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Santa Ana Hotels, Cusco

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Our top choices for Santa Ana hotels

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1008)
"great hotel"
United States
Rodolfo
The price is AU$170
8 Jan - 9 Jan 2026
Hilton Garden Inn Cusco

Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (12)
"A pleasant place to visit Cuzco"
France
Michel
Centro by Casa Andina Cusco Saphi

Hotel Cusco Pacha Inti

Hotel Cusco Pacha Inti
3.0 star property
Santa Ana
6.0 out of 10, (1)
"El hotel cumple con sus funciones, sin embargo es complicado el tema de la regadera, considero es un punto que pueden mejorar. El hotel no está alejado del centro pero está en una zona no tan cómoda de llegar, ni siquiera los autos tienen accedió tan fácil. El personal es muy atento y amable, sin embargo tuve que pagar dos veces la reservación porque a ellos "no se les reflejaba" siendo que ellos mismos confirmaron que tienen problemas con expedis y Booking y a pesar de que les mostré en mi...
Mexico
CR
The price is AU$44
23 Dec - 24 Dec
Hotel Cusco Pacha Inti

Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (499)
"Great place ! "
United States
Roger
Tierra Viva Cusco Saphi

ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
The price is AU$75
20 Dec - 21 Dec
ZEVEN HOUSE - CUSCO APARTMENT

Munay Cusco

Munay Cusco
2.0 star property
Santa Ana
The price is AU$26
25 Dec - 26 Dec
Munay Cusco

Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana
3.0 star property
Santa Ana
The price is AU$48
25 Dec - 26 Dec
Hotel El Mirador de Santa Ana

Anata Hostel

Anata Hostel
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (22)
"Great location, staff incredible!"
Canada
christiane
The price is AU$33
11 Jan - 12 Jan 2026
Anata Hostel

Munay Ñusta Cusco

Munay Ñusta Cusco
3.0 star property
Santa Ana
9.6 out of 10, Exceptional, (4)
"Very nice property"
United States
Arthur
The price is AU$74
17 Dec - 18 Dec
Munay Ñusta Cusco

Casa Karmenka

Casa Karmenka
2.5 star property
Santa Ana
Casa Karmenka

Hotel Mamasara

Hotel Mamasara
3.0 star property
Santa Ana
8.4 out of 10, Very good, (18)
"It was nice"
United States
Alexander
Hotel Mamasara

Santa Ana Departamentos

Santa Ana Departamentos
2.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Grand appartement à 10 min à pied de la place des Armes. Il y a également un bus qui s'arrête devant le portail. Nous sommes toujours descendus à pied et remontés en navette. Eau chaude, appartement un peu froid mais pas insurmontable. Accueil très sympathique et agréable de la part des propriétaires, n'hésitez pas à leur demander conseils ou de l'aide ils feront tout pour vous aider. Nous avons passé un excellent séjour grâce à eux."
France
Mélissa
Santa Ana Departamentos

Tucan Hostel

Tucan Hostel
2.0 star property
Santa Ana
8.4 out of 10, Very good, (14)
"We found this hostel to be a very special place, filled with wonderfully helpful and pleasant folks. We would highly recommend a stay."
United States
Anonymous traveller
The price is AU$47
8 Jan - 9 Jan 2026
Tucan Hostel

HOSTAL LA RASA

HOSTAL LA RASA
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (2)
"Accueil très agréable !"
France
Lia
The price is AU$30
20 Dec - 21 Dec
HOSTAL LA RASA

LP Los Portales Hotel Cusco

LP Los Portales Hotel Cusco
3.5 star property
Cusco Historic Center, 1.4 km from Santa Ana
9.4 out of 10, Exceptional, (778)
"Located in in the historic district/staff more than helpful/great restaurant/clean room/I recommend without reservation"
United States
Herman Glenn
The price is AU$119
19 Dec - 20 Dec
LP Los Portales Hotel Cusco

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco
4.0 star property
Cusco Historic Center, 0.5 km from Santa Ana
9.4 out of 10, Exceptional, (1104)
"Staff is absolutely wonderful! Excellent breakfast too"
Canada
Patrick
The price is AU$183
15 Jan - 16 Jan 2026
Wyndham Costa del Sol Cusco

Aranwa Sacred Valley

Aranwa Sacred Valley
4.0 star property
21.8 km from Santa Ana
9.4 out of 10, Exceptional, (136)
"The best place with the more considerate and kind staff"
United States
Laura
The price is AU$560
1 Jan - 2 Jan 2026
Aranwa Sacred Valley

Tierra Viva Cusco Centro

Tierra Viva Cusco Centro
3.0 star property
Cusco Historic Center, 0.8 km from Santa Ana
9.4 out of 10, Exceptional, (1002)
"Lovely staff, charming room and great location."
United States
Shelley
Tierra Viva Cusco Centro

Sonesta Hotel Cusco

Sonesta Hotel Cusco
4.0 star property
Cusco Historic Center, 1.7 km from Santa Ana
9.6 out of 10, Exceptional, (1006)
"Nice rooms and helpful staff"
Canada
Laura
The price is AU$222
17 Dec - 18 Dec
Sonesta Hotel Cusco

Yawar Inka Hotel

Yawar Inka Hotel
3.5 star property
Cusco Historic Center, 1.7 km from Santa Ana
9.2 out of 10, Wonderful, (334)
"Everything was spotless and the staff were very helpful. The breakfast was very good"
United States
Fany Judith
The price is AU$112
1 Jan - 2 Jan 2026
Yawar Inka Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Cusco Historic Center

Cusco Historic Center is known for its popular shops, and with sights like Santa Catalina Convent and Coricancha, you won't get bored spending a day wandering around this part of Cusco.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Plaza de las Nazarenas and Plaza Sán Cristobal.

Santiago

If you're looking for some top things to see and do in Santiago and surrounding area, you can visit Ttio Market and Santiago Plaza.

Santa Monica

While Santa Monica may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Real Plaza Cusco and Ttio Market.

Top Santa Ana Hotel Reviews

Frequently asked questions

What is Santa Ana like?
Travellers to Cusco's Santa Ana neighbourhood will be sure to enjoy a stay here.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Hilton Garden Inn Cusco is the highest ranked property in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant. Other favourite options in the area include Tierra Viva Cusco Saphi and Hotel Mamasara.
How many hotels should I expect to find in the Santa Ana area?
If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 41 Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view top deals in Santa Ana.
What can I see and do in this Cusco neighbourhood?
A few places to visit in the area around Santa Ana include Museo Irq'i Yachay, Museo de Plantas Sagradas Magicas y Medicinales and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.