Mesopotamia Holidays

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Your Mesopotamia Holiday

Known for its diversity and cultural experiences, Mesopotamia promises a truly unforgettable travel adventure. Book one of our Mesopotamia holiday packages and spend a few exciting weeks or more discovering all the cool things this destination has to offer. The best and easiest way to organise your trip to Mesopotamia is to start with its leading cities, which include Gualeguaychú, Parana and Colon. Find some travel buddies and start packing, because your Mesopotamia holiday is just clicks away with Expedia.

Mesopotamia Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Ministro Pistarini Intl. Airport (EZE)
Top Sights
Termas De Colón, Termas Del Ayui and Termas Concepcion Entrerios

Our pick of the best Mesopotamia Hotel Deals

O2 Hotel Gualeguaychú
O2 Hotel Gualeguaychú
2.5 out of 5
115 3 de Febrero, Gualeguaychú, Entre Ríos
The price is AU$66 per night from 21 Apr to 22 Apr
AU$66
per night
21 Apr - 22 Apr
7.2/10 Good! (37 reviews)
"Newly remodeled. Simple (no TV). Clean. Good A/C. Basic breakfast. Friendly staff. Nice rooms. Wifi was non-existent in the room on the 5th floor (despite the front desk resetting their routers), but great everywhere else. The place is in a nice and safe area with nearby restaurants. It’s not 10 ..."

Reviewed on 12 Feb. 2024

O2 Hotel Gualeguaychú
Hathor Concordia
Hathor Concordia
3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
The price is AU$106 per night from 1 May to 2 May
AU$106
per night
1 May - 2 May
8.4/10 Very Good! (302 reviews)
"The hotel was very clean and quiet. It was a great stop in between Buenos Aires and Puerto Iguazu!! The restaurant had delicious food and great service and a nice selection of wine and beer. The front desk was very welcoming and answered all questions. Also the room itself was clean and had safety ..."

Reviewed on 14 Mar. 2024

Hathor Concordia
Club Valle Termal Resort
Club Valle Termal Resort
3 out of 5
Hnas. Bentancourt esq. Coronel Salas, Federacion, Entre Rios
The price is AU$69 per night from 24 Apr to 25 Apr
AU$69
per night
24 Apr - 25 Apr
Club Valle Termal Resort
See all 405 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays

All Inclusive Holidays

All Inclusive Holidays
beach holidays

Beach Holidays

Beach Holidays
family friendly holidays

Family Friendly Holidays

Family Friendly Holidays

Frequently asked questions

How much does a Mesopotamia holiday package cost?
Maybe less than you might think — from only , actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia holiday package with Expedia is a great way to save. We offer more than 550 partner airlines and 1 000 000 hotels across the globe. With such a broad range to choose from, you’ll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travellers.
How far in advance should I book my Mesopotamia holiday?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it’s generally a good idea to book ahead of time, lucky travellers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you’ve made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That’s also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it’s not just hotels. Expedia has all types of properties, including holiday homes such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia holiday package?
Yes, and with over 550 airlines to select from worldwide, you’re not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia holiday package?
Don’t worry if you’re rethinking your Mesopotamia holiday package — you can cancel or amend your booking. And if you’ve booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realise life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you’re ready to make changes, we’ll take care of it.

Discover the most popular places to visit in Mesopotamia

Image for Iberá Provincial Reserve

Iberá Provincial Reserve

Explore the great outdoors with a trip to Iberá Provincial Reserve, a popular green space in Colonia Carlos Pellegrini. Wander the forests and marina while you're in the area.

Iberá Provincial Reserve
Image for National Flag Memorial

National Flag Memorial

Find out about the history of Rosario when you take a trip to National Flag Memorial. Stroll along the marina or visit the monuments while you're in the area.

National Flag Memorial
Image for El Palmar National Park

El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

El Palmar National Park

More holiday ideas

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.