Cheap flights from Madre de Dios Region

View AU$49 flight on Sun, 14 Sept 2025Opens in a new window

Popular airlines from Madre de Dios Region

  • LATAM Airlines Group

    LATAM Airlines Group

  • Sky Airlines

    Sky Airlines

  • Aerolineas Argentinas

    Aerolineas Argentinas

  • Iberia

    Iberia

  • Aeromexico

    Aeromexico

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Madre de Dios Region

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Thu, 18 Sept - Mon, 22 Sept
PEM
Puerto Maldonado
CUZ
Cusco
AU$180 Return, found 5 days ago
AU$180
Return
found 5 days ago
Select SKY AIRLINE flight, departing Thu, 18 Sept from Puerto Maldonado to Cusco, returning Mon, 22 Sept, priced at AU$180 found 5 days ago
LATAM Airlines Group
Thu, 18 Sept - Mon, 22 Sept
PEM
Puerto Maldonado
CUZ
Cusco
AU$198 Return, found 5 days ago
AU$198
Return
found 5 days ago
Select LATAM Airlines Group flight, departing Thu, 18 Sept from Puerto Maldonado to Cusco, returning Mon, 22 Sept, priced at AU$198 found 5 days ago
LATAM Airlines Group
Thu, 9 Oct - Sun, 12 Oct
PEM
Puerto Maldonado
LIM
Lima
AU$202 Return, found 5 days ago
AU$202
Return
found 5 days ago
Select LATAM Airlines Group flight, departing Thu, 9 Oct from Puerto Maldonado to Lima, returning Sun, 12 Oct, priced at AU$202 found 5 days ago
LATAM Airlines Group
Thu, 9 Oct - Sun, 12 Oct
PEM
Puerto Maldonado
LIM
Lima
AU$203 Return, found 5 days ago
AU$203
Return
found 5 days ago
Select LATAM Airlines Group flight, departing Thu, 9 Oct from Puerto Maldonado to Lima, returning Sun, 12 Oct, priced at AU$203 found 5 days ago
SKY AIRLINE
Thu, 18 Sept - Mon, 22 Sept
PEM
Puerto Maldonado
CUZ
Cusco
AU$209 Return, found 5 days ago
AU$209
Return
found 5 days ago
Select SKY AIRLINE flight, departing Thu, 18 Sept from Puerto Maldonado to Cusco, returning Mon, 22 Sept, priced at AU$209 found 5 days ago
LATAM Airlines Group
Thu, 6 Nov - Sun, 23 Nov
PEM
Puerto Maldonado
LIM
Lima
AU$210 Return, found 4 days ago
AU$210
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 6 Nov from Puerto Maldonado to Lima, returning Sun, 23 Nov, priced at AU$210 found 4 days ago
LATAM Airlines Group
Sat, 25 Oct - Mon, 27 Oct
PEM
Puerto Maldonado
LIM
Lima
AU$212 Return, found 1 day ago
AU$212
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Sat, 25 Oct from Puerto Maldonado to Lima, returning Mon, 27 Oct, priced at AU$212 found 1 day ago
LATAM Airlines Group
Sun, 16 Nov - Tue, 18 Nov
PEM
Puerto Maldonado
LIM
Lima
AU$214 Return, found 6 days ago
AU$214
Return
found 6 days ago
Select LATAM Airlines Group flight, departing Sun, 16 Nov from Puerto Maldonado to Lima, returning Tue, 18 Nov, priced at AU$214 found 6 days ago
SKY AIRLINE
Thu, 18 Sept - Mon, 22 Sept
PEM
Puerto Maldonado
CUZ
Cusco
AU$216 Return, found 5 days ago
AU$216
Return
found 5 days ago
Select SKY AIRLINE flight, departing Thu, 18 Sept from Puerto Maldonado to Cusco, returning Mon, 22 Sept, priced at AU$216 found 5 days ago
LATAM Airlines Group
Thu, 6 Nov - Sun, 23 Nov
PEM
Puerto Maldonado
LIM
Lima
AU$220 Return, found 4 days ago
AU$220
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Thu, 6 Nov from Puerto Maldonado to Lima, returning Sun, 23 Nov, priced at AU$220 found 4 days ago
*Available to Expedia members.