Santa Cruz Travel Guide

Tourist Guide

A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.
A historic plaza with ornate Gothic architecture, palm trees, and people walking.
A narrow street lined with trees and buildings, with people sitting at outdoor cafes.
A sunny urban square with tram tracks, historic buildings, and pedestrians.
A historic building with ornate columns, a large archway, and a statue.

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
Once a Moorish fort, this architectural gem is now the oldest functioning palace in Europe.
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Activities

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

AU$59
per adult
88% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
Interior courtyard of a place with garden and reflecting pool in Granada

Seville Guided Tour with Fast-Track Entry to Alcázar, Cathedral & Giralda

AU$123
per adult
88% of travellers recommend
Seville Guided Tour with Fast-Track Entry to Alcázar, Cathedral & Giralda
Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla

Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla

AU$178
per adult
94% of travellers recommend
Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla
Landscape of Guadalquivir river area with several buildings in view.

Guadalquivir River Criuse Tour

AU$31
per adult
80% of travellers recommend
Guadalquivir River Criuse Tour
Alcázar of Seville Tour

Alcázar of Seville Guided Tour (Tickets Included & Preferred Line)

AU$63
per adult
Alcázar of Seville Guided Tour (Tickets Included & Preferred Line)
Picture 12 for Activity Seville: Bullring Guided Tour & Skip-the-Line Ticket

Seville: Bullring Guided Tour with a Skip-the-Line Ticket

AU$44
per adult
84% of travellers recommend
Seville: Bullring Guided Tour with a Skip-the-Line Ticket
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Our pick of the best Santa Cruz Hotel Deals

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
The price is AU$175 per night from 2 Dec to 3 Dec
AU$175
2 Dec - 3 Dec
includes taxes & fees
Stay at this spa hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
9.2/10 Wonderful! (1,027 reviews)
"great location and everythikng else"

Reviewed on 1 Nov 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
The price is AU$207 per night from 22 Nov to 23 Nov
AU$207
22 Nov - 23 Nov
includes taxes & fees
Stay at this boutique hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the breakfast and the bar in their reviews. ...
9.6/10 Exceptional! (1,301 reviews)
"Beautiful historic building in the heart of Barrio Santa Cruz. The music theme is well done throughout. Gorgeous decor with a modern touch. Room was spacious, clean, with all the modern appointments. For the location and modern charm you can’t beat this hotel."

Reviewed on 3 Nov 2026

Hotel Amadeus Sevilla
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
The price is AU$834 per night from 6 Dec to 7 Dec
AU$834
6 Dec - 7 Dec
includes taxes & fees
Stay at this luxury hotel in Seville. Enjoy 2 restaurants, breakfast (surcharge) and 24-hour room service. Our guests praise the helpful staff in their reviews. ...
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
The price is AU$190 per night from 29 Nov to 30 Nov
AU$190
29 Nov - 30 Nov
includes taxes & fees
Stay at this business-friendly hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their ...
Hotel Fernando III
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
The price is AU$190 per night from 29 Nov to 30 Nov
AU$190
29 Nov - 30 Nov
includes taxes & fees
Stay at this hotel in Seville. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...
Hotel Rey Alfonso X
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
The price is AU$122 per night from 2 Dec to 3 Dec
AU$122
2 Dec - 3 Dec
includes taxes & fees
Stay at this family-friendly hotel in Seville. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,110 reviews)
"Excelente ubicación"

Reviewed on 4 Nov 2026

Hotel Murillo
See all 411 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.
A bustling urban street lined with historic buildings and trees.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

A river with boats, a historic tower, and a cityscape with trees and buildings.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

A modern architectural structure with a unique, wave-like design.
Photo by Daniel Villafruela.
Open Photo by Daniel Villafruela.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

A large, illuminated bridge with circular arches over a calm river.

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

A modern stadium with a unique curved roof structure, surrounded by urban buildings and a prominent tower in the background.
Photo by Filippo Arena
Open Photo by Filippo Arena

San Bartolomé

Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

Santa Cruz Travel Guide

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