
Santa Cruz Holidays
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Your Santa Cruz Holiday
With a Santa Cruz holiday package, you can forget about planning hassles and simply focus on experiencing everything this thrilling destination has to offer. The best way to plan your trip to Santa Cruz is to begin with its most popular cities, which include Samaipata, Roboré and Camiri. Expedia is a one-stop shop when it comes to planning your Santa Cruz holiday. From flights and hotels, to activities and more, we're here to help you create a travel experience like no other.
Top destinations in Santa Cruz

Santa Cruz

San Javier
Santa Cruz Essential Information
Language | Spanish |
---|---|
Currency | Bolivian bolivianos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Viru Viru Intl. Airport (VVI) |
Top Sights | Amboró National Park, Santa Cruz Zoo and Lomas de Arena Regional Park |
Our pick of the best Santa Cruz Hotel Deals

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
San Martin Avenue Esq Street E - E, Santa Cruz
The price is AU$116 per night from 15 Aug to 16 Aug
AU$116
15 Aug - 16 Aug
9/10 Wonderful! (246 reviews)
"Everything thanks"
Reviewed on 31 Jul. 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455, Santa Cruz
The price is AU$188 per night from 25 Aug to 26 Aug
AU$188
25 Aug - 26 Aug
8.8/10 Excellent! (321 reviews)
"Always an amazing hotel"
Reviewed on 21 Jun. 2025

Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
The price is AU$67 per night from 25 Aug to 26 Aug
AU$67
25 Aug - 26 Aug
9.4/10 Exceptional! (47 reviews)
"The"
Reviewed on 28 Jul. 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Santa Cruz
Cine Center
You can make plans for a show at Cine Center on your trip to Santa Cruz. While in the area, you can find time to visit its shops.
What to do in Santa Cruz

Guided tour of the Che Guevara Museum in Vallegrande
AU$29
per adult

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
AU$129
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.