
Upstate South Carolina Holidays
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Your Upstate South Carolina Holiday
With a Upstate South Carolina holiday package, you can forget about the stress of planning and simply focus on experiencing what this thrilling destination has on offer. With so much to do and see on a trip to Upstate South Carolina, it can be hard to know where to begin. Kick off your travels in Greenville at Falls Park on the Reedy and Bon Secours Wellness Arena — two popular attractions here. Another top city worthy of a spot on your itinerary is Spartanburg. Don't miss WestGate Mall and Tyger River Park. Expedia is your one-stop shop for planning your Upstate South Carolina holiday. From hotels and flights, to car rentals and more, we're here to help you create a travel experience like no other.
Our guide on where to stay in Upstate South Carolina

Greenville Downtown
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Upstate South Carolina Holiday
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charleston Intl. Airport (CHS) |
Top Sights | Falls Park on the Reedy, Lake Keowee and Heritage Park |
Our pick of the best Upstate South Carolina Hotel Deals

Best Western Plus Greenville I-385 Inn & Suites
"Room was nice and tidy. Breakfast was good. Parking was convenient. Overall a very good experience."
Reviewed on 8 Nov 2026

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Days Inn by Wyndham Greenville
"Always a great stay"
Reviewed on 6 Nov 2026
Stay near popular Upstate South Carolina attractions
What to do in Upstate South Carolina

Greenville Ghost Tour with Paranormal Investigation

Guided E-Bike Tour in Greenville South Carolina with Brunch
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