Santa Cruz Travel Guide
Tourist Guide
Visit Santa Cruz
Popular places to visit
Royal Alcázar of Seville
Once a Moorish fort, this architectural gem is now the oldest functioning palace in Europe.
Giralda Tower
This ornate belfry has an interesting past; before being one of the Cathedral's towers, it was a minaret.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Cabildo Catedral
Stop by a 16th-century meeting room inside the Cathedral of Seville that is stunningly decorated with religious paintings, sculptures and reliefs.
Triunfo Plaza
From this ancient and picturesque square, access some of the oldest and most impressive buildings in Seville, including the world’s largest gothic cathedral.
University of Seville
Explore the campus of University of Seville during your travels in Paseo de Las Delicias. Visit the stunning cathedral and shops in this culturally rich area.
Activities
Cathedral & Alcázar of Seville Guided Tour Combo
Sevilla Food Tour: Tapas, Wine, History & Traditions
Guadalquivir River Criuse Tour
Alone in the Alcazar: Exclusive Early Access Guided Tour
Ticket for Casa de la Guitarra Flamenco Show
Our pick of the best Santa Cruz Hotel Deals
Hotel Fernando III
Quiet and clean and the neighborhood was a joy and central.
Reviewed on 6 Mar 2026
Las Casas de la Judería, Sevilla Historic City Center
Thoroughly enjoyable few days. The hotel is quite unique, full of charm and in a very good location. Loved having a late drink in the piano bar after a full day exploring. Our room was ready so made available to us before check in time. We were given a complementary bottle of cave on day of arrival. ...
Reviewed on 6 Mar 2026
Hotel Rey Alfonso X
Fantastic location - a short walk to the Alcázar, Seville Cathedral and the Plaza de Espana. The rooms are spacious and the breakfast selection is excellent. The only downside was the air conditioning was okay but not great. I would recommend this hotel.
Reviewed on 5 Mar 2026
Hotel Murillo
Fantastic location
Reviewed on 3 Mar 2026
Hotel Amadeus Sevilla
Fabulous location and lovely property. We thoroughly enjoyed our stay. We never took a taxi and all of our chosen destinations were within 10-20 minute walk.
Reviewed on 7 Mar 2026
Hotel Doña Maria
Great service beautiful hotel
Reviewed on 6 Mar 2026
Other neighbourhoods around Santa Cruz
El Arenal
Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Paseo de Cristóbal Colón.
San Bartolomé
Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.
Alfalfa
Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.
Historical Center
Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.
La Florida
The restaurants and shopping are a few reasons travellers visit La Florida. Want to see more of the surrounding area? Murillo Gardens and Pilate's House are a few top sights nearby.
San Bernardo
Even though there aren't top sights in San Bernardo, you can explore the larger area and take in top sights like Murillo Gardens. Jump on the metro at Prado San Sebastián Tram Stop to see more of the city.
