Business Hotels & Resorts in South Carolina Midlands from AU$105

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Check availability on South Carolina Midlands Business Hotels

Tonight
8 Dec - 9 Dec
Tomorrow
9 Dec - 10 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Best South Carolina Midlands Business Hotels

Room, 2 Queen Beds, Non Smoking
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very good, (1407)
"The best stay"
United States
Terez
The price is AU$125
includes taxes & fees
10 Dec - 11 Dec
Baymont by Wyndham Santee
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.8 out of 10, Excellent, (2486)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is AU$105
includes taxes & fees
10 Dec - 11 Dec
Howard Johnson by Wyndham Florence
Free continental breakfast
Holiday Inn Express & Suites Newberry by IHG

Holiday Inn Express & Suites Newberry by IHG

2.5 star property
Newberry
9.0 out of 10, Wonderful, (632)
"Room was clean staff was great !"
United States
R Scott
The price is AU$138
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express & Suites Newberry by IHG
Breakfast and dinner served
Courtyard by Marriott Columbia Cayce

Courtyard by Marriott Columbia Cayce

3.0 star property
Cayce
9.0 out of 10, Wonderful, (651)
"Room was clean. staff was very pleasant. Cafe / Bistro was good and convenient. Easy parking on site."
United States
joan
The price is AU$169
includes taxes & fees
23 Dec - 24 Dec
Courtyard by Marriott Columbia Cayce
Property entrance
Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel

3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (708)
"It was a very clean and beautiful lace to stay. We were there for our honeymoon "
United States
Tracy
The price is AU$183
includes taxes & fees
4 Jan - 5 Jan 2026
Inn on the Square, an Ascend Collection Hotel
Lobby
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1005)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
The price is AU$173
includes taxes & fees
15 Dec - 16 Dec
Tru by Hilton Orangeburg
Front of property – evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property
Florence
8.8 out of 10, Excellent, (1002)
"Great stay"
United States
Michaelle
The price is AU$169
includes taxes & fees
15 Dec - 16 Dec
Hyatt Place Florence Downtown
Lobby
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3.0 star property
Columbia
9.0 out of 10, Wonderful, (1867)
"This property and their staff were lovely!"
United States
Mary
The price is AU$134
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Columbia/Harbison
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1160)
"Enjoyed our stay there. "
United States
Cathy
The price is AU$171
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Florence Center Area
Exterior
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 star property
Cayce
8.2 out of 10, Very good, (1005)
"Clean and friendly staff easy check in and out"
United States
Leslie
The price is AU$151
includes taxes & fees
4 Jan - 5 Jan 2026
Country Inn & Suites by Radisson, Columbia Airport, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Midlands Hotel Reviews

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

10/10 Excellent
"Excellent, staff was super"
Wendy 1-night trip
Posted 4 days ago
Hilton Garden Inn Columbia/Harbison

Frequently asked questions

How much do business-friendly hotels in South Carolina Midlands cost?
Business-friendly hotels in South Carolina Midlands range between AU$105 and AU$183 per night. This means you can book a property with welcome amenities like workspaces and WiFi at a price that's easy on your wallet. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in South Carolina Midlands?
South Carolina Midlands has 268 business-friendly hotels to choose from. Whether you're catching up with clients or working remotely, these properties come with the amenities you need to keep you productive and comfortable.
What is there to do in South Carolina Midlands near my business-friendly hotel?
Whatever you're into, there are lots of attractions and things to entertain you in South Carolina Midlands. If you're on your way to Columbia, check out Riverbanks Zoo and Garden, Township Auditorium and South Carolina State Museum. Organising a stay in Rock Hill? Main Street Childrens Museum, Rock Hill Sports & Event Centre and Cherry Park are popular attractions in this city.

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