A large brick church with two bell towers and palm trees in front.

Search Santa Cruz de la Sierra hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
31 Aug - 1 Sept
Tomorrow
1 Sept - 2 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Filter by

Property class

Guest rating

Our top choices for Santa Cruz de la Sierra hotels

1. Finca El Azahar

Finca El Azahar
Trujillo
Canada
Alex
AU$230
includes taxes & fees
1 Oct - 2 Oct
Finca El Azahar

2. Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
Madronera
United States
Jose Luis
AU$105
includes taxes & fees
11 Sept - 12 Sept
Hospedium Hotel Soterraña

3. Parador de Trujillo

Parador de Trujillo
Trujillo
United States
wilton
AU$155
includes taxes & fees
2 Sept - 3 Sept
Parador de Trujillo

4. Hotel Izan Trujillo

Hotel Izan Trujillo
Trujillo
Spain
Monica
AU$146
includes taxes & fees
1 Sept - 2 Sept
Hotel Izan Trujillo

5. Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
Trujillo
United States
Ana
AU$122
includes taxes & fees
30 Sept - 1 Oct
Eurostars Palacio Santa Marta

6. Hostal Hueso

Hostal Hueso
Trujillo
United States
ALFRED
AU$105
includes taxes & fees
1 Sept - 2 Sept
Hostal Hueso

7. Finca la Desa

Finca la Desa
Miajadas
New Zealand
Craig
AU$116
includes taxes & fees
1 Sept - 2 Sept
Finca la Desa

8. Hostal León

Hostal León
Trujillo
United Kingdom
Gareth
AU$89
includes taxes & fees
1 Sept - 2 Sept
Hostal León

9. Plaza Sandra

Plaza Sandra
Trujillo
United States
Ismael
AU$110
includes taxes & fees
8 Sept - 9 Sept
Plaza Sandra

10. Alojamientos Plaza Mayor

Alojamientos Plaza Mayor
Trujillo
United States
Adela
AU$46
includes taxes & fees
2 Sept - 3 Sept
Alojamientos Plaza Mayor

11. Hostal Ruralis Altozano

Hostal Ruralis Altozano
Montánchez
Spain
MARCO ANTONIO
AU$67
includes taxes & fees
20 Sept - 21 Sept
Hostal Ruralis Altozano

12. Hospedium Hotel Triana

Hospedium Hotel Triana
Miajadas
United Kingdom
tina
AU$126
includes taxes & fees
2 Sept - 3 Sept
Hospedium Hotel Triana
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santa Cruz de la Sierra

Venture to Palacio de la Conquista and Plaza Mayor—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra
A large brick church with two bell towers and palm trees in front.

Top Santa Cruz de la Sierra Hotel Reviews

Recent Reviews in Santa Cruz de la Sierra

Hotel Izan Trujillo

Hotel Izan Trujillo

10/10 Excellent
"Nice hotel with a secure room for cycles for those on tour like me. Nice rooms and good facilities. Restaurant is good but also great places to eat on the Plaza."
Mark 1-night trip
Posted 6 days ago
Hotel Izan Trujillo
Parador de Trujillo

Parador de Trujillo

10/10 Excellent
"We had half board abd the meal was fantastic. I had the selection of meats to start and my wife had a sort of tomato mousse. The olive oil was out of this world and my main course fillet was one of the best that I have ever had. We have been trying to find a reason to travel that way again and wish we had booked for 2 nights or more. It’s a lovely little town, with a beautiful square. A great place as a base to visit Caceres or Guadalupe. We will definitely return!"
Gary 1-night trip
Posted 13 days ago
Parador de Trujillo
Hospedium Hotel Soterraña

Hospedium Hotel Soterraña

10/10 Excellent
"The staff was friendly and helpful, the rooms clean. The food was also good. We liked the location, minutes away drive to Trujillo and a great stop if coming from a city like Sevilla heading to Madrid. We enjoyed our stay !"
Jose Luis 1-night trip
Posted 1 month ago
Hospedium Hotel Soterraña
Plaza Sandra

Plaza Sandra

10/10 Excellent
"Era un lugar limpio y acogedor, y había muchos sitios a los que se podía ir andando. El personal fue muy atento. Aparcar fue todo un reto, sobre todo cerca del mercado semanal. Pasamos una estancia muy agradable."
Alexandra 3-night trip
Posted 2 months ago
Plaza Sandra
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

10/10 Excellent
"We had a wonderful stay at Eurostars Palacio Santa Marta. The hotel is set inside a beautifully restored historic building just steps from Plaza Mayor, making it perfect for exploring Trujillo on foot. Our room was spacious, comfortable, and very quiet. Alba was warm, welcoming, and made everything easy. Overall, an excellent stay in a charming location — we’d happily return."
Ismael 1-night trip
Posted 3 months ago
Eurostars Palacio Santa Marta
El Majano Rural Cottage for 6 people

