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Luxury Hotels & Resorts in Santa Ana from AU$26

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Check availability on Santa Ana Luxury Hotels

Our top choices for Santa Ana luxury hotels

Lobby sitting area
Palacio Manco Capac by Ananay Hotels

Palacio Manco Capac by Ananay Hotels

Palacio Manco Capac by Ananay Hotels
4.5 star property
Cusco Historic Center
9.6 out of 10, Exceptional, (325)
"Beautiful rooms and grounds. Staff are incredibly friendly and helpful. Breakfast is fantastic. "
United Kingdom
Ryan
The price is AU$159
17 Dec - 18 Dec
Palacio Manco Capac by Ananay Hotels
View from room
JW Marriott El Convento Cusco

JW Marriott El Convento Cusco

JW Marriott El Convento Cusco
5.0 star property
Cusco Historic Center
9.6 out of 10, Exceptional, (1000)
"We really liked the breakfast and the staffs were very helpful and friendly "
United States
Min
The price is AU$478
10 Jan - 11 Jan 2026
JW Marriott El Convento Cusco
Free daily buffet breakfast
Sonesta Hotel Cusco

Sonesta Hotel Cusco

Sonesta Hotel Cusco
4.0 star property
Cusco Historic Center
9.6 out of 10, Exceptional, (1006)
"Nice rooms and helpful staff"
Canada
Laura
The price is AU$222
17 Dec - 18 Dec
Sonesta Hotel Cusco
Interior
Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco
4.0 star property
Cusco Historic Center
9.4 out of 10, Exceptional, (1104)
"Staff is absolutely wonderful! Excellent breakfast too"
Canada
Patrick
The price is AU$182
15 Jan - 16 Jan 2026
Wyndham Costa del Sol Cusco
Breakfast, lunch and dinner served
Casa Andina Premium Cusco

Casa Andina Premium Cusco

Casa Andina Premium Cusco
4.0 star property
Cusco Historic Center
9.2 out of 10, Wonderful, (1001)
"The hotel was excellent, great staff, great breakfast, clean and Central"
United States
Lenda
The price is AU$207
16 Dec - 17 Dec
Casa Andina Premium Cusco
Junior Suite, 1 King Bed
Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott
5.0 star property
Cusco Historic Center
9.6 out of 10, Exceptional, (972)
"Great hotel. Clean room, amenities and very attentive staff. "
United States
Pablo
The price is AU$564
4 Jan - 5 Jan 2026
Palacio del Inka, A Luxury Collection Hotel by Marriott
LCD TV
Novotel Cusco

Novotel Cusco

Novotel Cusco
4.0 star property
Cusco Historic Center
9.4 out of 10, Exceptional, (1001)
"Amazing place to stay! "
United States
Giovanna
The price is AU$212
23 Dec - 24 Dec
Novotel Cusco
Breakfast, lunch, dinner served; Peruvian cuisine
Antigua Casona San Blas

Antigua Casona San Blas

Antigua Casona San Blas
4.0 star property
Cusco Historic Center
10.0 out of 10, Exceptional, (1006)
"Amazing staff, property, restaurant and location. 100% recommend this hotel"
United States
Cameron
The price is AU$263
5 Jan - 6 Jan 2026
Antigua Casona San Blas
Presidential Suite, 1 King Bed, City View, Tower
Tocuyeros Boutique Hotel

Tocuyeros Boutique Hotel

Tocuyeros Boutique Hotel
4.0 star property
Cusco Historic Center
9.8 out of 10, Exceptional, (386)
"Great little hotel, incredible view of the city, friendly and helpful staff. "
United States
Brian
The price is AU$244
16 Dec - 17 Dec
Tocuyeros Boutique Hotel
Reception
Hotel Taypikala Cusco

Hotel Taypikala Cusco

Hotel Taypikala Cusco
4.0 star property
Cusco Historic Center
9.0 out of 10, Wonderful, (816)
"Clean room and nice room. The hotel is beautiful with nice staff. Great choice of staying in Cusco, super close to Plaza de Armas. "
United States
Giancarlo
The price is AU$139
16 Dec - 17 Dec
Hotel Taypikala Cusco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Ana Hotel Reviews

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco

10/10 Excellent
"We love the colonial style of the rooms and of the courtyard absolutely beautiful! The staff were extremely friendly and helpful. The location is ideal for walking around the plaza de Armas area."
James 2-night trip
Posted 1 day ago
Wyndham Costa del Sol Cusco

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Santa Ana?
Use Expedia to help you arrange a flight to Cusco (CUZ-Alejandro Velasco Astete Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want a posh hotel with a spa, an indoor pool or luxury bedding, Expedia can help you find the best luxury hotel experience that Santa Ana offers.
What's there to see and do in Santa Ana?
Enjoy all that Santa Ana has to offer when you visit Museo de Plantas Sagradas Magicas y Medicinales, Plaza El Regocijo and San Pedro Market. If you have some spare time during your trip, you might want to check out Plaza de Armas and Inca Museum.

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