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Our top choices for Santa Cruz Tlaxcala hotels

Elite Suite (Camaldoni)
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
3.5 star property
Santeagueda
9.4 out of 10, Exceptional, (370)
"The rooms were very nice, though the area is made to look like Italian towns tbe rooms were large and confortable highly recommend a stay at this hotel "
United States
Jose
The price is AU$256
includes taxes & fees
29 Jan - 30 Jan 2026
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
Outdoor pool
Marriott Puebla Hotel Meson del Angel

Marriott Puebla Hotel Meson del Angel

Marriott Puebla Hotel Meson del Angel
4.5 star property
Puebla
8.8 out of 10, Excellent, (979)
"Great Hotel !!"
United States
JUAN
The price is AU$140
includes taxes & fees
8 Jan - 9 Jan 2026
Marriott Puebla Hotel Meson del Angel
Lunch and dinner served, international cuisine
Ramada Encore Puebla Mexico

Ramada Encore Puebla Mexico

Ramada Encore Puebla Mexico
4.0 star property
Coronango
9.2 out of 10, Wonderful, (1000)
"Todo excelente"
Mexico
Axel
The price is AU$119
includes taxes & fees
8 Jan - 9 Jan 2026
Ramada Encore Puebla Mexico
Meeting facility
Holiday Inn Tlaxcala by IHG

Holiday Inn Tlaxcala by IHG

Holiday Inn Tlaxcala by IHG
3.5 star property
Yauhquemehcan
9.6 out of 10, Exceptional, (244)
"Todo excelente"
Mexico
carlos
The price is AU$156
includes taxes & fees
17 Jan - 18 Jan 2026
Holiday Inn Tlaxcala by IHG
Terrace/patio
Mesón Santa Rosa

Mesón Santa Rosa

Mesón Santa Rosa
3.0 star property
Tlaxcala
9.4 out of 10, Exceptional, (54)
"Excellent location, quiet, wonderful service and great price. Would definitely stay there again. "
United States
Mario
Mesón Santa Rosa
Comfort Room, Private Bathroom
Sendero de San Francisco

Sendero de San Francisco

Sendero de San Francisco
2.0 star property
Apizaco
10.0 out of 10, Exceptional, (2)
"Los cuartos son pequeños, lo que hace falta en el baño es alguna cortina o cancel ya que el agua se sale mucho y el baño se moja todo, lo que si hay que tener precaución es con las camas ya que están elevadas y yo no alcace bien y por poco y me caigo. Lo que si que los dueños o encargados del lugar son unas personas muy amables y atentas, me agradaron mucho y el café le encanto a mi mamá. Si recomiendo el lugar."
Mexico
anatoscu
The price is AU$68
includes taxes & fees
1 Jan - 2 Jan 2026
Sendero de San Francisco
Bar (on property)
Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala
3.5 star property
Tlaxcala
9.0 out of 10, Wonderful, (378)
"Good Hotel."
United States
Dallas
The price is AU$116
includes taxes & fees
10 Jan - 11 Jan 2026
Hotel San Francisco Tlaxcala
Buffet breakfast on weekends (MXN 320 per person)
Hacienda Soltepec Suites Campo de Golf

Hacienda Soltepec Suites Campo de Golf

Hacienda Soltepec Suites Campo de Golf
3.0 star property
Huamantla
9.0 out of 10, Wonderful, (228)
"X"
Mexico
ERICK FLORES
The price is AU$198
includes taxes & fees
11 Jan - 12 Jan 2026
Hacienda Soltepec Suites Campo de Golf
Rooftop terrace
Gran Hotel de Puebla by HNF

Gran Hotel de Puebla by HNF

Gran Hotel de Puebla by HNF
4.0 star property
Puebla
9.4 out of 10, Exceptional, (477)
"Everything was excellent!"
United States
Eri
The price is AU$107
includes taxes & fees
7 Jan - 8 Jan 2026
Gran Hotel de Puebla by HNF
Interior entrance
Casa Tlaxcalli by Beddo Hoteles

Casa Tlaxcalli by Beddo Hoteles

Casa Tlaxcalli by Beddo Hoteles
2.0 star property
Tlaxcala
9.0 out of 10, Wonderful, (56)
"Great stay, rooms are spotless and very friendly and helpful staff. Would be great if they could add a mini-bar to the room and a coffee maker but restaurants are quite close so it wasn’t an issue."
United Kingdom
Mercedes
Casa Tlaxcalli by Beddo Hoteles
Reception
Hotel del Angel, Apizaco

Hotel del Angel, Apizaco

Hotel del Angel, Apizaco
3.5 star property
San Martin de Porres
8.8 out of 10, Excellent, (278)
"Room wa a lean and they would come in everyday to make the beds and restock with water bottles. The staff was super nice and helpful and the staff in the restaurant were amazing super attentive and nice"
United States
Anakaren
Hotel del Angel, Apizaco
Garden
Hotel Quinta San Clemente

Hotel Quinta San Clemente

Hotel Quinta San Clemente
3.0 star property
Tlaxcala
7.6 out of 10, Good, (76)
"Todo muy bien , todo el personal muy amables y buen servicio. La cama muy cómoda y limpia la habitación. El desayuno muy rico y suficiente."
Mexico
Durdane
The price is AU$80
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Quinta San Clemente
Outdoor pool
Staybridge Suites Puebla by IHG

