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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...

8.2/10 Very Good! (1,284 reviews)

Rude staff, The lady at the receptionist desk didnt even say hello welcome. She just gave me an ugly stare and said last name....The rest of the staff looked angry and tired....Maybe switch up employees moving forward it woukd be a better experience....

Reviewed on 27 Mar 2026

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge) and daily housekeeping. Our guests praise the breakfast and the pool ...

9.2/10 Wonderful! (1,001 reviews)

Wonderful property. Great location. Feels quiet and secluded. We loved the breakfast and the happy hour.

Reviewed on 28 Mar 2026

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free Wi-Fi and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...

9/10 Wonderful! (1,127 reviews)

Breakfast was very good. Staff was excellent and quick to help with anything we needed. Property and room both needed maintenance. Bed wasn’t comfortably.

Reviewed on 27 Mar 2026

See all 8,108 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.