A large brick church with two bell towers and palm trees in front.

Santa Cruz de la Sierra Holidays from AU$3,648

Book a Hotel + Flight or Car together to unlock savings

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    Save up to AU$2,500 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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The Latest Santa Cruz de la Sierra holiday deals

Price found within the past 48 hours. Click for updated prices.
  • 26 Dec - 2 Jan

    Novotel Madrid Center + Flight

    Salamanca
    6 nights
    4.0 star property
    9.2/10 - Wonderful (1,352 reviews)
    Return • Brisbane (BNE) - Madrid (MAD)
    BNE - MAD • 1 stop MAD - BNE • 1 stop
    AU$4,249
    AU$3,648
    per traveller
    found 1 day ago
    Novotel Madrid Center
  • 26 Dec - 2 Jan

    Hotel Regina + Flight

    Madrid Centro
    6 nights
    4.0 star property
    9.8/10 - Exceptional (2,450 reviews)
    Return • Brisbane (BNE) - Madrid (MAD)
    BNE - MAD • 1 stop MAD - BNE • 1 stop
    AU$5,485
    AU$4,329
    per traveller
    found 1 day ago
    Hotel Regina
  • 26 Dec - 2 Jan

    The Social Hub Madrid 4 star + Flight

    Austrias
    6 nights
    4.0 star property
    9.0/10 - Wonderful (334 reviews)
    "The hotel was by far the best stay in all our trip, the restaurant in the hotel has a very diverse menu which was delicious and affordable. The location was right across the street from the Royal Palace and was super convenient to all of the rest of Madrid. It has a bus stop right in from and is a couple streets away from a train station which means you can reach all of Madrid in a variety of ways. The room was very modern and the amenities were very comfortable, on the last day I was able to..."
    Reviewed November 13, 2026
    Return • Brisbane (BNE) - Madrid (MAD)
    BNE - MAD • 1 stop MAD - BNE • 1 stop
    AU$4,441
    AU$3,757
    per traveller
    found 1 day ago
    The Social Hub Madrid 4 star
  • 26 Dec - 2 Jan

    SLEEP’N Atocha – B Corp Certified + Flight

    Madrid Centro
    6 nights
    2.0 star property
    9.4/10 - Exceptional (1,955 reviews)
    "The room is very small but clean and has all that is required."
    Reviewed November 13, 2026
    Return • Brisbane (BNE) - Madrid (MAD)
    BNE - MAD • 1 stop MAD - BNE • 1 stop
    AU$4,332
    AU$3,714
    per traveller
    found 1 day ago
    SLEEP’N Atocha – B Corp Certified
  • 26 Dec - 2 Jan

    Hotel Riu Plaza España + Flight

    Madrid Centro
    6 nights
    4.0 star property
    9.4/10 - Exceptional (5,314 reviews)
    Return • Brisbane (BNE) - Madrid (MAD)
    BNE - MAD • 1 stop MAD - BNE • 1 stop
    AU$4,805
    AU$4,183
    per traveller
    found 1 day ago
    Hotel Riu Plaza España

Santa Cruz de la Sierra Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Santa Cruz de la Sierra holiday package cost?

You can snap up a holiday package to this top destination from AU$3,648 on Expedia. However, how much your holiday to Santa Cruz de la Sierra costs will depend on factors like your hotel choice, season and length of stay.

What are the cheapest months to go to Santa Cruz de la Sierra?

Plan your getaway for the low season and you're likely to get cheap Santa Cruz de la Sierra holiday packages. Bear in mind that public holidays and major events and festivals can have an impact on prices, so do some research before booking.

How many days is enough for Santa Cruz de la Sierra?

Usually, a handful of days is enough to see the main attractions during your Santa Cruz de la Sierra holiday. But if you want to have some time to kick back or take day trips, think about extending your itinerary.

How to find the best Santa Cruz de la Sierra package deals?

Use Expedia's filters to find some of the best Santa Cruz de la Sierra package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or search for Santa Cruz de la Sierra package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your holiday package as soon as possible.

Is it cheaper to book a Santa Cruz de la Sierra holiday as a package?

An Expedia holiday package could land you great savings when compared to arranging hotels and flights separately. Better still, you can customise your Santa Cruz de la Sierra getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.

When to book a holiday package to Santa Cruz de la Sierra?

If you're planning a spontaneous Santa Cruz de la Sierra getaway, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can find incredible deals on your hotels and flights by booking ahead.

How to plan a trip to Santa Cruz de la Sierra?

  1. Choose the ideal time to travel: Your schedule, favourite season and the type of weather you like can all influence your decision on when to travel to Santa Cruz de la Sierra.
  2. Set your budget: Factor in expenses like flights, meals and transportation when working out how much to save for your trip to Santa Cruz de la Sierra. Then, select a hotel that matches your budget, whether that's a low-cost option or a more luxurious retreat.
  3. Decide your trip length: Consider how much time you want to spend exploring Santa Cruz de la Sierra. Plan your days so you can get to all the activities and attractions you're interested in at a comfortable pace.
  4. Bundle your bookings: With your travel dates in order, you can combine your flights, hotels, car rental and more into a personalised Santa Cruz de la Sierra holiday package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.