Search Santiago Sur hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
31 July - 1 Aug
Tomorrow
1 Aug - 2 Aug
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santiago Sur

Hotel Gran David
Relax by the serene pool surrounded by lush palm trees and lounge chairs.

Hotel Gran David

3.5 star property
8.4 out of 10, Very good, (317)
"Excellent place for family"
Hotel Gran David
Hotel Mykonos Panama
Relax by the pool with a refreshing drink and a good book.

Hotel Mykonos Panama

3.5 star property
8.8 out of 10, Excellent, (521)
"Great location and service."
The price is AU$131
includes taxes & fees
4 Aug - 5 Aug
Hotel Mykonos Panama
Casa Morrillo
Enjoy a serene coastal escape with access to a natural beach and surrounding dense vegetation.

Casa Morrillo

2.5 star property
10.0 out of 10, Exceptional, (1)
"Amazing location. Great staff and owners."
The price is AU$165
includes taxes & fees
2 Aug - 3 Aug
Casa Morrillo
Cabañas Palma Real
Relax by the serene pool surrounded by lush greenery and a wooden pergola.

Cabañas Palma Real

3.0 star property
The price is AU$117
includes taxes & fees
2 Aug - 3 Aug
Cabañas Palma Real
Bambuda Santa Catalina
Enjoy dining and socializing in the outdoor seating area, overlooking the ocean.

Bambuda Santa Catalina

2.5 star property
9.4 out of 10, Exceptional, (40)
"Great place to stay while visiting area and Coiba National Park"
Bambuda Santa Catalina
Hotel y Restaurante Mama Ines
Relax in a tranquil beachside setting with comfortable lounge chairs and a shaded table.

Hotel y Restaurante Mama Ines

3.0 star property
8.6 out of 10, Excellent, (15)
"Nice people and cute hotel!"
Hotel y Restaurante Mama Ines
Hotel Hibiscus Garden / Jardin De Papos
Enjoy a serene beach experience with a tranquil ocean view surrounded by palm fronds.

Hotel Hibiscus Garden / Jardin De Papos

2.5 star property
6.4 out of 10, (14)
"The online 1-star rating is not really justified. Although basic, this place is worth the $55 fee. The Hotels.com experience is to be avoided, they overcharged on the rate. The room was basic, the bed below average, but seeing the many species and number of sea birds in the early morning is a treat. The dirt driveway to the site is a biet of a pain."
The price is AU$68
includes taxes & fees
2 Aug - 3 Aug
Hotel Hibiscus Garden / Jardin De Papos
Hotel Galería
Relax by the pool in a tranquil setting, complete with a gazebo and comfortable lounge seating.

Hotel Galería

3.0 star property
8.4 out of 10, Very good, (192)
"SC"
The price is AU$109
includes taxes & fees
4 Aug - 5 Aug
Hotel Galería
Villa Coco
Relax by the serene pool surrounded by lush greenery, perfect for a leisurely swim or float.

Villa Coco

2.5 star property
9.2 out of 10, Wonderful, (47)
"Great customer service - beautiful property "
The price is AU$222
includes taxes & fees
3 Aug - 4 Aug
Villa Coco
Hotel Santa Catalina Panama
Relax by the oceanfront pool surrounded by lush greenery and trees.

Hotel Santa Catalina Panama

3.0 star property
9.0 out of 10, Wonderful, (125)
"The site has a restaurant overlooking an infinity pool, overlooking a great surfing location. Staff are friendly and accommodating, and the owners both reached out to welcome us."
Hotel Santa Catalina Panama
Punta Duarte Garden Inn
Relax by the serene pool surrounded by lush tropical vegetation and a dense forested backdrop.

Punta Duarte Garden Inn

3.0 star property
9.2 out of 10, Wonderful, (35)
"The hotel is located on a beautiful bluff overlooking the ocean. Our only negative review is the 2 mile dirt road to get to the beautiful location. "
The price is AU$169
includes taxes & fees
5 Aug - 6 Aug
Punta Duarte Garden Inn
Kooteja Santa Catalina KAÏSA
Relax in a serene outdoor space with a hot tub and seating area surrounded by lush greenery.

Kooteja Santa Catalina KAÏSA

3.0 star property
8.0 out of 10, Very good, (1)
"The system to get in the cabin is pretty clever, and the place looked nice. Yet, I would have appreciated instructions on where to leave the money and also if the grass around the cabin was lower or cut. "
The price is AU$139
includes taxes & fees
27 Aug - 28 Aug
Kooteja Santa Catalina KAÏSA
La Chamba Surf House
Corridors lead to rooms with large windows offering views of lush outdoor areas.

La Chamba Surf House

3.0 star property
The price is AU$60
includes taxes & fees
2 Aug - 3 Aug
La Chamba Surf House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santiago Sur

Check out Mariato Beach—just one of the sights to explore around Santiago Sur.

See all hotels in Santiago Sur

Top Santiago Sur Hotel Reviews

Hotel Santa Catalina Panama

Hotel Santa Catalina Panama

10/10 Excellent
"The site has a restaurant overlooking an infinity pool, overlooking a great surfing location. Staff are friendly and accommodating, and the owners both reached out to welcome us."
Virginia 2-night trip
Posted 2 days ago
Hotel Santa Catalina Panama

Frequently asked questions

What's the best place to stay in Santiago Sur?

Based on our traveller data, Cabañas Palma Real is one of the top choices for your stay. This cabin offers an outdoor pool and free parking. Other good choices for your visit to the area are Hotel Gran David and Hotel Mykonos Panama. See all available top hotels, or vacation rentals in Santiago Sur.

What are some of the best holiday rentals that Santiago Sur has to offer?

Charming 1-Bedroom Beachfront Hotel With Pool: This holiday home rental outside of Santiago Sur has air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santiago Sur.

If I need to cancel my hotel reservation in Santiago Sur, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Sur.

What is staying in Santiago Sur like?

Travellers to Santiago Sur will find plenty to explore and enjoy. There are 54 hotels and other accommodation options in the surrounding area. Find out more about Santiago Sur.

What should I see while I'm in Santiago Sur?

Places to visit in the wider area include Mariato Beach, Torio Beach and Lagartero Beach. Additionally, you'll find Torio Falls in the area. Take a look at what more there is to see and do in Expedia's Santiago Sur guide.

What's the seasonal weather like in Santiago Sur?

The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santiago Sur are October, August, June and November, with each month seeing an average of 447 mm of rainfall.