A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Spa Hotels & Resorts in Southern Indiana from AU$124

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Check availability on Southern Indiana Spa Hotels

Tonight
26 Oct - 27 Oct
Tomorrow
27 Oct - 28 Oct
This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Southern Indiana hotels with a spa

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A modern bathroom with a shower, a sink, and a large mirror.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A steam fountain in a brick alleyway.

1. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness centre in city centre Louisville.
AU$262
includes taxes & fees
22 Nov - 23 Nov
21c Museum Hotel Louisville
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A modern hotel room with a large window, a sofa, a red armchair, and a small table.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.

2. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
AU$228
includes taxes & fees
8 Nov - 9 Nov
Galt House Hotel Trademark Collection by Wyndham
A restaurant with round tables, chairs, chandeliers, and a bar area.
A spacious lobby with a geometric chandelier, a reception desk, and a red accent wall.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.
A hot tub with a pool, indoor seating area, and a view of the pool.

3. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
AU$124
includes taxes & fees
24 Nov - 25 Nov
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A modern interior with a fireplace, bookshelves, and seating areas.
A lobby with a marble floor, a reception desk, and a large chandelier.

4. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
AU$340
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A treatment room with a massage table, a desk with a computer, and a large mirror.
A large, multi-story hotel with a prominent dome and arched windows, featuring a well-lit entrance and landscaped gardens.
A poolside area with lounge chairs and a towel with a monogram.
A golf course with a flag, a sand bunker, and a building in the background.

5. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
AU$185
includes taxes & fees
26 Nov - 27 Nov
Belterra Casino Resort
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A spacious indoor area with a staircase, a vending machine, and a business center sign.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.
A hotel room with a bed, desk, chair, and a green accent wall.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalise your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness centre.
AU$129
includes taxes & fees
25 Nov - 26 Nov
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A cozy room with a wooden wall, a sofa, and a dining table.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.
A modern bathroom with a shower, a vanity with a sink, and a toilet. There are wooden shelves and a vase with flowers on the vanity.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cosy bed and breakfast retreat with a steamy spa pool, rejuvenating spa services, and a peaceful garden sanctuary.
AU$522
includes taxes & fees
27 Oct - 28 Oct
Pillow and Paddock B&B
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Choose what matters most at spa hotels in Southern Indiana

Pool
Breakfast included
Spa pool
4 stars
5 stars

Top Southern Indiana Hotel Reviews

Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

10/10 Excellent
"Rooms were very clean and spacious, best out of all were the staff members, very polite, helpful, great customer service, very attentive to needs and comfort."
Edward W 3-night trip
Posted 7 hours ago
Drury Inn & Suites Evansville East
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

10/10 Excellent
"We’ve been in probably 15 medium-priced hotels on this vacation. This was BY FAR the best. Breakfast was phenomenal!! And it was the little things—better cereal variety, better granola, better sausage and eggs ( not the premade scrambled)"
Joseph 1-night trip
Posted 8 hours ago
Hampton Inn New Albany Louisville West
Hampton Inn Evansville/Airport

Hampton Inn Evansville/Airport

10/10 Excellent
"H"
robert 1-night trip
Posted 5 days ago
Hampton Inn Evansville/Airport
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent
"remodeled recently. very clean. nice. comfy bed..at least for us. quiet.. but we were at end of the hall. room had plenty of space. nice long bathroom counter for toiletries etc. that was outside of tub and potty area. plenty of choices for breakfast. employees friendly. would definitely stay again!!"
Marilyn 1-night trip
Posted 12 days ago
Ramada by Wyndham Sellersburg/Louisville North

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