Top Hotels Near Sioux Empire Medical Museum in Sioux Falls from AU$81

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
15 Jan - 16 Jan
Tomorrow
16 Jan - 17 Jan
This weekend
16 Jan - 18 Jan
Next weekend
23 Jan - 25 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sioux Empire Medical Museum hotels

Interior detail

Hotel On Phillips

Hotel On Phillips
2.5 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
9.6 out of 10, Exceptional, (1,332 reviews)
"Nice place to stay"
United States
Andy
Hotel On Phillips
Exterior detail

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls
3.0 star property
Mall District, 2.8 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,003 reviews)
"The stay was fantastic!"
United States
Cleo
Clubhouse Hotel Suites Sioux Falls
Meeting facility

Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown
4.0 star property
Downtown Sioux Falls, 2.5 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (166 reviews)
"Room was clean and the beds were pretty comfortable. The hotel is in a great location. Only issue, it’s way to close to Smithfield pork processing plant."
United States
Brett
The price is AU$232
includes taxes & fees
31 Jan - 1 Feb
Canopy By Hilton Sioux Falls Downtown
Exterior

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (1,003 reviews)
"It was a very nice stay. "
United States
Lenore
The price is AU$177
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn Sioux Falls
Porch

Historic Victorian Inn

Historic Victorian Inn
3.0 star property
Cathedral, 1.5 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (56 reviews)
"It was a great place to stay and super interesting."
United States
Kathy
The price is AU$246
includes taxes & fees
20 Jan - 21 Jan
Historic Victorian Inn
Meeting facility

Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown
3.0 star property
Downtown Sioux Falls, 2.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (893 reviews)
"Friendly front desk staff, clean room, great location, safe "
United States
Hannah
The price is AU$180
includes taxes & fees
22 Jan - 23 Jan
Hilton Garden Inn Sioux Falls Downtown
Exterior

Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
Downtown Sioux Falls, 1.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,000 reviews)
"Beds and pillows were comfortable"
United States
Lori
The price is AU$159
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn Sioux Falls-City Centre by IHG
Exterior

Country Inn & Suites by Radisson, Sioux Falls

Country Inn & Suites by Radisson, Sioux Falls
3.0 star property
Downtown Sioux Falls, 2 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (1,179 reviews)
"It was a great place to stay!"
United States
Trinity
The price is AU$143
includes taxes & fees
18 Jan - 19 Jan
Country Inn & Suites by Radisson, Sioux Falls
Exterior

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
Mall District, 3.1 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (1,000 reviews)
"The breakfast was amazing and plenty of options with cold food and hot. The staff were great too and so was our room. "
United States
JACKIE
The price is AU$216
includes taxes & fees
17 Jan - 18 Jan
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Lobby

Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
8.6 out of 10, Excellent, (1,001 reviews)
"Clean and friendly "
United States
Eddie
The price is AU$176
includes taxes & fees
25 Jan - 26 Jan
Sheraton Sioux Falls Hotel & Convention Center
Basic Studio, 1 King Bed

Valley Inn

Valley Inn
2.5 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,000 reviews)
"Clean room Friendliness Great location for us "
United States
Rhonda or doug
Valley Inn
Suite 2 Queens, Recliner, Pullout Sofa

The Center Inn

The Center Inn
2.5 star property
All Saints, 2.4 km from Sioux Empire Medical Museum
8.4 out of 10, Very good, (713 reviews)
"Room and staff were great. "
United States
Annette
The Center Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
Northwest Sioux Falls, 2.9 km from Sioux Empire Medical Museum
7.8 out of 10, Good, (1,489 reviews)
"Staff was very courteous. Had a pleasant stay"
United States
Tamela
The price is AU$108
includes taxes & fees
18 Jan - 19 Jan
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
50-inch flat-screen TV with cable channels, fireplace, Netflix

Historic Twin Tudors Inn

Historic Twin Tudors Inn
3.0 star property
1.4 km from Sioux Empire Medical Museum
8.8 out of 10, Excellent, (3 reviews)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveller
The price is AU$457
includes taxes & fees
18 Jan - 19 Jan
Historic Twin Tudors Inn
Pool

Ramada by Wyndham Sioux Falls Arpt & Suites

Ramada by Wyndham Sioux Falls Arpt & Suites
2.0 star property
Northwest Sioux Falls, 3 km from Sioux Empire Medical Museum
7.0 out of 10, Good, (52 reviews)
"Very friendly at check in. Great service at bar."
United States
Chris
Ramada by Wyndham Sioux Falls Arpt & Suites
Exterior

WoodSpring Suites Sioux Falls

WoodSpring Suites Sioux Falls
2.5 star property
2.8 km from Sioux Empire Medical Museum
5.2 out of 10, (60 reviews)
"I didn't know smoking rooms still existed and was less expensive than all non-smoking options. Room was very large, 2 burner stove & full size refrigerator. Clean, quiet, comfortable. Coupled with affordable I know where I'm staying every time I visit Sioux Falls "
United States
Clyde
The price is AU$141
includes taxes & fees
16 Jan - 17 Jan
WoodSpring Suites Sioux Falls
Double Room, 2 Queen Beds

Highpoint Hotel

Highpoint Hotel
3.0 star property
University Heights, 0.2 km from Sioux Empire Medical Museum
The price is AU$225
includes taxes & fees
24 Jan - 25 Jan
Highpoint Hotel
Lobby

Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls
2.0 star property
2.6 km from Sioux Empire Medical Museum
5.6 out of 10, (1,000 reviews)
"Good room for the price."
United States
Michael
The price is AU$81
includes taxes & fees
26 Jan - 27 Jan
Ramada by Wyndham Sioux Falls
Terrace/patio

Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South
3.0 star property
Mall District, 3.7 km from Sioux Empire Medical Museum
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay!"
United States
Nick
The price is AU$195
includes taxes & fees
22 Jan - 23 Jan
Hyatt Place Sioux Falls South
Exterior

Holiday Inn & Suites Sioux Falls - Airport by IHG

Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
Northwest Sioux Falls, 3.4 km from Sioux Empire Medical Museum
9.2 out of 10, Wonderful, (850 reviews)
"Clean Room. Beautiful pool and hot tub area. Great location. "
United States
Carissa
The price is AU$185
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn & Suites Sioux Falls - Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sioux Empire Medical Museum Hotel Reviews

AeroStay Hotel

AeroStay Hotel

10/10 Excellent
"Great lady"
scott 1-night trip
Posted 5 days ago
AeroStay Hotel

Hotels near other Sioux Empire Medical Museum attractions

Great Plains Zoo

4.3/5 (74 reviews)
Why not meet the animals who live at Great Plains Zoo during your holiday in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
See properties

University of Sioux Falls

4.1/5 (170 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 125 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Valley Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free parking and free WiFi. Another good choice is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center, located just 0.1 mi (0.2 km) away.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 125 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Center for Western Studies and Old Courthouse Museum feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can wander around Falls Park, Sherman Park or Fawick Park if you want a dose of fresh air.