Mesopotamia Holidays

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Your Mesopotamia Holiday

When you long for adventure, book a Mesopotamia holiday package. Get set to enjoy culture, nature, festivals, and much more in this vibrant destination. A trip to Mesopotamia wouldn't be complete without getting to some of its leading cities, starting with Corrientes. Two of the top attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. Concordia is another favourite with Mesopotamia travellers. Visitors to this exciting city love Termas Del Ayui and Concordia Speedway. Whether you're travelling on a shoestring or want to splurge, Expedia are here to help you customise your next Mesopotamia holiday.

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Mesopotamia Holiday

Mesopotamia Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Ministro Pistarini Intl. Airport (EZE)
Top Sights
Termas De Colón, Termas Del Ayui and Termas Concepcion Entrerios

Our pick of the best Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is AU$194 per night from 5 Dec to 6 Dec
AU$194
5 Dec - 6 Dec
10/10 Exceptional! (3 reviews)
Very nice hotel

Reviewed on 9 Nov 2025

Marriott Corrientes Hotel
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

2.5 out of 5
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
The price is AU$52 per night from 24 Nov to 25 Nov
AU$52
24 Nov - 25 Nov
7.6/10 Good! (64 reviews)
Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice.

Reviewed on 2 Jan 2025

O2 Hotel Gualeguaychú
La Casona de Susana

La Casona de Susana

3 out of 5
3 de Febrero 448 Colon Entre Rios
The price is AU$74 per night from 3 Dec to 4 Dec
AU$74
3 Dec - 4 Dec
La propietaria respeta el precio acordado. En verano si usás más de 8 horas por día el aire acondicionado te cobran un plus.

Reviewed on 13 Mar 2023

La Casona de Susana
See all 492 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Mesopotamia

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.

Basilica Nuestra Senora De Itati

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travellers to Mesopotamia during the COVID-19 outbreak?
If it's your first time travelling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.