A calm lake surrounded by trees and vegetation.

Business Hotels & Resorts in Southwest Illinois from AU$100

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Check availability on Southwest Illinois Business Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Southwest Illinois business-friendly hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A compact kitchenette with a refrigerator and an ice dispenser.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.
A hotel room with two beds, a desk, and a window with a view.

1. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Steven
AU$188
includes taxes & fees
18 Oct - 19 Oct
Best Western U. S. Inn
A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.
A reception area with a counter, framed certificates, a clock, and a checkered floor.
A Super 8 motel with a covered entrance, outdoor seating, and a vending machine.
A bathroom with a granite countertop sink, a mirror, a towel rack, and a telephone.

2. Super 8 by Wyndham Okawville

Super 8 by Wyndham Okawville
Okawville
United States
Peter
AU$100
includes taxes & fees
1 Nov - 2 Nov
Super 8 by Wyndham Okawville
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.
A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.
A spacious lobby with a large seating area, a reception desk, and a television.
A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.

3. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
Centralia
United States
Jeremy
AU$224
includes taxes & fees
20 Oct - 21 Oct
Best Western Plus Centralia Hotel & Suites
A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.
A patio area with outdoor seating, including chairs and tables, and a covered area with umbrellas.
A compact hotel room with a kitchenette, a blue sofa, a small wooden table, and a wooden floor.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

4. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
Sparta
United States
NADINE
AU$160
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Hotel & Suites Sparta by IHG
A bar area with a long counter, multiple chairs, and hanging light fixtures.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

5. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Richard
AU$180
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Mt. Vernon
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A hallway with vending machines and a carpeted floor.
A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.

6. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
Michelle
AU$137
includes taxes & fees
19 Oct - 20 Oct
SureStay Hotel by Best Western Whittington Rend Lake
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.
A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.
A hotel room with a sofa, two lamps, a television, and a desk.
A hotel room with a wooden dining table, four brown chairs, a beige sofa, a small wooden coffee table, a lamp, a framed picture on the wall, and a kitchenette with a microwave.

7. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
Highland
United States
Jeffrey
AU$143
includes taxes & fees
8 Nov - 9 Nov
Seasons Inn & Suites Highland
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with two beds, a television, a desk, and a window with curtains.
A Country Inn Motel sign, a parking lot, and a building with an American flag.

8. Red Bud Country Inn

Red Bud Country Inn
Red Bud
United States
James
AU$140
includes taxes & fees
18 Oct - 19 Oct
Red Bud Country Inn
A hotel room with a bed, a television, a desk, and a chair.
A reception area with a reception desk, a computer, a sewing machine, and an exit sign.
A multi-story hotel with a covered entrance, a Super 8 logo, and a brick facade.
A breakfast area with a counter, microwave, coffee machine, and seating.

9. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
Greenville
United States
Sharon
AU$101
includes taxes & fees
21 Oct - 22 Oct
Super 8 by Wyndham Greenville
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.
A casino interior with slot machines, a large chandelier, and a carpeted floor.

10. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Ron
AU$184
includes taxes & fees
19 Oct - 20 Oct
Walker's Bluff Casino Resort
View all properties

Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Huge room and very clean. Amazing hotel. Well worth the money. Kickbacks was a nice snack for us, but didn't care for the chili. Breakfast was very good. It was busy but the food area is large so it didn't seem over packed. We would stay here again!"
Kristin 1-night trip
Posted 17 hours ago
Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"It was disappointing to not have any protein options for breakfast, and only apples as fruit."
Clara 4-night trip
Posted 1 day ago
Quality Inn O'Fallon - St. Louis - Shiloh
Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis

10/10 Excellent
"Our hotel stay was absolutely amazing! It was peaceful, relaxing, and honestly one of the best stays we’ve ever had. Everything about the experience made it easy to unwind, enjoy ourselves, and truly relax. Sometimes you just need a little getaway to recharge, and this was exactly that. We left feeling refreshed and happy, and we would absolutely love to stay here again. Highly recommend to anyone looking for a wonderful, relaxing experience! ❤️"
Scott Thompson 3-night trip
Posted 2 days ago
Radisson Hotel Fairview Heights - St. Louis
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Nice affordable with comfortable beds and good food."
Heather 1-night trip
Posted 2 days ago
Drury Inn & Suites Marion
Best Western Marion Hotel

Best Western Marion Hotel

8/10 Good
"The room was clean and comfortable. Staff was friendly and check in went smoothly. Breakfast was good and coffee is always available. Hotel is being remodeled. Hallways are a mess now. Stay was excellent overall."
David 1-night trip
Posted 3 days ago
Best Western Marion Hotel

Frequently asked questions

How much do business-friendly hotels in Southwest Illinois cost?
Rates for business hotels in Southwest Illinois range between AU$100 and AU$188 per night. No matter your budget, Expedia will help you locate the best space to get the job done. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southwest Illinois?
Southwest Illinois has 105 business-friendly hotels to choose from. Whether you're hosting a conference or meeting or simply working remotely, these properties are equipped with the amenities you need to be productive.
What is there to do in Southwest Illinois near my business-friendly hotel?
Southwest Illinois has so much to do and see, it can be difficult to decide where to begin. If you're spending a few days in Alton for work, National Great Rivers Museum is a hit with travellers.

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