Spa Hotels & Resorts in Southern Illinois

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Best Southern Illinois Spa Hotels

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (374)
"Very nice room, nice scenery not an interstate running thru it"
Walker's Bluff Casino Resort

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"It was right off the interstate with lots of restaurant options "
The price is AU$162
includes taxes & fees
19 Oct - 20 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

1895 Washington Hotel

3.0 star property
9.2 out of 10, Wonderful, (378)
"An absolutely charming B&B with a great history."
1895 Washington Hotel

Arthur's Country Inn

2.5 star property
8.4 out of 10, Very good, (129)
"We loved this Inn it was a unique experience in comparison to modern hotels but definitely a nice change. "
The price is AU$178
includes taxes & fees
4 Oct - 5 Oct
Arthur's Country Inn

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1001)
"Beautiful hotel with friendly staff!"
The price is AU$339
includes taxes & fees
5 Oct - 6 Oct
Ameristar Casino Resort and Spa

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1393)
"Wonderful stay! "
The price is AU$293
includes taxes & fees
2 Nov - 3 Nov
21C Museum Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1000)
"Beautiful stay at the four seasons! "
The price is AU$752
includes taxes & fees
26 Oct - 27 Oct
Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (550)
"Service is exceptional!!!"
The price is AU$1,076
includes taxes & fees
2 Nov - 3 Nov
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southern Illinois

Find out more about Southern Illinois

Top Southern Illinois attractions for a relaxing vacation

Southern Illinois offers a delightful mix of relaxation and adventure, perfect for travellers seeking hotel spas. Begin your journey in the stunning Shawnee National Forest, where you can explore breathtaking landscapes and enjoy activities like hiking the famed Garden of the Gods. After a day of adventure, unwind at one of the local spa hotels that offer rejuvenating treatments inspired by nature. Don't miss the chance to visit the charming town of Carbondale, known for its vibrant arts scene and a plethora of dining options that cater to all tastes, providing the perfect backdrop for a relaxing evening after a day of exploration. Wine enthusiasts will appreciate a visit to the nearby wineries of the Shawnee Hills Wine Trail, where you can indulge in tastings while soaking in the picturesque views. For a unique experience, take a leisurely boat ride on the serene waters of the Cache River State Natural Area, where you can reconnect with nature. Staying in the quaint town of Makanda, with its artisanal shops and laid-back vibe, allows you to enjoy a peaceful retreat, complemented by spa facilities that cater to your every need, ensuring you leave feeling pampered and revitalised.

Top Southern Illinois Hotel Reviews

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