Luxury Hotels & Resorts in San Antonio from AU$29

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Check availability on San Antonio Luxury Hotels

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Best San Antonio Luxury Hotels

2 restaurants, breakfast served
La Mirage Garden Hotel And Spa

La Mirage Garden Hotel And Spa

4.0 star property
Cotacachi
9.8 out of 10, Exceptional, (59)
"Great hotel and outstanding service!"
United States
Liliana
La Mirage Garden Hotel And Spa
Superior King Suite
Medina del Lago

Medina del Lago

4.0 star property
Otavalo
9.4 out of 10, Exceptional, (52)
"Wonderfull "
United States
DIEGO
The price is AU$187
6 Jan - 7 Jan 2026
Medina del Lago
Front of property
PONDOWASI LODGE

PONDOWASI LODGE

4.0 star property
Angochagua
The price is AU$129
5 Jan - 6 Jan 2026
PONDOWASI LODGE
Front of property
Hotel Otavalo by Art Hotels Ecuador

Hotel Otavalo by Art Hotels Ecuador

4.5 star property
Otavalo
9.6 out of 10, Exceptional, (53)
"Beautiful property. Staff was lovely and service was excellent"
Canada
Catherine
Hotel Otavalo by Art Hotels Ecuador
Hot tub
Quinta Paolita

Quinta Paolita

4.0 star property
Tumbabiro
The price is AU$113
6 Jan - 7 Jan 2026
Quinta Paolita
Restaurant
Hacienda San Isidro Trails & Experiences

Hacienda San Isidro Trails & Experiences

4.0 star property
Cotacachi
2.0 out of 10, (1)
"Nunca estuvo abierta eso es una estafa como me pueden hacer un cargo a algo que no funciona "
Mexico
Catalina
The price is AU$155
8 Dec - 9 Dec
Hacienda San Isidro Trails & Experiences
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Antonio Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to San Antonio?
Use Expedia and let us help you arrange a flight to Quito (UIO-Mariscal Sucre Intl.) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a holiday, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that San Antonio offers.
When can I expect good weather in San Antonio?
Planning for the weather is an important factor for making your trip to San Antonio a success, especially when you're splurging. The hottest months are usually September and October, with an average temperature of 13°C, while the coldest months are August and July, with an average of 13°C. The rainiest months in San Antonio are April, November, March and February, with each month seeing an average of 280 mm of rainfall.
What's there to see and do in San Antonio?
Enjoy all that San Antonio has to offer and visit Yaguachi Military Barracks, Peguche Waterfall and El Lechero. If you have extra time while you're in the area, you might want to see Lago San Pablo and Plaza de Ponchos.