Photo by Levente Láng

San Antón Hotels, Santo Domingo

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Antón hotels

Gran Hotel Europa Santo Domingo, Trademark by Wyndham

Gran Hotel Europa Santo Domingo, Trademark by Wyndham
3.5 star property
San Antón
8.8 out of 10, Excellent, (911)
"Great location! "
United States
Valeska
The price is AU$167
includes taxes & fees
31 Dec - 1 Jan 2026
Gran Hotel Europa Santo Domingo, Trademark by Wyndham

Empyrean Art Deco

Empyrean Art Deco
3.0 star property
San Antón
9.2 out of 10, Wonderful, (84)
"Everything good!"
United States
milton
The price is AU$113
includes taxes & fees
7 Jan - 8 Jan 2026
Empyrean Art Deco

Casa de mabel

Casa de mabel
3.0 star property
San Antón
The price is AU$155
includes taxes & fees
5 Jan - 6 Jan 2026
Casa de mabel

Aparta Hotel Tiempo

Aparta Hotel Tiempo
2.0 star property
San Antón
The price is AU$44
includes taxes & fees
3 Jan - 4 Jan 2026
Aparta Hotel Tiempo

Diamonds Hotel Boutique

Diamonds Hotel Boutique
2.5 star property
San Antón
The price is AU$105
includes taxes & fees
31 Dec - 1 Jan 2026
Diamonds Hotel Boutique

Santo Domingo Bay Convention Resort & Casino

Santo Domingo Bay Convention Resort & Casino
4.0 star property
29.8 km from San Antón
The price is AU$400
includes taxes & fees
4 Jan - 5 Jan 2026
Santo Domingo Bay Convention Resort & Casino

Catalonia Santo Domingo

Catalonia Santo Domingo
5.0 star property
Ciudad Universitaria, 3.4 km from San Antón
8.8 out of 10, Excellent, (1749)
"Beautiful hotel."
United States
Mibolange
The price is AU$198
includes taxes & fees
30 Jan - 31 Jan 2026
Catalonia Santo Domingo

W&P Santo Domingo

W&P Santo Domingo
4.0 star property
Bella Vista, 5.9 km from San Antón
9.2 out of 10, Wonderful, (1178)
"The location, room, food and staff were fantastic! "
United States
Sandy
The price is AU$219
includes taxes & fees
19 Jan - 20 Jan 2026
W&P Santo Domingo

Hampton by Hilton Santo Domingo Airport

Hampton by Hilton Santo Domingo Airport
3.5 star property
23.5 km from San Antón
9.2 out of 10, Wonderful, (1002)
"Great hotel clean and close to airport"
United States
David
The price is AU$242
includes taxes & fees
30 Jan - 31 Jan 2026
Hampton by Hilton Santo Domingo Airport

CALYPSO BEACH HOTEL

CALYPSO BEACH HOTEL
3.0 star property
29.6 km from San Antón
7.4 out of 10, Good, (12)
"Excellent service and very affordable the staff very friendly!!!"
United States
Jaime
The price is AU$68
includes taxes & fees
4 Jan - 5 Jan 2026
CALYPSO BEACH HOTEL

Four Points by Sheraton Santo Domingo

Four Points by Sheraton Santo Domingo
4.0 star property
19.1 km from San Antón
8.2 out of 10, Very good, (199)
"Everything was really good for the price"
United States
Adrian
The price is AU$273
includes taxes & fees
30 Jan - 31 Jan 2026
Four Points by Sheraton Santo Domingo

Hotel Garant & Suites

Hotel Garant & Suites
3.0 star property
29.5 km from San Antón
8.6 out of 10, Excellent, (503)
"Staff very friendly and helpful "
United States
maria claribel
The price is AU$94
includes taxes & fees
31 Dec - 1 Jan 2026
Hotel Garant & Suites

Zile Hotel

Zile Hotel
3.0 star property
29.3 km from San Antón
The price is AU$83
includes taxes & fees
3 Jan - 4 Jan 2026
Zile Hotel

Hotel Casa Coco

Hotel Casa Coco
2.5 star property
29.4 km from San Antón
7.8 out of 10, Good, (177)
"Super "
Mexico
Francisco
The price is AU$74
includes taxes & fees
29 Jan - 30 Jan 2026
Hotel Casa Coco

