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Cheap Flights from Santiago (SCL) to Guayaquil (GYE)

View AU$271 flight on Fri, 4 Dec 2026Opens in a new window

Flight 1

Popular airlines from Santiago Intl. Airport (SCL) to Jose Joaquin de Olmedo Intl. Airport (GYE)

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Cheap Flights from Santiago (SCL) to Guayaquil (GYE)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$533 Return, found 4 days ago
AU$533
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$533 found 4 days ago
LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$540 Return, found 4 days ago
AU$540
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$540 found 4 days ago
LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$548 Return, found 4 days ago
AU$548
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$548 found 4 days ago
LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$563 Return, found 4 days ago
AU$563
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$563 found 4 days ago
avianca
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$568 Return, found 4 days ago
AU$568
Return
found 4 days ago
Select avianca flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$568 found 4 days ago
LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$570 Return, found 4 days ago
AU$570
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$570 found 4 days ago
avianca
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$576 Return, found 4 days ago
AU$576
Return
found 4 days ago
Select avianca flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$576 found 4 days ago
LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$580 Return, found 4 days ago
AU$580
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$580 found 4 days ago
LATAM Airlines Group
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$588 Return, found 4 days ago
AU$588
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$588 found 4 days ago
Copa
Thu, 13 Aug - Wed, 19 Aug
SCL
Santiago
GYE
Guayaquil
AU$599 Return, found 4 days ago
AU$599
Return
found 4 days ago
Select Copa flight, departing Thu, 13 Aug from Santiago to Guayaquil, returning Wed, 19 Aug, priced at AU$599 found 4 days ago

Frequently asked questions

How much does a flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) cost?
You can find one-way and return flights from SCL to GYE with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when SCL to GYE ticket fares go up or down.
What is the cheapest month to fly from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
October is typically the cheapest month to fly from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.), with average return fares around AU$716. October sees lower prices because it falls after the peak travel season, when demand drops and airlines compete for bookings. July and November are also good months to find deals on this route.
Which airlines fly direct from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
Only one airline offers direct flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.). LATAM Airlines Group operates 7 direct flights from SCL to GYE every week.
What is the cheapest airline that flies from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
LATAM Airlines Group also offers one of the cheapest connecting return flights with a layover in Jorge Chavez Intl. (LIM), starting from around AU$566. LATAM Airlines Group is one of the cheapest airlines offering nonstop return flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.), with tickets starting from around AU$608 for flights that can be booked for departure within the next year. These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
To find a cheap flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The best airline to fly with from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) will differ from traveler to traveler. If you like to fly early, LATAM Airlines Group offers early morning flights. If price is the most important factor, LATAM Airlines Group typically offers the lowest fares. Copa offers the most daily flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The best time to fly from Santiago (SCL) to Guayaquil (GYE) can vary. You'll find the cheapest flights in October or July, with average prices around AU$716 for a return flight. While these months offer great value, the most popular times to travel are typically August and March, meaning you'll have plenty of flight options and schedules to choose from. If you're flexible, you might find a good balance by looking for deals in the shoulder seasons around these times.
How many flights per day from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
There is 1 nonstop flight per day from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.). For even more choices, look at flights that include layovers, as there are around 23 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), Tocumen Intl. (PTY), and Jorge Chavez Intl. (LIM).
What is the earliest flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The earliest flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) typically departs around 12:00 AM local time. This service is operated by Copa and is seasonal, active only in May. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
You'll generally find the most flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) on a Tuesday, with around 18 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include LATAM Airlines Group, Copa, and Avianca. Flight schedules are quite consistent throughout the week, so you'll have plenty of choices no matter which day you choose to fly.
What are the most popular departure times for flights from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
The most popular departure times for flights from Santiago (SCL) to Guayaquil (GYE) are in the early morning, from midnight to 3am. Many major carriers, including Copa, LATAM Airlines Group and Avianca, offer flights during this window. Many travellers prefer these times as they can arrive at their destination early in the day, giving them more time to settle in or start their activities.
How long does it take to fly from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
A nonstop flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) typically takes around 5 hours 15 minutes, covering a distance of approximately 3,602 kilometres. If you opt for a one-stop flight, your travel time will be longer, usually around 8 hours. Flights with two or more stops generally take about 12 hours. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your journey.
Can you fly business or first class from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
Yes, you can fly business class between SCL and GYE. You can fly business class with Avianca and Copa.
How do I earn miles on a Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight with Expedia?
It's easy to earn miles on a Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Guayaquil (GYE) from Santiago (SCL)?
If you're planning to travel to Guayaquil from Arturo Merino Benitez (SCL), you can fly directly into Jose Joaquin de Olmedo Intl. (GYE). Some flights may connect through major hubs like El Dorado Intl. (BOG), Jorge Chavez Intl. (LIM), or Aeroparque Jorge Newbery (AEP) before reaching Guayaquil. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) at the last minute?
Typically, booking a last minute flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight and hotel package?
Securing a Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.)?
If you booked your Santiago (SCL-Arturo Merino Benitez) to Guayaquil (GYE-Jose Joaquin de Olmedo Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
Copa, LATAM Airlines Group, avianca
Return price
AU$532
Distance
3580 km
Average flight time
6 hours 18 mins

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Your quick guide to flights from Santiago to Guayaquil

Pick up great flights from Santiago to Guayaquil

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Santiago to Guayaquil. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Santiago to Guayaquil that take around hours.

Find cheap flights from Santiago to Guayaquil

From the great flight deals with prices currently ranging from AU$533 to AU$599, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Santiago to Guayaquil around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Guayaquil is normally in August.

Reasons to book your flight from Santiago to Guayaquil with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Santiago to Guayaquil across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Guayaquil right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Santiago to Guayaquil

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