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Check prices for these dates

This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Santa Cruz hotels

A modern hotel lobby with a reception desk, seating area, and large windows offering a city view.

1. Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales
3.5 star property
Nogales
8.4 out of 10, Very good, (1,002 reviews)
"Rooms were great nice and clean … staff were very nice and helpful.."
United States
David
The price is AU$180
includes taxes & fees
20 Nov - 21 Nov
Fairfield Inn & Suites by Marriott Nogales
A cozy living room with a sofa, ottoman, and round coffee table, surrounded by potted plants and a mounted deer head.

2. Hotel Fray Marcos

Hotel Fray Marcos
3.5 star property
Centro
7.8 out of 10, Good, (487 reviews)
"Friend and helpfulk valet staff!"
United States
Daniel
The price is AU$148
includes taxes & fees
11 Nov - 12 Nov
Hotel Fray Marcos
A modern lobby with a reception desk, seating area, and large windows offering a view of the outside.

3. City Express by Marriott Nogales

City Express by Marriott Nogales
3.0 star property
Nueva Nogales
8.8 out of 10, Excellent, (1,006 reviews)
"Hotel in ok condition"
United States
Julio
The price is AU$91
includes taxes & fees
27 Nov - 28 Nov
City Express by Marriott Nogales
A pathway flanked by neatly trimmed hedges and palm trees, leading to a building with a modern design and a red and blue sign.

4. Fiesta Inn Nogales

Fiesta Inn Nogales
3.5 star property
Nueva Nogales
8.2 out of 10, Very good, (1,000 reviews)
"Thanks exelente place"
United States
Mario
The price is AU$158
includes taxes & fees
12 Nov - 13 Nov
Fiesta Inn Nogales
A multi-story building with balconies, a brick column, and a table with chairs.

5. Hotel Marques De Cima

Hotel Marques De Cima
2.5 star property
Nogales
8.6 out of 10, Excellent, (928 reviews)
"Amazing stay! Will definitely be back."
United States
Cristal
The price is AU$149
includes taxes & fees
12 Nov - 13 Nov
Hotel Marques De Cima
A multi-story residential building with balconies, a covered walkway, and a green hedge.

6. Motel San Luis de Nogales

Motel San Luis de Nogales
3.0 star property
Centro
9.4 out of 10, Exceptional, (3 reviews)
"I was satisfied with my stay"
United States
Tracy
The price is AU$86
includes taxes & fees
12 Nov - 13 Nov
Motel San Luis de Nogales
A bedroom with two beds, a wardrobe, and a door.

7. Hotel Pedregal

Hotel Pedregal
2.0 star property
Colinas del Yaqui
8.4 out of 10, Very good, (65 reviews)
"My daughter and I always stay here and it's always point in with staff, very courteous, and accommodating with us. "
United States
Idaliee
The price is AU$134
includes taxes & fees
11 Nov - 12 Nov
Hotel Pedregal
A modern meeting room with a round table, grey chairs, a sofa, and a ceiling fan.

8. Departamento Kennedy Nogales

Departamento Kennedy Nogales
2.0 star property
Kennedy
The price is AU$167
includes taxes & fees
11 Nov - 12 Nov
Departamento Kennedy Nogales
A reception area with a counter, pendant lights, a plant, and a glass wall.

9. City Express by Marriott Cananea

City Express by Marriott Cananea
3.0 star property
Cananea
9.2 out of 10, Wonderful, (413 reviews)
"Clean room and very friendly staff."
United States
Erika
The price is AU$115
includes taxes & fees
22 Nov - 23 Nov
City Express by Marriott Cananea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Recent Reviews in Santa Cruz

Hotel Fray Marcos

Hotel Fray Marcos

10/10 Excellent
"It’s clean, staff were helpful"
Frank 1-night trip
Posted 7 hours ago
Hotel Fray Marcos

More cheap accommodation in Santa Cruz

Hotel Pedregal

Hotel Pedregal

Av. del Yaqui Colinas del Yaqui Nogales Son.
The price is AU$134 per night from 11 Nov to 12 Nov
AU$134
11 Nov - 12 Nov
includes taxes & fees

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz, Sonora, is the town centre, particularly around the main square, Plaza Zaragoza.

This area is the heart of Santa Cruz, offering a convenient base for exploring. You'll find many of the town's key landmarks, including the historic Templo de Nuestra Señora de Guadalupe, within easy walking distance. The streets here are generally well-maintained and offer a pleasant stroll amongst local shops and eateries.

Couples looking for a relaxed and authentic experience will find the town centre ideal. It provides opportunities to enjoy local cuisine, browse artisan crafts, and simply soak in the local way of life without needing to travel far. The evenings around Plaza Zaragoza often feature local gatherings, adding to the pleasant atmosphere.
When is the best time to go to Santa Cruz?
The best time to visit Santa Cruz, Sonora, Mexico is during the cooler, drier months from November to April.

During this period, the weather is pleasantly warm with average temperatures ranging from 20°C to 28°C, and there's very little rainfall. This makes it ideal for exploring the outdoors, whether you're interested in hiking the Sierra Azul mountains or enjoying the local markets without the intense heat of summer.

Couples looking for a relaxed getaway will appreciate the comfortable climate for leisurely strolls through the town's historic centre, perhaps visiting the Mission de Santa Cruz. The evenings are mild, superb for dining al fresco.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How can I save on a hotel booking in Santa Cruz with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Santa Cruz hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Santa Cruz?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from AU$86 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.