A monument with a statue on top, in front of a large building with columns.

Business Hotels & Resorts in South Carolina Midlands from AU$126

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on South Carolina Midlands Business Hotels

Tonight
1 Oct - 2 Oct
Tomorrow
2 Oct - 3 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for South Carolina Midlands business-friendly hotels

An outdoor patio with a stone fire pit, seating, and a covered area with lights.
A hotel room with a modern design, featuring a large bed, a desk, and a seating area with a tray table.
A modern hotel lobby with a curved sofa, dining area, and a kitchen in the background.
A modern kitchen with dark wood cabinets, a white countertop, and various kitchen appliances.

1. Springhill Suites by Marriott Columbia near Fort Jackson

Springhill Suites by Marriott Columbia near Fort Jackson
Columbia
United States
Carlos
AU$162
includes taxes & fees
25 Oct - 26 Oct
Springhill Suites by Marriott Columbia near Fort Jackson
A modern kitchen with a long counter, a coffee machine, and a refrigerator.
A reception area with a cityscape mural, two reception desks, and a modern design.
A hotel named La Quinta with a modern architectural design, featuring a prominent sun logo and multiple windows.
A hotel room with two beds, a desk, a chair, and a TV.

2. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Columbia
United States
Todd
AU$164
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".
A modern lounge area with a blue sofa, hanging chairs, and a table with chairs.

3. Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone
Columbia
United States
Kim
AU$160
includes taxes & fees
1 Nov - 2 Nov
Tru By Hilton Columbia Greystone
A modern bar area with a central island, bar stools, and a television.
A hotel room with two beds, a sofa, a desk, and a large window.
A spacious lobby with a reception desk, seating area, and large windows allowing natural light.
A modern hotel room with a sectional sofa, a small table, and a TV mounted on the wall.

4. Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista
Downtown Columbia
United States
Jeanne
AU$205
includes taxes & fees
1 Nov - 2 Nov
Cambria Hotel Columbia Downtown The Vista
An outdoor seating area with wicker chairs and a glass table, a fire feature, and a stone wall.
A reception area with a wooden reception desk, a blue and orange chevron-patterned carpet, and a wall with a welcome sign.
A modern hotel lobby with blue upholstered chairs, round tables, a central bar area, and a wooden accent wall.
A Hampton Inn & Suites with a modern design, featuring a stone facade and a blue accent wall.

5. Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

Hampton Inn & Suites Columbia/Southeast-Ft. Jackson
Columbia
United States
Devine
AU$168
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Columbia/Southeast-Ft. Jackson
A hotel entrance with a covered walkway, stone pillars, and a glass door entrance.
A modern living room with a gray sofa, two chairs, a coffee table, and a large window offering a view of greenery.
A snack and beverage vending machine with various snacks and drinks.
A hotel room with a large bed, a bedside table with a lamp, a small table with a plant, a sofa with cushions, and a view of the city through a large window.

6. Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG

Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
Columbia
United States
Jose Santos
AU$158
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
A hotel room with a large bed, a desk, a chair, a window, and a wall-mounted lamp.
A buffet with various food items, including omelets and baked goods, served in metal containers.
An indoor swimming pool with a diving board, tiled flooring, and a seating area with tables and chairs.
A coffee station with two espresso machines, a coffee grinder, and various coffee pods and cups.

7. Holiday Inn Express & Suites Columbia-Fort Jackson by IHG

Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
Columbia
United States
Leleith
AU$173
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
A spacious lobby with a central seating area, a shop, and large potted plants.
A spacious lobby with a high ceiling, multiple hanging pendant lights, and striped curtains.
A room with a fireplace, bookshelves, two chairs, and a coffee table.
A Hilton Garden Inn with a well-lit entrance, a covered waiting area, and a visible parking lot.

8. Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison
Columbia
United States
Ann Marie
AU$138
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden Inn Columbia/Harbison
A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.
A modern kitchen area with a long counter, various food items, and a chalkboard with food-related drawings.
A reception desk with a "Welcome to the Palmetto State" sign, a wooden accent wall, a minibar, and a digital kiosk.
A hotel room with a bed, desk, chair, air conditioning unit, and a window with a view of trees.

9. Hampton Inn & Suites Lexington Columbia

Hampton Inn & Suites Lexington Columbia
Lexington
United States
LISA
AU$193
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Lexington Columbia
A modern interior with a reception desk, a bench, and a wall with a bulletin board.
A gym with exercise equipment, a treadmill, and a wall with a colorful mural.
A delivery drop area with a wooden shelf holding bags and a locker area with numbered lockers.
A modern laundry room with a table, chairs, and washing machines.

10. LivSmart Studios by Hilton Columbia Greystone

LivSmart Studios by Hilton Columbia Greystone
Columbia
United States
Robertson
AU$187
includes taxes & fees
11 Oct - 12 Oct
LivSmart Studios by Hilton Columbia Greystone
View all properties

Top South Carolina Midlands Hotel Reviews

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good
"For the price it’s a very nice hotel. My only complaint is that southern humidity seems to have ruined some of the carpeting and doors in the rooms."
Shirleen 1-night trip
Posted 1 hour ago
Howard Johnson by Wyndham Florence
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

8/10 Good
"The breakfast was good Only one elevator worked our entire stay. Room was supposed to be cleaned every other day, which it wasn’t. When I got into the room there was barely any toilet paper. I had to ask for a roll. A few days later they came to clean my room and still left the other toilet roll dispenser empty. I had to again request toilet paper. I travel frequently, that was the first time I had to request toilet paper."
Joann 7-night trip
Posted 4 hours ago
Hilton Garden Inn Columbia/Harbison

Frequently asked questions

How much do business-friendly hotels in South Carolina Midlands cost?
Business-friendly hotels in South Carolina Midlands range between AU$126 and AU$210 per night. This means you can book a property with welcome amenities like workspaces and WiFi at a price that's easy on your wallet. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in South Carolina Midlands?
South Carolina Midlands has 268 business-friendly hotels to choose from. Whether you're catching up with clients or working remotely, these properties come with the amenities you need to keep you productive and comfortable.
What is there to do in South Carolina Midlands near my business-friendly hotel?
Whatever you're into, there are lots of attractions and things to entertain you in South Carolina Midlands. If you're on your way to Columbia, check out Riverbanks Zoo and Garden, Township Auditorium and South Carolina State Museum. Organising a stay in Rock Hill? Main Street Childrens Museum, Rock Hill Sports & Event Centre and Cherry Park are popular attractions in this city.

Explore a world of travel with Expedia