Santa Isabel Holiday Rentals

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Holiday Rentals in Santa Isabel

Coker Palace

2.0 star property
Arecibo
The price is AU$264
includes taxes & fees
9 Dec - 10 Dec
Coker Palace

Nature's Lodge Escape

Sabana Grande
The price is AU$128
includes taxes & fees
9 Dec - 10 Dec
Nature's Lodge Escape

Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat

Isabela
10.0 out of 10, Exceptional, (1)
"Excellent!"
United States
Heriberto M.
The price is AU$210
includes taxes & fees
9 Dec - 10 Dec
Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat

Ventana al Atlantico at Arecibo 681 Ocean Drive

2.5 star property
Arecibo
7.0 out of 10, Good, (249)
"Is a nice place to relax and stepping out from your normal life routine. The pool and the beach so near are the best combo. The staff is very friendly and helpful. Love the place. "
United States
Reinaldo E.
The price is AU$231
includes taxes & fees
9 Dec - 10 Dec
Ventana al Atlantico at Arecibo 681 Ocean Drive

Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach

2.0 star property
Quebradillas
The price is AU$121
includes taxes & fees
9 Dec - 10 Dec
Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach

Hacienda Vista Del Rio 1

Orocovis
The price is AU$296
includes taxes & fees
10 Dec - 11 Dec
Hacienda Vista Del Rio 1

Cozy 2-bedroom apartment in charming Arecibo with WiFi, AC

2.0 star property
Arecibo
10.0 out of 10, Exceptional, (2)
"Nice place to stay, sleep and go out!! "
United States
Rosa
The price is AU$283
includes taxes & fees
10 Dec - 11 Dec
Cozy 2-bedroom apartment in charming Arecibo with WiFi, AC

Casa vacacional en Arenales Isabela

3.5 star property
Isabela
9.0 out of 10, Wonderful, (48)
"Good amount of space, beds & pillows were comfortable. Hosts were responsive. House was clean. My only complaint was that power went out for about 5 hours and it was hot! I also didn’t like that it was high up on a long road with many turns and barely visible street signs. This aside, it was fine with enough room for all."
United States
Lillian
The price is AU$266
includes taxes & fees
7 Jan - 8 Jan 2026
Casa vacacional en Arenales Isabela

Studio in town w/ peaceful and private area - Pet-Friendly

Rio Pietro
The price is AU$237
includes taxes & fees
9 Dec - 10 Dec
Studio in town w/ peaceful and private area - Pet-Friendly

Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

Utuado
10.0 out of 10, Exceptional, (1)
The price is AU$315
includes taxes & fees
9 Dec - 10 Dec
Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

VSS La Puntilla Stylish Coastal Getaway Near Beach

Arecibo
The price is AU$274
includes taxes & fees
9 Dec - 10 Dec
VSS La Puntilla Stylish Coastal Getaway Near Beach

Cozy Apartment: Wake to Ocean Waves

2.0 star property
Hato Abajo
10.0 out of 10, Exceptional, (3)
"The view was stunning. The host was always very quick to respond. The beds were very comfortable. "
United States
Angie
The price is AU$310
includes taxes & fees
10 Dec - 11 Dec
Cozy Apartment: Wake to Ocean Waves

Casita Linda

2.5 star property
Arecibo
9.0 out of 10, Wonderful, (2)
"Angel worked us in on a same-day booking and met with us at 9:00pm for check and was truly a holiday life-saver (thanks to a different VRBO booking never responding on check in). Nice amenities and right next to ocean (more surfing spot rather than swimming, but pool was nice as well). With more times notice and some updates, this place could easily be 5 star. Again, super thanks to Angel for the last-minute accomodations."
United States
Justin
The price is AU$406
includes taxes & fees
31 Dec - 1 Jan 2026
Casita Linda

"Escape to Paradise at Arenales Vacation House: Your Dream Vacation Getaway!"

Arenales Altos
10.0 out of 10, Exceptional, (1)
"It is a great option for stay. Clean, confortable and quiet place"
United States
Carlos
The price is AU$216
includes taxes & fees
7 Jan - 8 Jan 2026
"Escape to Paradise at Arenales Vacation House: Your Dream Vacation Getaway!"

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Adjuntas
9.6 out of 10, Exceptional, (13)
"The Cozy Casita was the perfect little place to stay it was clean and set the perfect vacation vibes. The host was really nice and attentive, quick at responding. Would definitely do it again! "
United States
Jesse
The price is AU$440
includes taxes & fees
5 Jan - 6 Jan 2026
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Colombian Boricua Apartment 5 minutes from the beach luxury

2.0 star property
Quebradillas
The price is AU$123
includes taxes & fees
10 Dec - 11 Dec
Colombian Boricua Apartment 5 minutes from the beach luxury

VSS Rustic: Stylish & Relaxing Escape Near Beaches

2.0 star property
Arecibo
The price is AU$322
includes taxes & fees
15 Dec - 16 Dec
VSS Rustic: Stylish & Relaxing Escape Near Beaches

Arecibo Hotel 2105

2.0 star property
Arecibo
7.8 out of 10, Good, (10)
"The apartment was excellent for a family of 4 . It was very clean with all the appliances you would need to call it home. The process was simple and communication with a representative was excellent. Highly recommend."
United States
Alfredo
The price is AU$238
includes taxes & fees
16 Dec - 17 Dec
Arecibo Hotel 2105

Apartamento Vista Del Río #2

orocovis
Apartamento Vista Del Río #2

Beach Apartment in Isabela with AC, WIFI. Charming 2-bedroom

2.0 star property
Isabela
6.0 out of 10, (3)
" Dry nice Jackie’s response to my questions was slow!"
United States
Marie T.
The price is AU$212
includes taxes & fees
9 Dec - 10 Dec
Beach Apartment in Isabela with AC, WIFI. Charming 2-bedroom
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

Everything you need to know about Santa Isabel holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santa Isabel holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Isabel holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Isabel holiday rentals we have selected for you start as low as AU$231 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santa Isabel rentals

At Expedia, we put the best Santa Isabel holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Santa Isabel?

Yes, there are holiday rentals close to the most popular sights in Santa Isabel, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Isabel has to offer?

Casa vacacional en Arenales Isabela: This holiday home rental outside of Santa Isabel offers a terrace, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Arecibo Observatory, or get out into nature at a spot like Tanamá River. Camuy River Cave Park and Cueva Ventana are a couple of places you'll find in the wider area.

What are holiday rentals like in Santa Isabel?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Isabel. Holiday rentals offer extras such as hot tubs, fire pits and patios so you'll be comfy for your stay. If you're concerned about a sanitised environment, a holiday rental can offer a sense of privacy away from shared hotel lifts and busy concierge desks while still allowing you to travel. You'll also have more space in a holiday rental than in a traditional hotel, which makes a holiday rental a popular choice for family trips.