Cheap flights from Des Moines to South Suburbs

View AU$329 flight on Sat, 6 Sep. 2025Opens in a new window

Popular airlines from Des Moines to South Suburbs

  • Delta

    Delta

  • American Airlines

    American Airlines

  • United

    United

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Cheap Flights from Des Moines (DSM) to South Suburbs (CHI)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
ORD
Chicago
AU$290 Return, found 17 hours ago
AU$290
Return
found 17 hours ago
Select American Airlines flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$290 found 17 hours ago
American Airlines
Tue, 2 Sep. - Tue, 9 Sep.
DSM
Des Moines
ORD
Chicago
AU$293 Return, found 4 days ago
AU$293
Return
found 4 days ago
Select American Airlines flight, departing Tue, 2 Sep. from Des Moines to Chicago, returning Tue, 9 Sep., priced at AU$293 found 4 days ago
Delta
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MDW
Chicago
AU$320 Return, found 17 hours ago
AU$320
Return
found 17 hours ago
Select Delta flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$320 found 17 hours ago
Delta
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
ORD
Chicago
AU$320 Return, found 17 hours ago
AU$320
Return
found 17 hours ago
Select Delta flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$320 found 17 hours ago
Delta
Tue, 2 Sep. - Tue, 9 Sep.
DSM
Des Moines
ORD
Chicago
AU$323 Return, found 4 days ago
AU$323
Return
found 4 days ago
Select Delta flight, departing Tue, 2 Sep. from Des Moines to Chicago, returning Tue, 9 Sep., priced at AU$323 found 4 days ago
United
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
ORD
Chicago
AU$428 Return, found 17 hours ago
AU$428
Return
found 17 hours ago
Select United flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$428 found 17 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Chicago (ORD)

September is typically the cheapest month to fly

From AU$212 - AU$451 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.