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Cheap Flights from Santiago (SCL) to Santa Cruz (VVI)

View AU$222 flight on Sat, 3 Oct 2026Opens in a new window

Flight 1

Popular airlines from Santiago Intl. Airport (SCL) to Santa Cruz (VVI-Viru Viru Intl.)

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Cheap Flights from Santiago (SCL) to Santa Cruz (VVI)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Boliviana De Aviacion
Sat, 26 Sept - Fri, 2 Oct
SCL
Santiago
VVI
Santa Cruz
AU$466 Return, found 9 hours ago
AU$466
Return
found 9 hours ago
Select Boliviana De Aviacion flight, departing Sat, 26 Sept from Santiago to Santa Cruz, returning Fri, 2 Oct, priced at AU$466 found 9 hours ago
Boliviana De Aviacion
Sat, 6 Mar - Tue, 16 Mar
SCL
Santiago
VVI
Santa Cruz
AU$495 Return, found 2 days ago
AU$495
Return
found 2 days ago
Select Boliviana De Aviacion flight, departing Sat, 6 Mar from Santiago to Santa Cruz, returning Tue, 16 Mar, priced at AU$495 found 2 days ago
Boliviana De Aviacion
Wed, 17 Feb - Tue, 2 Mar
SCL
Santiago
VVI
Santa Cruz
AU$525 Return, found 2 days ago
AU$525
Return
found 2 days ago
Select Boliviana De Aviacion flight, departing Wed, 17 Feb from Santiago to Santa Cruz, returning Tue, 2 Mar, priced at AU$525 found 2 days ago
Boliviana De Aviacion
Wed, 3 Feb - Tue, 16 Feb
SCL
Santiago
VVI
Santa Cruz
AU$555 Return, found 2 days ago
AU$555
Return
found 2 days ago
Select Boliviana De Aviacion flight, departing Wed, 3 Feb from Santiago to Santa Cruz, returning Tue, 16 Feb, priced at AU$555 found 2 days ago
Aerolineas Argentinas
Mon, 15 Feb - Tue, 2 Mar
SCL
Santiago
VVI
Santa Cruz
AU$594 Return, found 2 days ago
AU$594
Return
found 2 days ago
Select Aerolineas Argentinas flight, departing Mon, 15 Feb from Santiago to Santa Cruz, returning Tue, 2 Mar, priced at AU$594 found 2 days ago
Boliviana De Aviacion
Sat, 6 Mar - Sat, 20 Mar
SCL
Santiago
VVI
Santa Cruz
AU$600 Return, found 2 days ago
AU$600
Return
found 2 days ago
Select Boliviana De Aviacion flight, departing Sat, 6 Mar from Santiago to Santa Cruz, returning Sat, 20 Mar, priced at AU$600 found 2 days ago
Aerolineas Argentinas
Mon, 29 Mar - Tue, 13 Apr
SCL
Santiago
VVI
Santa Cruz
AU$608 Return, found 2 days ago
AU$608
Return
found 2 days ago
Select Aerolineas Argentinas flight, departing Mon, 29 Mar from Santiago to Santa Cruz, returning Tue, 13 Apr, priced at AU$608 found 2 days ago
LATAM Airlines Group
Thu, 24 Sept - Fri, 2 Oct
SCL
Santiago
VVI
Santa Cruz
AU$627 Return, found 9 hours ago
AU$627
Return
found 9 hours ago
Select LATAM Airlines Group flight, departing Thu, 24 Sept from Santiago to Santa Cruz, returning Fri, 2 Oct, priced at AU$627 found 9 hours ago
avianca
Mon, 15 Feb - Wed, 3 Mar
SCL
Santiago
VVI
Santa Cruz
AU$807 Return, found 2 days ago
AU$807
Return
found 2 days ago
Select avianca flight, departing Mon, 15 Feb from Santiago to Santa Cruz, returning Wed, 3 Mar, priced at AU$807 found 2 days ago
GOL Linhas Aereas S.A.
Sun, 23 Aug - Tue, 29 Sept
SCL
Santiago
VVI
Santa Cruz
AU$1,387 Return, found 9 hours ago
AU$1,387
Return
found 9 hours ago
Select GOL Linhas Aereas S.A. flight, departing Sun, 23 Aug from Santiago to Santa Cruz, returning Tue, 29 Sept, priced at AU$1,387 found 9 hours ago

