A forested area with a large rock formation and a narrow passageway.

Luxury Hotels & Resorts in Panama from AU$144

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Check availability on Panama Luxury Hotels

Tonight
21 Sept - 22 Sept
Tomorrow
22 Sept - 23 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Panama luxury hotels

1. DoubleTree by Hilton Jamestown

DoubleTree by Hilton Jamestown
Jamestown
AU$193
includes taxes & fees
21 Oct - 22 Oct
DoubleTree by Hilton Jamestown
View all properties

Top Panama Hotel Reviews

La Quinta Inn & Suites by Wyndham Jamestown

La Quinta Inn & Suites by Wyndham Jamestown

8/10 Good
"Room was clean. Could’ve had more parking. Breakfast was good. Would stay again."
Carol 1-night trip
Posted 15 hours ago
La Quinta Inn & Suites by Wyndham Jamestown
Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG

10/10 Excellent
"Great breakfast and clean room."
Amy 1-night trip
Posted 16 hours ago
Holiday Inn Express Hotel & Suites in North East (Erie) by IHG
Quality Inn & Suites Warren

Quality Inn & Suites Warren

8/10 Good
"We stayed one night, which was all we needed."
Kevin 1-night trip
Posted 20 hours ago
Quality Inn & Suites Warren

Frequently asked questions

Are you looking for a luxury hotel for your stay in Panama?
Use Expedia to arrange your flight to Jamestown, NY (JHW-Chautauqua County) airport or Erie, PA (ERI-Erie Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you'd like to make your stay special. If you want a posh hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Panama has to offer. Panama has some interesting things to see and do including Panama Rocks Scenic Park and Heron Farm & Event Center, so you might want to take in the local sights during your visit.
When can I expect good weather in Panama?
Planning for the weather is a good way to make your trip to Panama relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 19°C, while the coldest months are January and February, with an average of -2°C. The snowiest months in Panama are January, November, March and December, with each month seeing an average of 21 cm of snowfall.
What's there to see and do in Panama?
When you're in Panama, enjoy exploring the sights and attractions here including Chautauqua Lake, Long Point on Lake Chatauqua State Park and Chautauqua Institution. If you have some spare time during your trip, you might want to check out Panama Rocks Scenic Park and Heron Farm & Event Center.

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