Photo by Ryan Watts

Search Upstate South Carolina hotels
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Check prices for these dates
Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
10.0 out of 10, Exceptional, (1 review)
The price is AU$85
includes taxes & fees
17 May - 18 May

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is AU$97
includes taxes & fees
26 May - 27 May

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is AU$363
includes taxes & fees
19 May - 20 May

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (702 reviews)
The price is AU$139
includes taxes & fees
14 June - 15 June

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (229 reviews)
The price is AU$199
includes taxes & fees
24 May - 25 May

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (713 reviews)
The price is AU$128
includes taxes & fees
14 June - 15 June

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is AU$175
includes taxes & fees
7 June - 8 June

Clemson Memorabilia House
Clemson Memorabilia HouseClemson
9.6 out of 10, Exceptional, (10 reviews)
The price is AU$332
includes taxes & fees
19 May - 20 May

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,003 reviews)
The price is AU$189
includes taxes & fees
17 May - 18 May

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (789 reviews)
The price is AU$159
includes taxes & fees
24 May - 25 May

Baymont by Wyndham Greenwood
Baymont by Wyndham GreenwoodGreenwood
7.6 out of 10, Good, (828 reviews)
The price is AU$111
includes taxes & fees
24 May - 25 May

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (615 reviews)
The price is AU$171
includes taxes & fees
24 May - 25 May

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,202 reviews)
The price is AU$169
includes taxes & fees
7 June - 8 June

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,010 reviews)
The price is AU$231
includes taxes & fees
17 May - 18 May

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,002 reviews)
The price is AU$170
includes taxes & fees
14 June - 15 June

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (710 reviews)
The price is AU$190
includes taxes & fees
7 June - 8 June

Best Western Seneca-Clemson
Best Western Seneca-ClemsonSeneca
8.4 out of 10, Very good, (659 reviews)
The price is AU$150
includes taxes & fees
19 May - 20 May

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (599 reviews)
The price is AU$220
includes taxes & fees
19 May - 20 May

Aloft by Marriott Greenville Downtown
Aloft by Marriott Greenville DowntownGreenville Downtown
9.2 out of 10, Wonderful, (1,001 reviews)
The price is AU$205
includes taxes & fees
24 May - 25 May

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (457 reviews)
The price is AU$212
includes taxes & fees
17 May - 18 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (73 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
More cheap accommodation in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is AU$92 per night from 14 June to 15 June
AU$92
14 June - 15 June
includes taxes & fees
6/10 (601 reviews)
Explore a world of travel with Expedia
- Pet Friendly Hotels in Boiling Springs
- Boiling Springs Hotels
- Cabin Rentals in Clinton
- Holiday Homes in Clinton
- Spartanburg County Hotels
- Drayton Hotels
- Caravan Parks in Duncan
- Cottages in Duncan
- Duncan Hotels
- Enoree Hotels
- Fingerville Hotels
- Five Forks Hotels
- Fountain Inn Hotels
- Gray Court Hotels
- Hotels near Greenville-Spartanburg Intl.
- Greer Hotels
- Hotels near Heritage Park
- Inman Hotels
- Laurens Hotels
- Lyman Hotels
- Mauldin Hotels
- Moore Hotels
- Holiday Homes in Pauline
- Pauline Hotels
- Caravan Parks in Roebuck
- Roebuck Hotels
- Lodges in Roebuck
- Hotels near Shipwreck Cove
- Caravan Parks in Southern Shops
- Cheap Hotels in Southern Shops
- All Inclusive Hotels in Spartanburg
- Spartanburg Hotels
- Hotels near Spartanburg Regional Hospital
- Startex Hotels
- Beach Hotels in Taylors
- Family Hotels in Taylors
- Taylors Hotels
- Hotels near Tyger River Park
- Una Hotels
- Upstate South Carolina Hotels
- Wellford Hotels
- Hotels near Wofford College
- Cheap Hotels in Woodruff
- Luxury Hotels in Woodruff
- Woodruff Hotels
- Flights to Buffalo
- Flights to Fairforest
- Flights to Five Forks
- Flights to Greenville-Spartanburg Intl.
- Flights to Laurens
- Flights to Roebuck
- Flights to Simpsonville
- Flights to Southern Shops
- Flights to Spartanburg
- Flights to Una
- Flights from Donaldson Center
- Flights from Greenville Downtown
- Flights from Greenville-Spartanburg Intl.
- Flights from Denver to Upstate South Carolina
- Flights from Philadelphia to Upstate South Carolina
- Flights from Startex
- Flights from Gray Court
- Flights from Wellford
- Flights from Boiling Springs
- Flights from Taylors
- Flights from Duncan
- Flights from Adelaide (ADL) to Greenville (GSP)
- Flights from Anderson (AND) to Greenville (GMU)
- Flights from Atlanta (ATL) to Greenville (GSP)
- Flights from Mobile (BFM) to Greenville (GMU)
- Flights from Brisbane (BNE) to Greenville (GSP)
- Flights from Charlotte (CLT) to Greenville (GSP)
- Flights from Coeur d'Alene (COE) to Greenville (GSP)
- Flights from Dallas (DFW) to Greenville (GSP)
- Flights from Dillon (DLL) to Greenville (GDC)
- Flights from Delta (DTA) to Greenville (GSP)
- Flights from Ankara (ESB) to Greenville (GSP)
- Flights from Gulfport (GPT) to Greenville (GDC)
- Flights from Greenwood (GRD) to Greenville (GMU)
- Flights from Honolulu (HNL) to Greenville (GSP)
- Flights from Houston (IAH) to Greenville (GSP)
- Flights from Indianapolis (IND) to Greenville (GDC)
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from New York (LGA) to Greenville (GSP)
- Flights from Orlando (MCO) to Greenville (GSP)
- Flights from Melbourne (MEL) to Greenville (GSP)
- Flights from Miami (MIA) to Greenville (GDC)
- Flights from Miami (MIA) to Greenville (GMU)
- Flights from Melbourne (MLB) to Greenville (GSP)
- Flights from Chicago (ORD) to Greenville (GMU)
- Flights from Perth (PER) to Greenville (GSP)
- Flights from Rota (ROP) to Greenville (GSP)
- Flights from San Francisco (SFO) to Greenville (GSP)
- Flights from Sydney (SYD) to Greenville (GSP)
- Flights from Varginha (VAG) to Greenville (GSP)






























































































