Frequently asked questions

How much does a flight from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) cost?
You can find one-way and return flights from SCL to VVI with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when SCL to VVI ticket fares go up or down.
What is the cheapest month to fly from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
The cheapest months to fly from SCL to VVI are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
There are 2 airlines that offer direct flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.).
  • Boliviana De Aviacion operates 7 direct flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) every week.
  • LATAM Airlines Group operates 7 direct flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) every week.
How do I find cheap flights from Santiago (SCL) to Santa Cruz (VVI)?
To find a cheap flight from Santiago (SCL) to Santa Cruz (VVI), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
The best airline to fly with from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) will differ from traveler to traveler. If you like to fly early, Boliviana De Aviacion offers early morning flights. If price is the most important factor, Boliviana De Aviacion typically offers the lowest fares. LATAM Airlines Group offers the most daily flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
There are approximately 14 connecting flights per day from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.). Some common connection points include Jorge Chavez Intl. (LIM), El Alto Intl. (LPB), and Aeroparque Jorge Newbery (AEP).
What is the earliest flight from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
The earliest flight from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) typically departs around 12:30 AM local time. This flight is operated by Avianca. This is a seasonal service, active in April, May, and July. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
You'll typically find the most flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) on a Friday, with around 10 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include LATAM Airlines Group, Avianca, and Aerolineas Argentinas. Fridays offer notably more flight options compared to other days of the week, making it a good day to consider if you need more flexibility.
What are the most popular departure times for flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
The most popular departure times for flights from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) are in the evening, from 6pm to 9pm. Many major carriers, including LATAM Airlines Group and Aerolineas Argentinas, offer flights during this window. Many travellers prefer this time as it allows for a full day of activities before heading to the airport.
How long does it take to fly from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
A direct flight from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.) typically takes around 3 hours 18 minutes. This route covers a distance of approximately 1,910 kilometres. If you opt for a flight with one stop, your travel time will be longer, usually around 8 hours 48 minutes. Flights with two or more stops generally take about 13 hours 48 minutes. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your journey.
Can you fly business or first class from Santiago (SCL-Arturo Merino Benitez) to Santa Cruz (VVI-Viru Viru Intl.)?
You can fly business class between SCL and VVI. Airlines that offer business class service on this route include:

  • Avianca

How do I earn miles on a Santiago (SCL) to Santa Cruz (VVI) flight with Expedia?
It's easy to earn miles on a Santiago (SCL) to Santa Cruz (VVI) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santa Cruz (VVI) from Santiago (SCL)?
If you're planning to travel to Santa Cruz from Arturo Merino Benitez (SCL), you can fly directly into Viru Viru Intl. (VVI). Some flights may connect through major hubs like Aeroparque Jorge Newbery (AEP), Alejandro Velasco Astete Intl. (CUZ), or El Alto Intl. (LPB) before reaching Santa Cruz. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Santiago (SCL) to Santa Cruz (VVI) at the last minute?
Typically, booking a last minute flight from Santiago (SCL) to Santa Cruz (VVI) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Santiago (SCL) to Santa Cruz (VVI) flight and hotel package?
Securing a Santiago (SCL) to Santa Cruz (VVI) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Santiago (SCL) to Santa Cruz (VVI)?
If you booked your Santiago (SCL) to Santa Cruz (VVI) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
Viru Viru Intl.
Airlines serving
LATAM Airlines Group
Return price
AU$466
Distance
1899 km
Average flight time
3 hours 49 mins

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Your quick guide to flights from Santiago to Santa Cruz

Pick up great flights from Santiago to Santa Cruz

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Santiago to Santa Cruz. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Santiago to Santa Cruz that take around hours.

Find cheap flights from Santiago to Santa Cruz

From the great flight deals with prices currently ranging from AU$466 to AU$1,387, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Santiago to Santa Cruz around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santa Cruz is normally in September.

Reasons to book your flight from Santiago to Santa Cruz with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Santiago to Santa Cruz across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santa Cruz right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Santiago to Santa Cruz
*Available to Expedia members.