Cheap Flights from Madrid (MAD) to Panama City (PTY)

View AU$565 flight on Wed, 20 May 2026Opens in a new window

Flight 1

Popular airlines from Adolfo Suarez Madrid-Barajas Airport (MAD) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Madrid (MAD) to Panama City (PTY)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Mon, 18 Jan - Sat, 30 Jan
MAD
Madrid
PTY
Panama City
AU$1,144 Return, found 3 hours ago
AU$1,144
Return
found 3 hours ago
Select avianca flight, departing Mon, 18 Jan from Madrid to Panama City, returning Sat, 30 Jan, priced at AU$1,144 found 3 hours ago
Delta
Mon, 18 Jan - Sat, 30 Jan
MAD
Madrid
PTY
Panama City
AU$1,152 Return, found 3 hours ago
AU$1,152
Return
found 3 hours ago
Select Delta flight, departing Mon, 18 Jan from Madrid to Panama City, returning Sat, 30 Jan, priced at AU$1,152 found 3 hours ago
Air Europa
Mon, 18 Jan - Sat, 30 Jan
MAD
Madrid
PTY
Panama City
AU$1,173 Return, found 3 hours ago
AU$1,173
Return
found 3 hours ago
Select Air Europa flight, departing Mon, 18 Jan from Madrid to Panama City, returning Sat, 30 Jan, priced at AU$1,173 found 3 hours ago
Air Europa
Wed, 20 May - Wed, 27 May
MAD
Madrid
PTY
Panama City
AU$1,197 Return, found 12 hours ago
AU$1,197
Return
found 12 hours ago
Select Air Europa flight, departing Wed, 20 May from Madrid to Panama City, returning Wed, 27 May, priced at AU$1,197 found 12 hours ago
Delta
Mon, 18 Jan - Sat, 30 Jan
MAD
Madrid
PTY
Panama City
AU$1,233 Return, found 3 hours ago
AU$1,233
Return
found 3 hours ago
Select Delta flight, departing Mon, 18 Jan from Madrid to Panama City, returning Sat, 30 Jan, priced at AU$1,233 found 3 hours ago
Air Europa
Wed, 20 May - Fri, 22 May
MAD
Madrid
PTY
Panama City
AU$1,254 Return, found 2 hours ago
AU$1,254
Return
found 2 hours ago
Select Air Europa flight, departing Wed, 20 May from Madrid to Panama City, returning Fri, 22 May, priced at AU$1,254 found 2 hours ago
American Airlines
Mon, 18 Jan - Sat, 30 Jan
MAD
Madrid
PTY
Panama City
AU$1,302 Return, found 3 hours ago
AU$1,302
Return
found 3 hours ago
Select American Airlines flight, departing Mon, 18 Jan from Madrid to Panama City, returning Sat, 30 Jan, priced at AU$1,302 found 3 hours ago
American Airlines
Mon, 5 Oct - Mon, 19 Oct
MAD
Madrid
PTY
Panama City
AU$1,309 Return, found 1 day ago
AU$1,309
Return
found 1 day ago
Select American Airlines flight, departing Mon, 5 Oct from Madrid to Panama City, returning Mon, 19 Oct, priced at AU$1,309 found 1 day ago
Turkish Airlines
Mon, 5 Oct - Mon, 19 Oct
MAD
Madrid
PTY
Panama City
AU$1,314 Return, found 1 day ago
AU$1,314
Return
found 1 day ago
Select Turkish Airlines flight, departing Mon, 5 Oct from Madrid to Panama City, returning Mon, 19 Oct, priced at AU$1,314 found 1 day ago
avianca
Mon, 18 Jan - Sat, 30 Jan
MAD
Madrid
PTY
Panama City
AU$1,324 Return, found 3 hours ago
AU$1,324
Return
found 3 hours ago
Select avianca flight, departing Mon, 18 Jan from Madrid to Panama City, returning Sat, 30 Jan, priced at AU$1,324 found 3 hours ago

Frequently asked questions

How much does a flight from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) cost?
One-way flights typically cost between £425 and £1,541 and return flights often range between £835 and £3,690. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
May is typically the cheapest month to fly from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.), with average return fares of approximately £655. This is about 24% lower than the average price throughout the year. May often sees lower prices as it's outside of peak holiday seasons, leading to reduced demand. Other cheap months to fly from Madrid to Panama City include February and October.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
Enter MAD to PTY and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
To find a cheap flight from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
The best airline to fly with from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) will differ from traveller to traveller. If you like to fly early, IB offers early morning flights. If price is the most important factor, IB typically offers the lowest fares. AV offers the most daily flights from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
When planning your trip from Madrid (MAD) to Panama City (PTY), you'll find that May and February are typically the cheapest months to fly. While these months offer the best value, April and December are the most popular times to travel, meaning you'll have plenty of flight options. To get the best of both worlds, consider flying in May or February for a good balance of price and availability, based on booking data from the past year.*Prices based on flights available on Expedia in the last year.
How many flights per day from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
There are approximately 1 nonstop flight per day from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.). For even more choice, look at flights that include layovers, as you'll find around 71 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), Jose Maria Cordova Intl. (MDE), and Roissy-Charles de Gaulle (CDG).
What is the earliest flight from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
The earliest flight from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) typically departs at approximately 12:10 AM local time. This service is operated by Iberia and Avianca. This is a seasonal service active in April, May, and July. An early departure like this can help you maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
You'll typically find the most flights from Adolfo Suárez Madrid-Barajas (MAD) to Tocumen Intl. (PTY) on a Thursday, with around 34 flights available. This gives you a good selection for your travel plans. Major airlines on this route include Iberia, Avianca, and Air Europa.
What are the most popular departure times for flights from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
The most popular departure times for flights from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) are in the afternoon, from 3pm to 6pm. About 44% of passengers prefer this time. Many major carriers, including Air Europa and Avianca, offer flights during this window. This timing works well for many travelers as it allows for a full morning in Madrid before your flight, and you'll arrive in Panama City in the evening.
How long does it take to fly from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
Direct flights from MAD to PTY usually take about 10 hours 30 minutes, traveling roughly 5,069 miles. If you opt for a connecting flight, expect to add around 5 hours 50 minutes to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
Select the "Business class" and "First class" filters when looking for MAD to PTY flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) flight with Expedia?
It's easy to earn miles on a Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Panama City from Adolfo Suarez Madrid-Barajas (MAD)?
From Adolfo Suarez Madrid-Barajas (MAD), you can fly into Northwest Florida Beaches Intl. (ECP) and Tocumen Intl. (PTY) in Panama City. Some flights may connect through major hubs like Logan Intl. (BOS), John F. Kennedy Intl. (JFK), Liberty Intl. (EWR) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) at the last minute?
Typically, booking a last minute flight from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) flight and hotel package?
Securing a Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.)?
If you booked your Madrid (MAD-Adolfo Suárez Madrid-Barajas) to Panama City (PTY-Tocumen Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Adolfo Suárez Madrid-Barajas
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, Air Europa, Air France, American Airlines, Delta, Emirates, Iberia, KLM, Turkish Airlines, United, avianca
Return price
AU$1,143
Distance
8109 km
Average flight time
3 hours 50 mins

Book with confidence

Your quick guide to flights from Madrid to Panama City

Pick up great flights from Madrid to Panama City

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Madrid to Panama City. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Madrid to Panama City that take around hours.

Find cheap flights from Madrid to Panama City

From the great flight deals with prices currently ranging from AU$1,144 to AU$1,324, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Madrid to Panama City around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Panama City is normally in January.

Reasons to book your flight from Madrid to Panama City with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Madrid to Panama City across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Panama City right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Madrid to Panama City

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