Cheap flights from Santo Domingo de los Tsáchilas

View AU$106 flight on Sun, 12 Apr 2026Opens in a new window

Popular airlines from Santo Domingo de los Tsáchilas

  • LATAM Airlines Group

  • Avianca

  • American Airlines

  • Delta

  • Copa

  • United

  • Air Canada

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 35% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Santo Domingo de los Tsáchilas

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Fri, 3 Apr - Sun, 5 Apr
UIO
Quito
GYE
Guayaquil
AU$207 Return, found 6 days ago
AU$207
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 3 Apr from Quito to Guayaquil, returning Sun, 5 Apr, priced at AU$207 found 6 days ago
LATAM Airlines Group
Tue, 21 Apr - Fri, 24 Apr
UIO
Quito
GYE
Guayaquil
AU$213 Return, found 14 hours ago
AU$213
Return
found 14 hours ago
Select LATAM Airlines Group flight, departing Tue, 21 Apr from Quito to Guayaquil, returning Fri, 24 Apr, priced at AU$213 found 14 hours ago
LATAM Airlines Group
Sat, 9 May - Sat, 16 May
UIO
Quito
GYE
Guayaquil
AU$214 Return, found 6 days ago
AU$214
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, 9 May from Quito to Guayaquil, returning Sat, 16 May, priced at AU$214 found 6 days ago
avianca
Sat, 9 May - Sat, 16 May
UIO
Quito
GYE
Guayaquil
AU$214 Return, found 6 days ago
AU$214
Return
found 6 days ago
Select avianca flight, departing Sat, 9 May from Quito to Guayaquil, returning Sat, 16 May, priced at AU$214 found 6 days ago
LATAM Airlines Group
Fri, 3 Apr - Sun, 5 Apr
UIO
Quito
GYE
Guayaquil
AU$214 Return, found 6 days ago
AU$214
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Fri, 3 Apr from Quito to Guayaquil, returning Sun, 5 Apr, priced at AU$214 found 6 days ago
avianca
Fri, 3 Apr - Sun, 5 Apr
UIO
Quito
GYE
Guayaquil
AU$217 Return, found 6 days ago
AU$217
Return
found 6 days ago
Select avianca flight, departing Fri, 3 Apr from Quito to Guayaquil, returning Sun, 5 Apr, priced at AU$217 found 6 days ago
LATAM Airlines Group
Tue, 21 Apr - Fri, 24 Apr
UIO
Quito
GYE
Guayaquil
AU$219 Return, found 14 hours ago
AU$219
Return
found 14 hours ago
Select LATAM Airlines Group flight, departing Tue, 21 Apr from Quito to Guayaquil, returning Fri, 24 Apr, priced at AU$219 found 14 hours ago
Copa
Fri, 10 Apr - Sun, 12 Apr
UIO
Quito
BOG
Bogotá
AU$444 Return, found 2 days ago
AU$444
Return
found 2 days ago
Select Copa flight, departing Fri, 10 Apr from Quito to Bogotá, returning Sun, 12 Apr, priced at AU$444 found 2 days ago
Delta
Tue, 7 Apr - Wed, 8 Apr
UIO
Quito
JFK
New York
AU$536 Return, found 3 days ago
AU$536
Return
found 3 days ago
Select Delta flight, departing Tue, 7 Apr from Quito to New York, returning Wed, 8 Apr, priced at AU$536 found 3 days ago
American Airlines
Tue, 18 Aug - Fri, 4 Sept
UIO
Quito
LGA
New York
AU$1,219 Return, found 4 days ago
AU$1,219
Return
found 4 days ago
Select American Airlines flight, departing Tue, 18 Aug from Quito to New York, returning Fri, 4 Sept, priced at AU$1,219 found 4 days ago

The Annual Holiday Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now
*Available to Expedia members.