Uptown Greenville Holidays
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Our guide on where to stay in Uptown Greenville
Find the best Uptown Greenville areas and neighborhoods for the activities you enjoy most. Learn more about Uptown Greenville
Medical District
1 out of top 10 points of interest in this area
If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and North Pines.
Our pick of the best Uptown Greenville Hotel Deals
Hilton Garden INN Greenville University
423 EVANS ST Greenville NC
Fully refundableReserve now, pay when you stay
The price is AU$202 per night from 21 Dec to 22 Dec
AU$202
21 Dec - 22 Dec
includes taxes & fees
9.4/10 Exceptional! (91 reviews)
Great location. Rooftop bar and restaurant was nice and convenient.
Reviewed on 18 Nov 2025
Staybridge Suites Greenville Medical Center by IHG
930 Crosswind Street Greenville NC
Fully refundable
The price is AU$170 per night from 21 Dec to 22 Dec
AU$170
21 Dec - 22 Dec
includes taxes & fees
9.2/10 Wonderful! (230 reviews)
Very clean and comfortable
Reviewed on 8 Dec 2025
Microtel Inn & Suites by Wyndham Greenville/University Medic
450 Moye Blvd Greenville NC
Fully refundableReserve now, pay when you stay
The price is AU$107 per night from 21 Dec to 22 Dec
AU$107
21 Dec - 22 Dec
includes taxes & fees
7/10 Good! (1,001 reviews)
Small bed but good service
Reviewed on 12 Dec 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.