
New Madrid County Holidays
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- Plan, book, travel with confidence
- Better togetherSave up to AU$703 when you book a flight and hotel together*
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Your New Madrid County Holiday
With a New Madrid County holiday package, you can forget about planning hassles and focus on experiencing all this wonderful destination has on offer. During your trip to New Madrid County, you'll want to tick off a few of its most famous cities. What can't you miss? Portageville. Stop dreaming and start packing, because your New Madrid County holiday is only a few clicks away with Expedia.
New Madrid County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
Population | 3,000 |
Our pick of the best New Madrid County Hotel Deals

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$169 per night from 8 Feb to 9 Feb
AU$169
8 Feb - 9 Feb
includes taxes & fees
8.8/10 Excellent! (456 reviews)
We were stranded in Matthews, MO and this hotel was very accommodating to our situation. The staff were professional and friendly! The manager even had a staff member provide us with a ride to the nearest car rental place. The hotel was clean with great amenities! We even received a call after our ...
Reviewed on 30 Dec 2025

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is AU$171 per night from 17 Jan to 18 Jan
AU$171
17 Jan - 18 Jan
includes taxes & fees
9.2/10 Wonderful! (47 reviews)
Staff promptly fixed a problem, room smelled very clean.
Reviewed on 3 Jan 2026

New Orleans Inn Portageville
600 US-61 Portageville MO
Fully refundableReserve now, pay when you stay
8/10 Very Good! (733 reviews)
They were very nice. The room was clean and the bed comfortable. The building is old and the room had some older carpet and drywall in need of repair
Reviewed on 1 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.











