Lodging Image

Uptown Greenville Hotels, Greenville

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
3 July - 5 July
Next weekend
10 July - 12 July

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Property class

Our top choices for Uptown Greenville hotels

Exterior

Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (144 reviews)
"Excellent location!"
United States
Cammie
The price is AU$247
includes taxes & fees
19 July - 20 July
Hilton Garden INN Greenville University
Apartment 1 - Pet Friendly | Private kitchen

Little Inn on Main

Little Inn on Main
3.0 star property
29.7 km from Uptown Greenville
9.8 out of 10, Exceptional, (97 reviews)
"Clean rooms pet friendly and relaxing dining areas around this place "
United States
Olga
The price is AU$223
includes taxes & fees
5 July - 6 July
Little Inn on Main
Terrace/patio

Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
2.4 km from Uptown Greenville
9.4 out of 10, Exceptional, (372 reviews)
"It would have been nice if there was a pool. Overall very nice hotel. Would stay again if in Greenville."
United States
Bill
The price is AU$158
includes taxes & fees
26 July - 27 July
Homewood Suites By Hilton Greenville, NC
Superior Room, 1 King Bed, Non Smoking, Jetted Tub

Red Roof Inn Washington, NC

Red Roof Inn Washington, NC
2.5 star property
29.2 km from Uptown Greenville
6.6 out of 10, (114 reviews)
"This property does welcome dogs. Free for one and 15 clams for to. 80 pound limit per dog. There is limitted and tight truck parking. Property was clean and staff more than accommodating. Would definitely stay again!"
United States
David
The price is AU$108
includes taxes & fees
4 July - 5 July
Red Roof Inn Washington, NC
Restaurant

Hampton Inn Washington

Hampton Inn Washington
2.5 star property
28 km from Uptown Greenville
8.2 out of 10, Very good, (712 reviews)
"Everything was great. Bedt breakfast in a hotel that I have ever had."
United States
Daniel
The price is AU$176
includes taxes & fees
12 July - 13 July
Hampton Inn Washington
Exterior

Fairfield Inn and Suites by Marriott Washington

Fairfield Inn and Suites by Marriott Washington
3.0 star property
27.1 km from Uptown Greenville
9.4 out of 10, Exceptional, (669 reviews)
"Great place to stay!"
United States
Diane
The price is AU$193
includes taxes & fees
20 July - 21 July
Fairfield Inn and Suites by Marriott Washington
Exterior

Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
2.3 km from Uptown Greenville
9.2 out of 10, Wonderful, (332 reviews)
"Great accommodations"
United States
lisa
The price is AU$199
includes taxes & fees
12 July - 13 July
Staybridge Suites Greenville Medical Center by IHG
Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (with Sofabed)

Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
3.9 km from Uptown Greenville
9.0 out of 10, Wonderful, (1,013 reviews)
"Incredibly clean, quiet, comfortable and accommodating."
United States
Lauren
The price is AU$176
includes taxes & fees
12 July - 13 July
Best Western Plus Suites-Greenville
Free WiFi, bed sheets

Motel 6 Greenville, NC – ECU-Medical Center

Motel 6 Greenville, NC – ECU-Medical Center
2.0 star property
2.2 km from Uptown Greenville
6.4 out of 10, (113 reviews)
"It stunk like hell in the room"
United States
Stefan W
The price is AU$119
includes taxes & fees
5 July - 6 July
Motel 6 Greenville, NC – ECU-Medical Center
Free daily buffet breakfast

Quality Inn Washington NC

Quality Inn Washington NC
2.5 star property
28.5 km from Uptown Greenville
7.8 out of 10, Good, (397 reviews)
"over all good stay, not the fanciest hotel but had everything we needed for a quick weekend out of town!"
United States
Carrah
The price is AU$154
includes taxes & fees
2 July - 3 July
Quality Inn Washington NC
Lobby

Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
4.9 km from Uptown Greenville
8.8 out of 10, Excellent, (502 reviews)
"Very comfortable beds and breakfast was outstanding. I will definitely stay here again."
United States
Kenneth
The price is AU$187
includes taxes & fees
17 July - 18 July
Comfort Inn & Suites Greenville Near East Carolina University
Suite, 1 Bedroom, Non Smoking, Jetted Tub

Country Inn & Suites by Radisson, Greenville, NC

Country Inn & Suites by Radisson, Greenville, NC
3.0 star property
6.7 km from Uptown Greenville
7.6 out of 10, Good, (887 reviews)
"clean rooms, friendly staff, everything was good."
United States
Zoya
The price is AU$161
includes taxes & fees
27 July - 28 July
Country Inn & Suites by Radisson, Greenville, NC
Lobby

Economy Inn of Greenville, NC

Economy Inn of Greenville, NC
2.5 star property
2.1 km from Uptown Greenville
4.6 out of 10, (108 reviews)
"The room was very well kept and it was a nice quick quiet stay"
United States
Chris
The price is AU$83
includes taxes & fees
27 July - 28 July
Economy Inn of Greenville, NC
Exterior

Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
2.0 star property
2.5 km from Uptown Greenville
7.0 out of 10, Good, (1,000 reviews)
"Was very nice."
United States
Wayne
The price is AU$106
includes taxes & fees
5 July - 6 July
Microtel Inn & Suites by Wyndham Greenville/University Medic
Exterior

Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 4.3 km from Uptown Greenville
8.8 out of 10, Excellent, (1,001 reviews)
"Great hotel"
United States
Theresa
The price is AU$150
includes taxes & fees
20 July - 21 July
Holiday Inn Greenville by IHG
Exterior

Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
2.3 km from Uptown Greenville
8.4 out of 10, Very good, (1,000 reviews)
"Very clean and comfortable stay!"
United States
Kyrie
The price is AU$193
includes taxes & fees
12 July - 13 July
Holiday Inn Express Greenville by IHG
Indoor pool

Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.8 out of 10, Excellent, (495 reviews)
"My family were greeted by a gentleman named "Mo" when we checked in and he was very welcoming, professional and polite to us. The housekeeping crew did a wonderful job during our stay. We definitely plan on coming back to this hotel when we plan to visit North Carolina again"
United States
Lonnelle
The price is AU$179
includes taxes & fees
19 July - 20 July
Fairfield Inn & Suites by Marriott Greenville
Terrace/patio

Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 4.3 km from Uptown Greenville
9.0 out of 10, Wonderful, (625 reviews)
"Very nice place to stay if you are in Greenville."
United States
Christopher
The price is AU$200
includes taxes & fees
19 July - 20 July
Hampton Inn Greenville
Desk, iron/ironing board, free cots/infant beds, free WiFi

Days Inn by Wyndham Washington

Days Inn by Wyndham Washington
2.0 star property
29.2 km from Uptown Greenville
4.6 out of 10, (144 reviews)
"The hotel is in very poor condition. There is no closet in the room. It definitely shouldn't be on your website with a 4.6 rating. We didn't stay there. As soon as we saw the condition of the hotel, we cancelled."
United States
Debbie
The price is AU$109
includes taxes & fees
5 July - 6 July
Days Inn by Wyndham Washington
Terrace/patio

Hilton Greenville

Hilton Greenville
4.0 star property
Convention District, 4.5 km from Uptown Greenville
8.8 out of 10, Excellent, (557 reviews)
"We had a great experience in this Hotel! Thank you!"
United States
Maria
The price is AU$246
includes taxes & fees
12 July - 13 July
Hilton Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in Uptown Greenville

Find the best Uptown Greenville areas for the activities you enjoy most.

University District

While University District isn't home to many top sights, Greenville Museum of Art and Dowdy–Ficklen Stadium are some notable places to visit nearby.

Convention District

When in Convention District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area.

Medical District

If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and North Pines.

Westhaven

Westhaven might not have many top sights, but 11 Galleria and Arlington Crossing are two attractions nearby that you can check out.

Greenville Heights

If you're looking for some top things to see and do in Greenville Heights and surrounding area, you can visit North Pines and Greenville Museum of Art.

Top Uptown Greenville Hotel Reviews

Recent Reviews in Uptown Greenville

Hampton Inn Greenville

Hampton Inn Greenville

10/10 Excellent
"This was a very good hotel. Stayed one night. Only negative in an area where traffic is not the best."
Rosalind 1-night trip
Posted 9 hours ago
Hampton Inn Greenville

Frequently asked questions

What are the best family hotels in Uptown Greenville?
For an excellent family stay in Uptown Greenville, consider the Hilton Garden INN Greenville University.

The 3-star Hilton Garden Inn Greenville University, with an outstanding 9.4 rating, is a superb choice for families. This hotel offers complimentary cribs and connecting rooms, which are very convenient for larger families. It is located in a historical and shopping district, making it easy to explore. Guests will appreciate the on-site gift shops or newsstand and a grocery or convenience store for any family needs. The hotel is also very close to Town Common, just 0.5 km away, providing a pleasant area for families to relax.
What are the top pet-friendly hotels in Uptown Greenville?
For a highly-rated pet-friendly hotel in Uptown Greenville, consider the Hilton Garden INN Greenville University.

This 3-star hotel, with an impressive 9.4 rating, warmly welcomes pets, making it an excellent choice for travellers with animal companions. It is conveniently located in a historical district, close to a shopping district, and has a museum nearby. Guests will find a gift shop or newsstand on-site, as well as a grocery and convenience store for any necessities. The hotel is also just 0.5 km from Town Common, offering easy access to a pleasant green space.
What are the best budget hotels in Uptown Greenville?
For a budget-friendly and highly-rated hotel in Uptown Greenville, consider the Hilton Garden INN Greenville University.

The 3-star Hilton Garden Inn Greenville University, with an impressive 9.4 rating, offers a comfortable stay with excellent amenities. It is conveniently located in a historical and shopping district, with a museum nearby. Guests can enjoy complimentary WiFi and the convenience of a gift shop or newsstand, as well as a grocery or convenience store on-site. The hotel is also well-situated for exploring local attractions, being just 0.5 km from Town Common.
When is the best time to go to Uptown Greenville?
The best time to go to Uptown Greenville is during the spring (April to May) and autumn (September to October) months.

During these periods, the weather is pleasantly mild with comfortable temperatures, making it ideal for exploring the city's outdoor attractions and enjoying events. You'll find fewer humid days compared to summer, and the natural beauty of North Carolina is on full display, especially the autumn foliage.

For those interested in university activities, visiting in late spring or early autumn allows you to experience the buzz of East Carolina University without the peak summer heat.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Uptown Greenville hotel for you.
How can I save on a hotel booking in Uptown Greenville with Expedia?
One Key™ – Expedia's free travel rewards program – gives you instant access to perks and Member Prices on Uptown Greenville hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Uptown Greenville?
Hotel prices in Uptown Greenville often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.