El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel
5.0 star property
Bella Vista, 5.7 km from San Antón
9.2 out of 10, Wonderful, (1307)
"Great stay 100 % recommended "
United States
sauly
The price is AU$178
includes taxes & fees
30 Jan - 31 Jan 2026
El Embajador, a Royal Hideaway Hotel

Hotel Vicentina

Hotel Vicentina
3.0 star property
29.5 km from San Antón
8.6 out of 10, Excellent, (739)
"The staff Amazing & The Rooms As Well!!"
United States
diego
Hotel Vicentina

Radisson Hotel Santo Domingo

Radisson Hotel Santo Domingo
4.5 star property
Ensanche Naco, 4.4 km from San Antón
8.6 out of 10, Excellent, (1006)
"The best place"
United States
Sara
The price is AU$161
includes taxes & fees
18 Jan - 19 Jan 2026
Radisson Hotel Santo Domingo

Parco del caribe

Parco del caribe
3.0 star property
29.3 km from San Antón
9.0 out of 10, Wonderful, (244)
"The hospitality was great. My room was excellent and I enjoyed the people. They made me feel welcome and safe. There’s plenty of restaurants "
United States
Ronald
The price is AU$93
includes taxes & fees
8 Jan - 9 Jan 2026
Parco del caribe

Hotel Riazor

Hotel Riazor
3.5 star property
2.9 km from San Antón
9.2 out of 10, Wonderful, (1008)
"Good place to enjoy Santo Domingo "
United States
Gianny
Hotel Riazor

Santo Domingo Marriott Hotel Piantini - New Hotel

Santo Domingo Marriott Hotel Piantini - New Hotel
4.5 star property
Lope De Vega, 5.1 km from San Antón
9.4 out of 10, Exceptional, (255)
"I’ve stayed here a couple of times and continue to be impressed. The rooms are very clean, the location is convenient. "
United States
rogelio
The price is AU$233
includes taxes & fees
30 Jan - 31 Jan 2026
Santo Domingo Marriott Hotel Piantini - New Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in San Antón

Find the best San Antón areas for the activities you enjoy most.

Zona Colonial

Zona Colonial is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Calle El Conde or Santa Maria la Menor Cathedral.

Piantini

Unique features of Piantini include the shopping and restaurants. Make a stop by Blue Mall or Acropolis Center while you're exploring the area.

Downtown Santo Domingo

Consider exploring the abundant dining options in Downtown Santo Domingo. If sightseeing is on the list, Acropolis Center is a top attraction. Hop on the metro at Freddy Beras Goico Station or Juan Ulises Garcia Station to see more of the area.

Ciudad Colonial

If you're spending some time in Ciudad Colonial, Calle El Conde and Santa Maria la Menor Cathedral are top sights worth seeing.

Bella Vista

While there might not be top attractions in Bella Vista, you can explore the larger area and discover places like Acropolis Center and Bella Vista Mall.

Top San Antón Hotel Reviews

Frequently asked questions

What is San Antón like?
Travellers will be sure to find plenty to entertain them in Santo Domingo's San Antón neighbourhood. Make sure that you visit Fuerte de Santa Bárbara and Amber World Museum as part of your San Antón travel plans.
Where is the best place to stay in San Antón?
Based on Expedia customer reviews, Kimpton Las Mercedes by IHG is the highest ranked property in San Antón. This hotel is a short 10-minute walk from Malecon, and it offers a full-service spa and 3 restaurants. Other top choices in the neighbourhood include Empyrean Art Deco and Gran Hotel Europa Santo Domingo, Trademark by Wyndham.
How many hotels are there in San Antón?
Expedia has 21 hotels and other accommodation options in San Antón to choose from, making this an ideal home base for exploring the greater Santo Domingo area.
If I need to cancel my hotel reservation in San Antón, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer in San Antón.
What can I see and do in this Santo Domingo neighbourhood?
San Antón's sights and attractions like Amber World Museum, Museo Mundo del Ambar / Amber World Museum and Museo del Duarte offer insight into the local culture. Fuerte de Santa Bárbara and Iglesia de Santa Bárbara are also a couple of places to visit in the neighbourhood. Museo del Ron y la Caña, Casa del Cordón and Chinatown are just a few of the places to visit in and around San Antón. When you're sightseeing in Santo Domingo, Centro Cultural de las Telecomunicaciones and Plaza de España are also worth a stop.