El Majano Rural Cottage for 6 people

10/10 Excellent
"Si al paraiso hubiera que renombrarlo, lo llamaria finca el majano.Este gema de lugar esta en un paraje increible rodeado de naturaleza y unas vistas que quitan la respiracion.La finca esta a unos 15 mins a pie del pueblo donde se pueden degustar excelentes jamones, hacer rutas de senderismo o visitar los pueblos colindantes. El jardin es una maravilla para relajarse para humanos y perritos.Antonio es un anfitrion excelente. Con su calurosa recepcion y atencion durante nuestra estancia, se aseguró que todo estuviera perfecto. No olvidar que hay gallinas y por tanto se puede disfrutar de huevos frescos todos los dias. Ademas de chimenea, barbacoa, pista de petanca (y bolas disponibles), piscina y prismaticos para observar las aves."
Jelle S. 7-night trip
Posted 4 months ago
El Majano Rural Cottage for 6 people
Finca la Desa

Finca la Desa

10/10 Excellent
"This is a diamond in the west country of Spain. Everything about this place was exceptional."
Craig 1-night trip
Posted 6 months ago
Finca la Desa
Hostal Hueso

Hostal Hueso

10/10 Excellent
"Excelent location, excelent staf"
ALFRED 1-night trip
Posted 1 year ago
Hostal Hueso

More cheap accommodation in Santa Cruz de la Sierra

Hostal León

Hostal León

Campillo 11 Trujillo Caceres
AU$89
1 Sept - 2 Sept
includes taxes & fees
7.6/10 Good! (55 reviews)
Hostal León
Hostal Hueso

Hostal Hueso

Calle Arquillo, 4 Trujillo Cáceres
AU$105
1 Sept - 2 Sept
includes taxes & fees
8.2/10 Very good! (26 reviews)
Hostal Hueso
Posada dos Orillas

Posada dos Orillas

Calle Cambrones N6-8 Trujillo
Get ratesPosada dos Orillas
HOTEL RURAL EL LABRIEGO BY VIVERE STAYS

HOTEL RURAL EL LABRIEGO BY VIVERE STAYS

C. Tiendas 7 Plasenzuela Cáceres
Get rates
9.2/10 Wonderful! (19 reviews)
HOTEL RURAL EL LABRIEGO BY VIVERE STAYS
Hostal San Miguel

Hostal San Miguel

Plaza San Miguel, 3 Trujillo Caceres
Get rates
8.4/10 Very good! (51 reviews)
Hostal San Miguel
Hostal - Restaurante Emilia

Hostal - Restaurante Emilia

PLAZA DEL CAMPILLO, 28 Trujillo CACERES
Get rates
9.2/10 Wonderful! (22 reviews)
Hostal - Restaurante Emilia

Frequently asked questions

What is the best area to stay in Santa Cruz De La Sierra?
The best area to stay in Santa Cruz De La Sierra is within the historic centre, particularly around the Plaza de España.This area is the heart of the village and is very walkable. It's characterised by traditional Extremaduran architecture, with narrow, winding streets that lead to the central square. The Plaza de España itself is a focal point, often featuring outdoor seating from local eateries and providing a pleasant spot to relax. You'll find the Church of Santiago Apóstol nearby, which is a significant landmark.For couples seeking a peaceful retreat, staying near the Plaza de España is ideal. It offers a charming setting for evening strolls and provides easy access to local restaurants and the village's main points of interest.
When is the best time to go to Santa Cruz De La Sierra?
The best time to visit Santa Cruz De La Sierra is during the spring (April to June) and autumn (September to October) months, when the weather is most pleasant for exploring.During these periods, you'll experience mild temperatures, typically ranging from 18°C to 25°C, making it ideal for walking around and enjoying the town's historic sites without the intense heat of summer. The countryside around Santa Cruz De La Sierra is also at its most picturesque, with blooming wildflowers in spring and rich autumnal colours. This provides a comfortable experience for couples looking to enjoy the scenery and local culture at a relaxed pace.Summer, particularly July and August, can be very hot, with temperatures often exceeding 30°C. While there are fewer crowds, sightseeing can be less comfortable.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz de la Sierra.
How can I save on a hotel booking in Santa Cruz de la Sierra with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Santa Cruz de la Sierra hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Santa Cruz de la Sierra?
Prices for hotels in Santa Cruz de la Sierra often vary, but you can find a great deal from AU$46 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia