Default HTG hotel image

Search St. Charles hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Filter by

Property class

Guest rating

Our top choices for St. Charles hotels

1. Quality Inn Harlan

Quality Inn Harlan
Harlan
United States
Beau
AU$141
includes taxes & fees
14 Nov - 15 Nov
Quality Inn Harlan

2. Travel Inn - Duffield

Travel Inn - Duffield
Duffield
United States
Joan
AU$92
includes taxes & fees
21 Nov - 22 Nov
Travel Inn - Duffield

3. Quality Inn & Suites Big Stone Gap

Quality Inn & Suites Big Stone Gap
Big Stone Gap
Canada
Donald
AU$153
includes taxes & fees
29 Oct - 30 Oct
Quality Inn & Suites Big Stone Gap
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top St. Charles Hotel Reviews

Recent Reviews in St. Charles

Bed and Biscuit Inn 
Pet friendly !
Near Kingdom come park & Pine mtn.

Bed and Biscuit Inn Pet friendly ! Near Kingdom come park & Pine mtn.

10/10 Excellent
"Best stay we have had in the area. Wonderful place. Will stay here again!!!"
Darren 2-night trip
Posted 2 days ago
Bed and Biscuit Inn Pet friendly ! Near Kingdom come park & Pine mtn.
Deer Meadow-Devil`s Bathtub/Natural Tunnel

Deer Meadow-Devil`s Bathtub/Natural Tunnel

10/10 Excellent
"The cabin was perfect. It was clean and homey. We enjoyed it very much and hope to be back. The host brought us over some wood. I really enjoyed the tree out front with all the beautiful leaves on the ground. Hope to be back!"
Carolyn K. 3-night trip
Posted 2 days ago
Deer Meadow-Devil`s Bathtub/Natural Tunnel
Quality Inn Harlan

Quality Inn Harlan

10/10 Excellent
"Great place"
Cristopher 1-night trip
Posted 4 days ago
Quality Inn Harlan
Family farm guest house 10 minutes from Big Stone

Family farm guest house 10 minutes from Big Stone

10/10 Excellent
"Wonderful accommodation! Clean, great lighting, nicely decorated, well-stocked, modern kitchen."
John T. 3-night trip
Posted 9 days ago
Family farm guest house 10 minutes from Big Stone
Cozy log cabin near Pennington Gap and Jonesville, VA known as "The Duck Pond"

Cozy log cabin near Pennington Gap and Jonesville, VA known as "The Duck Pond"

8/10 Good
"Very nice and relaxing. Only draw back was no wifi in case of emergency there is no way to call anyone. But the ducks and geese and quiet does help you unplug. Thank you"
Dee S. 4-night trip
Posted 13 days ago
Cozy log cabin near Pennington Gap and Jonesville, VA known as "The Duck Pond"
Scenic Farm Loft in Amish Country w/ Epic Views

Scenic Farm Loft in Amish Country w/ Epic Views

10/10 Excellent
"Charming, clean, quiet loft. Exactly as described and pictured. Comfortable bed, minimalist kitchen, peaceful porch. Highly recommend to restore your soul in the beauty of the land."
Linda G. 2-night trip
Posted 2 weeks ago
Scenic Farm Loft in Amish Country w/ Epic Views
Peaceful tranquility from a river view cabin

Peaceful tranquility from a river view cabin

10/10 Excellent
"Ken was an amazing host! He was there when we needed some assistance checking in and again later when we had some questions. The cabin is beautiful and perfect for what we needed while here visiting family close by! We definitely plan to make this our place to stay when we come back for visits! Thank you for an awesome vacay!"
Anne 4-night trip
Posted 1 month ago
Peaceful tranquility from a river view cabin
The Appalachian Oasis

The Appalachian Oasis

10/10 Excellent
"Absolutely amazing!!"
Kellie S. 5-night trip
Posted 2 months ago
The Appalachian Oasis
Handicapped Friendly House in the peaceful country side

Handicapped Friendly House in the peaceful country side

10/10 Excellent
"Highly recommended. I plan to visit again. The sooner the better! There is just nothing to not love. And Nell is great with being readily available and her eye for real country charm."
Kelly M. 3-night trip
Posted 2 months ago
Handicapped Friendly House in the peaceful country side

More cheap accommodation in St. Charles

Travel Inn - Duffield

Travel Inn - Duffield

382 Duff Patt Hwy Duffield VA
AU$92
21 Nov - 22 Nov
includes taxes & fees
Travel Inn - Duffield
Quality Inn Harlan

Quality Inn Harlan

2608 South Highway 421 Harlan KY
AU$141
14 Nov - 15 Nov
includes taxes & fees
8.6/10 Excellent! (395 reviews)
Quality Inn Harlan
Quality Inn & Suites Big Stone Gap

Quality Inn & Suites Big Stone Gap

4609 Aerial Way Big Stone Gap VA
AU$154
1 Nov - 2 Nov
includes taxes & fees
9.4/10 Exceptional! (534 reviews)
Quality Inn & Suites Big Stone Gap
Harlan County Campground & Cabin Rentals

Harlan County Campground & Cabin Rentals

8331 Hwy 119 N Putney KY
Get ratesHarlan County Campground & Cabin Rentals

Frequently asked questions

What is the best area to stay in St Charles?
The best area to stay in St Charles is the historic Main Street district, which runs parallel to the Missouri River.This area is the heart of St Charles, known for its beautifully preserved brick buildings, gas lamps, and cobblestone streets. Main Street itself is pedestrian-friendly, lined with independent shops, art galleries, and a variety of restaurants. It's a very walkable area, stretching from the First State Capitol Building on the north end to the Lewis & Clark Boat House and Museum towards the south.Couples often find this area great for a relaxing getaway. You can enjoy strolls along the riverfront, explore the numerous unique boutiques, and dine at charming restaurants, many of which offer outdoor seating. The evening entertainment, including live music venues, is also easily accessible.For those interested in history and exploring on foot, staying close to Main Street is ideal. You're within easy reach of historic sites like the Boone's Lick Road and the starting point of the Lewis and Clark expedition.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in St. Charles.
How can I save on a hotel booking in St. Charles with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on St. Charles hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in St. Charles?
Prices for hotels in St. Charles often vary, but you can find a great deal from AU$92 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia