Photo by Southernmost Illinois Tourism Bureau
Family Hotels & Resorts in Southern Illinois from AU$98
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Best Southern Illinois Family Hotels
Hampton Inn & Suites Effingham
Effingham
9.6 out of 10, Exceptional, (671)
"Great place. Clean and very comfortable rooms. Great breakfast"
Luis
The price is AU$173
includes taxes & fees
12 Dec - 13 Dec
Comfort Suites Mount Vernon
Mount Vernon
9.0 out of 10, Wonderful, (1006)
"Rooms have been painted great breakfast close to interstate and restaurants"
Stephen
The price is AU$186
includes taxes & fees
7 Dec - 8 Dec
Drury Inn & Suites Marion
Marion
9.4 out of 10, Exceptional, (1000)
"Great hotel and very clean "
Jose
The price is AU$118
includes taxes & fees
22 Dec - 23 Dec
Drury Plaza Hotel Mt. Vernon
Mount Vernon
9.6 out of 10, Exceptional, (1561)
"Great place to stay. Check in is easy and the hotel people are very nice."
Duane
The price is AU$161
includes taxes & fees
11 Dec - 12 Dec
Holiday Inn Express Metropolis by IHG
Metropolis
8.4 out of 10, Very good, (1002)
"great stay"
Carol
The price is AU$153
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Effingham
Effingham
9.2 out of 10, Wonderful, (1002)
"Clean room, excellent location, pet friendly. Would definitely book again. "
Misty
The price is AU$157
includes taxes & fees
28 Dec - 29 Dec
Super 8 by Wyndham Mt. Vernon IL
Mount Vernon
7.8 out of 10, Good, (1000)
"Clean comfortable room and bed. Great location to many restaurants and shopping. "
Patricia
The price is AU$102
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Centralia Hotel & Suites
Centralia
9.6 out of 10, Exceptional, (597)
"Very beautiful place to stay "
Valerie
The price is AU$204
includes taxes & fees
1 Jan - 2 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews
Comfort Suites Mount Vernon
10/10 Excellent
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