Staybridge Suites Puebla by IHG

Staybridge Suites Puebla by IHG
3.0 star property
Puebla
9.6 out of 10, Exceptional, (559)
"K"
United States
alejandro Rosario
The price is AU$140
includes taxes & fees
10 Jan - 11 Jan 2026
Staybridge Suites Puebla by IHG
Indoor pool
Holiday Inn Puebla Finsa by IHG

Holiday Inn Puebla Finsa by IHG

Holiday Inn Puebla Finsa by IHG
4.0 star property
Puebla
9.2 out of 10, Wonderful, (804)
"Staff was very friendly, room was spacious "
Canada
Arturo
The price is AU$108
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Puebla Finsa by IHG
Comfort Loft
Pietro Santo

Pietro Santo

Pietro Santo
2.0 star property
Santeagueda
9.4 out of 10, Exceptional, (141)
"Very nice hotel. And excellent service. Valquirico is a wonderful destination for dining shopping and walking around. The hotel is located right in the center. "
United States
Carlos
Pietro Santo
Terrace/patio
La Bella Toscana Centro

La Bella Toscana Centro

La Bella Toscana Centro
2.0 star property
Santeagueda
9.8 out of 10, Exceptional, (100)
"Excellent place to visit."
United States
Enrique
La Bella Toscana Centro
Indoor pool, open 7:00 AM to 9:00 PM, pool loungers
Hotel Senorial Tlaxcala

Hotel Senorial Tlaxcala

Hotel Senorial Tlaxcala
3.5 star property
Tlaxcala
8.8 out of 10, Excellent, (153)
"Hotel overall was clean, safe and quiet. Ample amount of room. Staff was nice and hospitable. Definitely recommend. "
United States
Janie
Hotel Senorial Tlaxcala
Terrace/patio
Hotel Tlaxcala

Hotel Tlaxcala

Hotel Tlaxcala
3.5 star property
Tlaxcala
8.2 out of 10, Very good, (102)
"👍"
Mexico
Gerardo
The price is AU$56
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Tlaxcala
Minibar, in-room safe, desk, soundproofing
NH Puebla Finsa

NH Puebla Finsa

NH Puebla Finsa
3.5 star property
Puebla
9.2 out of 10, Wonderful, (380)
"good place to stay on a budget."
Mexico
Josué Elías Pérez
The price is AU$98
includes taxes & fees
2 Jan - 3 Jan 2026
NH Puebla Finsa
Exterior
Molino de los Reyes

Molino de los Reyes

Molino de los Reyes
3.5 star property
Totolac
8.8 out of 10, Excellent, (9)
"Me gustó la habitación, el ambiente generado y la comodidad, con algunos detalles. la habitación no se obscurece completamente y y un escalón peligroso. El personal al muy atento y servicial."
Mexico
JESUS HERIBERTO
Molino de los Reyes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Tlaxcala Hotel Reviews

Recent Reviews in Santa Cruz Tlaxcala

Fiesta Inn Parque Puebla

Fiesta Inn Parque Puebla

10/10 Excellent
"The hotel ia very nice, clean, practical. Rooms are comfortable. Staff is very nice."
Miguel Angel 1-night trip
Posted 7 days ago
Fiesta Inn Parque Puebla

More cheap accommodation in Santa Cruz Tlaxcala

Hotel Royal Puebla

Hotel Royal Puebla

Atilac San Felipe Hueyotlipan Puebla PUE
The price is AU$49 per night from 8 Jan to 9 Jan
AU$49
8 Jan - 9 Jan 2026
includes taxes & fees
7.4/10 Good! (124 reviews)

Frequently asked questions

Where is the best place for a stay in Santa Cruz Tlaxcala?
Ramada Encore Puebla Mexico, located 17.6 mi (28.3 km) from the heart of Santa Cruz Tlaxcala, is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Gran Hotel de Puebla by HNF and NH Puebla Finsa. See all available top hotels, or vacation rentals in Santa Cruz Tlaxcala.
What are some of the best holiday rentals that Santa Cruz Tlaxcala has to offer?
Luxurious Casa Residencial Privada: This highly rated holiday home rental in Santa Cruz Tlaxcala offers a balcony and laundry facilities to help you feel comfortable in your new surroundings. It has 3 bedrooms, in addition to a kitchen with a microwave and kitchenware. See all vacation rentals in Santa Cruz Tlaxcala.
If I need to cancel my hotel reservation in Santa Cruz Tlaxcala, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz Tlaxcala.
How is it staying in Santa Cruz Tlaxcala?
Visitors can enjoy all that Santa Cruz Tlaxcala has to offer, including its parks. There are 214 hotels and other accommodation options in the surrounding area. Find out more about Santa Cruz Tlaxcala.
What is there to see in Santa Cruz Tlaxcala?
Places to visit in the wider area include Basilica of Ocotlan, Xicotencatl Theater and University Cultural Center. You'll also find La Malinche National Park and Xicotencatl National Park in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz Tlaxcala guide.
What's the seasonal weather like in Santa Cruz Tlaxcala?
The hottest months are usually April and May, with an average temperature of 16°C, while the coldest months are January and December, with an average of 12°C. The rainiest months in Santa Cruz Tlaxcala are August, September, July and June, with each month seeing an average of 249 mm of rainfall.