Cheap flights from Panama

View AU$226 flight on Mon, 17 Nov 2025Opens in a new window

Popular airlines from Panama

  • Avianca

    Avianca

  • United

    United

  • Copa

    Copa

  • American Airlines

    American Airlines

  • Delta

    Delta

  • Aeromexico

    Aeromexico

  • KLM

    KLM

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Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, 6 Nov - Mon, 10 Nov
PTY
Panama City
MDE
Medellin
AU$426 Return, found 9 hours ago
AU$426
Return
found 9 hours ago
Select Copa flight, departing Thu, 6 Nov from Panama City to Medellin, returning Mon, 10 Nov, priced at AU$426 found 9 hours ago
Copa
Thu, 6 Nov - Mon, 10 Nov
PTY
Panama City
MDE
Medellin
AU$442 Return, found 9 hours ago
AU$442
Return
found 9 hours ago
Select Copa flight, departing Thu, 6 Nov from Panama City to Medellin, returning Mon, 10 Nov, priced at AU$442 found 9 hours ago
Copa
Sun, 9 Nov - Wed, 12 Nov
PTY
Panama City
MDE
Medellin
AU$474 Return, found 4 days ago
AU$474
Return
found 4 days ago
Select Copa flight, departing Sun, 9 Nov from Panama City to Medellin, returning Wed, 12 Nov, priced at AU$474 found 4 days ago
Copa
Thu, 6 Nov - Mon, 10 Nov
PTY
Panama City
MDE
Medellin
AU$500 Return, found 9 hours ago
AU$500
Return
found 9 hours ago
Select Copa flight, departing Thu, 6 Nov from Panama City to Medellin, returning Mon, 10 Nov, priced at AU$500 found 9 hours ago
Copa
Sun, 9 Nov - Wed, 12 Nov
PTY
Panama City
MDE
Medellin
AU$507 Return, found 4 days ago
AU$507
Return
found 4 days ago
Select Copa flight, departing Sun, 9 Nov from Panama City to Medellin, returning Wed, 12 Nov, priced at AU$507 found 4 days ago
Copa
Thu, 6 Nov - Sun, 9 Nov
PTY
Panama City
MIA
Miami
AU$509 Return, found 4 days ago
AU$509
Return
found 4 days ago
Select Copa flight, departing Thu, 6 Nov from Panama City to Miami, returning Sun, 9 Nov, priced at AU$509 found 4 days ago
avianca
Thu, 6 Nov - Mon, 10 Nov
PTY
Panama City
MDE
Medellin
AU$553 Return, found 9 hours ago
AU$553
Return
found 9 hours ago
Select avianca flight, departing Thu, 6 Nov from Panama City to Medellin, returning Mon, 10 Nov, priced at AU$553 found 9 hours ago
Aeromexico
Mon, 24 Nov - Sun, 7 Dec
PTY
Panama City
CUN
Cancun
AU$575 Return, found 5 days ago
AU$575
Return
found 5 days ago
Select Aeromexico flight, departing Mon, 24 Nov from Panama City to Cancun, returning Sun, 7 Dec, priced at AU$575 found 5 days ago
American Airlines
Thu, 6 Nov - Sat, 8 Nov
PTY
Panama City
MIA
Miami
AU$621 Return, found 1 day ago
AU$621
Return
found 1 day ago
Select American Airlines flight, departing Thu, 6 Nov from Panama City to Miami, returning Sat, 8 Nov, priced at AU$621 found 1 day ago
Delta
Thu, 30 Oct - Mon, 3 Nov
PTY
Panama City
MIA
Miami
AU$937 Return, found 1 day ago
AU$937
Return
found 1 day ago
Select Delta flight, departing Thu, 30 Oct from Panama City to Miami, returning Mon, 3 Nov, priced at AU$937 found 1 day ago
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