Sant' Ambrogio Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AU$2,500 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Sant Ambrogio Holiday

Make travel planning simple by locking in a holiday package to Sant Ambrogio. We'll take care of the finer points, so you can concentrate on discovering everything this neighbourhood can offer. Your trip to Sant Ambrogio wouldn't be complete without seeing leading attractions nearby such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia will help turn your dream Sant Ambrogio holiday into reality, whatever your budget or travel plans.

Our guide on where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Our pick of the best Sant' Ambrogio Hotel Deals

Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
The price is AU$598 per night from 30 July to 31 July
AU$598
30 July - 31 July
includes taxes & fees
9.4/10 Exceptional! (457 reviews)
"The property was located off the beaten path, across from a lovely park, which made it very quiet. Our room was HUGE and VERY comfortable! The staff was lovely and extremely helpful with cabs, directions, reservations, etc. etc. I would definitely stay here again, and look forward to returning!"

Reviewed on 22 June 2026

Hotel Regency
Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
The price is AU$136 per night from 18 Aug to 19 Aug
AU$136
18 Aug - 19 Aug
includes taxes & fees
8.2/10 Very good! (448 reviews)
"This was a nightmare. When we arrived, we were told to leave our bags and taken to another area to complete the check-in. On returning, it appeared that my bag had been opened. When we were taken up to our room (no elevator), there was no AC, only three fans pushing hot heat-wave air around. The ..."

Reviewed on 19 July 2026

Hotel Bavaria
Hotel Cardinal Of Florence

Hotel Cardinal Of Florence

3 out of 5
Via Borgo Pinti 5 Florence FI
Fully refundableReserve now, pay when you stay
The price is AU$179 per night from 23 Aug to 24 Aug
AU$179
23 Aug - 24 Aug
includes taxes & fees
8.6/10 Excellent! (355 reviews)
"The room was clean, staff was fantastic and the terrace had an amazing view of the city."

Reviewed on 11 July 2026

Hotel Cardinal Of Florence
See all 533 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

How much does a Sant Ambrogio holiday package cost?
Maybe less than you might think — from just , in fact! By combining hotels, flights and car rentals into your own custom-built travel package, your getaway to Sant Ambrogio is only clicks away.
How do I get a cheap travel package to Sant Ambrogio?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Sant Ambrogio holiday package makes it simple to arrange your perfect trip. With more than 550 airlines throughout the world to choose from, finding flights that suit your busy schedule won't be hard. On top of that, we've got over 1 000 000 hotel options globally to choose from. Talk about choice! No matter who you are, Expedia can show you the world.
Where should I stay in Sant Ambrogio?
A trip to Sant Ambrogio isn't complete until you've seen Cathedral of Santa Maria del Fiore and Ponte Vecchio. Book somewhere nearby for easy access to these popular attractions.
What are the top hotels in Sant Ambrogio?
Reserve a room at New Alfani. It's one of the area's most popular hotels. Another reputable option in Sant Ambrogio is Wine Apartments Florence Sangiovese.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are generally able to compare international airfares on Expedia within 12 months of departure. Booking at the last minute? With a bit of luck, it's still possible to purchase an affordable ticket only weeks before your flight.
What does an Expedia Sant Ambrogio travel package include?
Expedia has everything you need to organise your Sant Ambrogio trip, but what your package looks like is your call. Choose from any combination of flights, hotels and rental cars. Searching for some activities to keep you on the move? Once you've made your booking, you can add them too. No matter your budget or style, there's a package deal to match your needs.
What should I know before booking a Sant Ambrogio travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, combine your flights, hotels and rental cars and save a pretty penny. Whatever kind of holiday you're planning, you'll find a package that fits your budget.
Can I choose my airline with a Sant Ambrogio Expedia holiday package?
Yes, the choice is yours. We have access to over 550 airlines throughout the world, so you can tailor your Sant Ambrogio holiday according to your budget and needs.
If I'm not able to travel, can I cancel my Sant Ambrogio holiday package?
Don't worry if you're rethinking your Sant Ambrogio holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realise life can sometimes throw you a curveball, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Stay near popular Sant' Ambrogio attractions

Great Synagogue of Florence

9.0/10 (6 reviews)
Great Synagogue of Florence is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art galleries in this vibrant area.
See properties

Activities

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

AU$48
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

AU$31
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Michaelangelo's David

Accademia timed-entry Ticket with Instant Delivery & Priority Access

AU$68
per adult
94% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.