Spa Hotels & Resorts in Southwest Illinois from AU$186

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Southwest Illinois Spa Hotels

This weekend
Next weekend

Best Southwest Illinois Spa Hotels

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1006)
"Great place to stay. "
The price is AU$186
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1002)
"Great hotel, loved the room"
The price is AU$768
includes taxes & fees
19 Aug - 20 Aug
Four Seasons Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1285)
"Great place to stay. "
The price is AU$283
includes taxes & fees
31 Aug - 1 Sept
21C Museum Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (540)
"Wish they still had a pool"
The price is AU$1,042
includes taxes & fees
10 Aug - 11 Aug
The Ritz-Carlton, St. Louis

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1009)
"NICE AREA TO STAY"
The price is AU$331
includes taxes & fees
10 Aug - 11 Aug
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southwest Illinois Hotel Reviews