ! An absolute gem"

Reviewed on 9 Aug 2026

See all 530 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.