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Top flight + Adults Only hotel deals in Florida Keys

Price found within the past 48 hours. Click for updated prices.

Southernmost Beach Resort and Guesthouses

Old Town Key West

AU$1,619

per person

19 June - 21 June

found 1 day ago

Return direct flight included

Syracuse (SYR) to Key West (EYW)

8.8/10 Excellent! (3,272 reviews)

High prices for water in room when you can go to store down Duvall and get it for half the price. Found a roach in my room the last day. Staff great!!!! Resort beautiful!!!

Reviewed on 17 May 2026

The Marker Key West Harbor Resort

Key West Historic District

AU$1,751

per person

19 June - 21 June

found 1 day ago

Return direct flight included

Syracuse (SYR) to Key West (EYW)

9.2/10 Wonderful! (1,003 reviews)

Rooms were not cleaned until 5pm….sheets not changed. One towel per person per day to shower. Bed was comfortable but sheets were hard. Just ok….but clean. Room size was very good.

Reviewed on 15 May 2026

Parrot Key Hotel & Villas

Northside Resort

AU$1,885

per person

19 June - 21 June

found 1 day ago

Return direct flight included

Syracuse (SYR) to Key West (EYW)

9/10 Wonderful! (1,382 reviews)

Fabulous property. Plenty around the area to do things. Free shuttle was excellent. Go get some scooters for $45.00 a day and ride around the downtown and surrounding areas. Too much fun! We will be back!

Reviewed on 16 May 2026

Southernmost House - Adult Exclusive

Old Town Key West

AU$1,684

per person

19 June - 21 June

found 1 day ago

Return direct flight included

Syracuse (SYR) to Key West (EYW)

9.4/10 Exceptional! (1,006 reviews)

Beautiful property. Excellent service.

Reviewed on 15 May 2026

Pier House Resort & Spa

Key West Historic District

AU$1,835

per person

19 June - 21 June

found 1 day ago

Return direct flight included

Syracuse (SYR) to Key West (EYW)

9/10 Wonderful! (1,103 reviews)

This hotel was by far one of the best on the island. The pool and the little beach they have are amazing! Every staff member we encountered was friendly and helpful. The room was spacious and we got really lucky to have a sunset view room.

Reviewed on 16 May 2026

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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...

8.4/10 Very Good! (1,360 reviews)

The space was nice and convenient but the desk check-in and check out worker was aloof and not very communicative.

Reviewed on 18 May 2026

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge) and a garden. Our guests praise the breakfast and the pool in their ...

9.2/10 Wonderful! (1,008 reviews)

Everything was perfect.

Reviewed on 18 May 2026

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free Wi-Fi and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...

9.2/10 Wonderful! (1,150 reviews)

We moved from a tropical king to a king suite. This room did not have any seating however, our room faced the pool which I loved and enjoyed. The suite was larger with seating inside and on the porch. Will definitely come back. A shout out to Greg and Larry for their great hospitality!

Reviewed on 17 May 2026

See all 8,285 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.