
Santa Cruz Holidays
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Your Santa Cruz Holiday
Booking a Santa Cruz holiday package is a good way to become acquainted with this unique neighbourhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz holiday looks like, you can turn it into reality with Expedia.
Our guide on where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz

Historical Center
7 out of top 10 points of interest in this area
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Our pick of the best Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
The price is AU$212 per night from 29 July to 30 July
AU$212
29 July - 30 July
includes taxes & fees
9.2/10 Wonderful! (1,014 reviews)
"Staff were so friendly as we checked in. We were given a list of nearby recommendations which really helped us explore the area. Actual building was so authentic and picturesque; I’ve never stayed anywhere so beautiful! Rooms were lovely and clean. Would highly recommend."
Reviewed on 12 July 2026

Hotel Murillo
Calle Lope de Rueda, 7-9 Seville Seville
The price is AU$71 per night from 22 July to 23 July
AU$71
22 July - 23 July
includes taxes & fees
8.8/10 Excellent! (1,004 reviews)
"Hotel centrico, comodo, muy bonito. Todo estuvo a la altura. Excelente."
Reviewed on 15 July 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
The price is AU$676 per night from 12 Aug to 13 Aug
AU$676
12 Aug - 13 Aug
includes taxes & fees
9.4/10 Exceptional! (1,004 reviews)
"Hôtel splendide, luxueux et très bien situé. À proximité de tous les sites majeurs, les restos, les boutiques et les grands parcs. L'hôtel rempli parfaitement sa promesse : beauté, confort et raffinement. Nous avons eu de très bonnes recommandations de restaurants, conformes à ce que nous recherchions. ..."
Reviewed on 11 July 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Stay near popular Santa Cruz attractions
Activities

Cathedral & Alcázar of Seville Guided Tour Combo
AU$50
per adult
90% of travellers recommend

Guadalquivir River Criuse Tour
AU$31
per adult
80% of travellers recommend

Granada Day Trip from Seville with Alhambra Guided Tour Included
AU$279
per adult
86% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

















