Photo by Ryan Watts
Search Upstate South Carolina hotels
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels
Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (710)
"Comfortable bed, nice fridge, tv, microwave."
Lindsay
Travelling for leisure
The price is AU$173
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express & Suites Greenwood Mall by IHG
Holiday Inn Express & Suites Greenwood Mall by IHGGreenwood
9.0 out of 10, Wonderful, (486)
"Our room was clean and very nice;"
Louie
Travelling with family
The price is AU$250
includes taxes & fees
2 Jan - 3 Jan 2026
9.4 out of 10, Exceptional, (686)
"Always a friendly welcome from professional and helpful staff, clean rooms and a good choice for breakfast in the morning."
John
Travelling with partner
The price is AU$230
includes taxes & fees
7 Jan - 8 Jan 2026
8.0 out of 10, Very good, (1002)
"Rooms are clean and well maintained"
Greg
Travelling with family
9.4 out of 10, Exceptional, (439)
"Rooms are quiet and clean"
Ashley
The price is AU$197
includes taxes & fees
1 Jan - 2 Jan 2026
9.6 out of 10, Exceptional, (416)
"Beautiful property, great staff, very nice rooms."
Heather
Travelling for leisure
The price is AU$226
includes taxes & fees
1 Jan - 2 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cottage
9.8 out of 10, Exceptional, (9)
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Stay near popular Southeastern United States attractions
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Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.
Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Recent Reviews in Upstate South Carolina
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
10/10 Excellent
More cheap accommodation in Upstate South Carolina
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is AU$104 per night from 4 Jan to 5 Jan
AU$104
4 Jan - 5 Jan 2026
includes taxes & fees
7.8/10 Good! (1,001 reviews)
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